<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:2aa6129c-9c23-4308-bd14-f2803835eae1,g:c61e69bf-763d-445f-854d-7245a7b23731-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.humacyte.com/role/CoverPage" xlink:type="simple" xlink:href="huma-20250930.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_46b2e48e-c85c-48d2-aa7a-d58ca8bbd382" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationTable_45bf31ba-1be8-40aa-850a-065d43472235" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentInformationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_46b2e48e-c85c-48d2-aa7a-d58ca8bbd382" xlink:to="loc_dei_DocumentInformationTable_45bf31ba-1be8-40aa-850a-065d43472235" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_6a9cdeff-3e0f-4b44-9b72-462c011ce800" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationTable_45bf31ba-1be8-40aa-850a-065d43472235" xlink:to="loc_us-gaap_StatementClassOfStockAxis_6a9cdeff-3e0f-4b44-9b72-462c011ce800" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_32563302-a618-4ea3-9583-2b19c3ed5a00" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_6a9cdeff-3e0f-4b44-9b72-462c011ce800" xlink:to="loc_us-gaap_ClassOfStockDomain_32563302-a618-4ea3-9583-2b19c3ed5a00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_1c1fbbee-3098-48eb-ab29-d6d8d242d227" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_32563302-a618-4ea3-9583-2b19c3ed5a00" xlink:to="loc_us-gaap_CommonStockMember_1c1fbbee-3098-48eb-ab29-d6d8d242d227" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RedeemableWarrantsEachWholeWarrantExercisableForOneShareOfCommonStockAtAnExercisePriceOf1150Member_da30e9df-3ce6-49dc-84af-8a9c9b9d26e0" xlink:href="huma-20250930.xsd#huma_RedeemableWarrantsEachWholeWarrantExercisableForOneShareOfCommonStockAtAnExercisePriceOf1150Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_32563302-a618-4ea3-9583-2b19c3ed5a00" xlink:to="loc_huma_RedeemableWarrantsEachWholeWarrantExercisableForOneShareOfCommonStockAtAnExercisePriceOf1150Member_da30e9df-3ce6-49dc-84af-8a9c9b9d26e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentInformationLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationTable_45bf31ba-1be8-40aa-850a-065d43472235" xlink:to="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_4cdc9063-2cf8-4899-a706-199700689b8a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentType_4cdc9063-2cf8-4899-a706-199700689b8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_b647bdcd-4a92-485d-9cae-9dbc63846573" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentQuarterlyReport_b647bdcd-4a92-485d-9cae-9dbc63846573" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_9da0ac8f-5e6e-4872-ba5c-2c65656b2175" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentPeriodEndDate_9da0ac8f-5e6e-4872-ba5c-2c65656b2175" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_1a049aff-020b-465f-bd5b-79be9c8274f5" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentTransitionReport_1a049aff-020b-465f-bd5b-79be9c8274f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_5225ef2f-2305-4474-a6b9-af7a85bc7d1a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityFileNumber_5225ef2f-2305-4474-a6b9-af7a85bc7d1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_cbaf8375-4dde-465a-8368-e12d9c5d6beb" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityRegistrantName_cbaf8375-4dde-465a-8368-e12d9c5d6beb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_883e683b-a3e5-4cb3-b641-440d555f4f52" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityIncorporationStateCountryCode_883e683b-a3e5-4cb3-b641-440d555f4f52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_9a269f23-e13b-455b-ac91-240a2532f06f" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityTaxIdentificationNumber_9a269f23-e13b-455b-ac91-240a2532f06f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_3aee6c93-6122-4839-aec1-f26a2436e650" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityAddressAddressLine1_3aee6c93-6122-4839-aec1-f26a2436e650" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_e1dfeff9-2da0-4d68-aef8-6d551a835c28" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityAddressCityOrTown_e1dfeff9-2da0-4d68-aef8-6d551a835c28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_06983ce3-b86c-48b6-8c51-dd24e7a62373" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityAddressStateOrProvince_06983ce3-b86c-48b6-8c51-dd24e7a62373" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_4bfb3112-d86b-4b7b-ad66-5fddfb62e8ba" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityAddressPostalZipCode_4bfb3112-d86b-4b7b-ad66-5fddfb62e8ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_aa431333-bb79-4029-a55a-56634c40f30e" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_CityAreaCode_aa431333-bb79-4029-a55a-56634c40f30e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_9b630b68-39fd-4c1f-9ed4-8d690cdc9b69" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_LocalPhoneNumber_9b630b68-39fd-4c1f-9ed4-8d690cdc9b69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_e6f6459a-2eae-4a4a-b96e-df356c0d79a8" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_Security12bTitle_e6f6459a-2eae-4a4a-b96e-df356c0d79a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_7f87f14f-d7d0-452e-9676-f0de0cebdbf7" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_TradingSymbol_7f87f14f-d7d0-452e-9676-f0de0cebdbf7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_30ed001a-1859-4767-a76c-6c09e98ce256" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_SecurityExchangeName_30ed001a-1859-4767-a76c-6c09e98ce256" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_f56baf31-fdf4-40b5-80e9-5f47c609da8a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityCurrentReportingStatus_f56baf31-fdf4-40b5-80e9-5f47c609da8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_36770abf-3cef-4a2e-916e-37a7a8e9fb3c" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityInteractiveDataCurrent_36770abf-3cef-4a2e-916e-37a7a8e9fb3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_3efef9bc-ff9f-4efa-b53a-eb53e63bcfde" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityFilerCategory_3efef9bc-ff9f-4efa-b53a-eb53e63bcfde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_98210ae6-4dd9-4791-ad60-5163b4fa00fa" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntitySmallBusiness_98210ae6-4dd9-4791-ad60-5163b4fa00fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_3adafd1b-77ed-46d6-8fdf-b434c9a0ca46" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityEmergingGrowthCompany_3adafd1b-77ed-46d6-8fdf-b434c9a0ca46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityExTransitionPeriod_e8c898cb-c5af-43b2-a2eb-fa0805105a7e" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityExTransitionPeriod"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityExTransitionPeriod_e8c898cb-c5af-43b2-a2eb-fa0805105a7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_b0493878-9d47-4f55-992b-86aff0341898" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityShellCompany_b0493878-9d47-4f55-992b-86aff0341898" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_fd21304a-85c8-4af6-910e-ccc176504106" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_fd21304a-85c8-4af6-910e-ccc176504106" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_e4e129a1-ccef-4aee-aab3-f70272185ec9" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_EntityCentralIndexKey_e4e129a1-ccef-4aee-aab3-f70272185ec9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_e87e9e51-edc8-4e1b-a2e7-1066ad10ecaa" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_CurrentFiscalYearEndDate_e87e9e51-edc8-4e1b-a2e7-1066ad10ecaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_d4d5a0e8-b50f-45a4-bb6a-b2066f65e004" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentFiscalYearFocus_d4d5a0e8-b50f-45a4-bb6a-b2066f65e004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_9f91a440-5f4b-4177-9dfb-9f15f2bf1def" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_DocumentFiscalPeriodFocus_9f91a440-5f4b-4177-9dfb-9f15f2bf1def" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_1c818386-4b85-494e-b6fd-9ea373d5991b" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_7e2c4ded-33ee-43c0-a70a-6593fabc24dd" xlink:to="loc_dei_AmendmentFlag_1c818386-4b85-494e-b6fd-9ea373d5991b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="huma-20250930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_61108a22-38b1-426a-ad37-59c53e4a7ae5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_61108a22-38b1-426a-ad37-59c53e4a7ae5" xlink:to="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_cfefd29c-debc-4350-832e-649c1aa3cce7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_cfefd29c-debc-4350-832e-649c1aa3cce7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_9a919d06-0f0c-403e-96bd-480427f1d7c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:to="loc_us-gaap_InventoryNet_9a919d06-0f0c-403e-96bd-480427f1d7c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_064797c2-5165-49af-9ee5-5f08f96deeed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_064797c2-5165-49af-9ee5-5f08f96deeed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_23f961a3-7dc3-43b0-81e8-b8c8779aa44b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_23f961a3-7dc3-43b0-81e8-b8c8779aa44b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_9f91871a-88ac-4b60-b046-dcd985df55f7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1b67f2f5-e153-4572-8e0e-7c20a39d3623" xlink:to="loc_us-gaap_AssetsCurrent_9f91871a-88ac-4b60-b046-dcd985df55f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashNoncurrent_f1145d1a-7bf7-408d-b722-989bbfd59de8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_RestrictedCashNoncurrent_f1145d1a-7bf7-408d-b722-989bbfd59de8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_09a4815c-7934-4557-9caf-2c9936c74ca1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_09a4815c-7934-4557-9caf-2c9936c74ca1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_6e3545fa-c649-40d4-9a62-43fc8cda3327" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseRightOfUseAsset"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_6e3545fa-c649-40d4-9a62-43fc8cda3327" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_51694303-e0bf-4b24-b150-acf9c50fa1fc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_51694303-e0bf-4b24-b150-acf9c50fa1fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_7de5235c-d992-4ec5-bd9f-66dbd1e7d1cf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_7f5d70b3-1855-486e-a2f4-c02a496c4615" xlink:to="loc_us-gaap_Assets_7de5235c-d992-4ec5-bd9f-66dbd1e7d1cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_61108a22-38b1-426a-ad37-59c53e4a7ae5" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_2d985374-c47d-43e7-a32f-2efb6f50838e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_AccountsPayableCurrent_2d985374-c47d-43e7-a32f-2efb6f50838e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_c23b7b8b-fcc4-487e-aec7-ea0fb9983725" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_c23b7b8b-fcc4-487e-aec7-ea0fb9983725" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_f98ab0e0-8865-4822-bf98-eeba2495b688" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_f98ab0e0-8865-4822-bf98-eeba2495b688" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtCurrent_d6798a08-f5f2-482c-9c87-8e5997a8cb0d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_UnsecuredDebtCurrent_d6798a08-f5f2-482c-9c87-8e5997a8cb0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesCurrent_383ee536-218b-404f-8a12-ca41b2753fed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_OtherLiabilitiesCurrent_383ee536-218b-404f-8a12-ca41b2753fed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_f84df110-774c-4590-9af6-7e97ddcb0b5b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_45d8cde9-43ab-44b6-9a7c-d64e282d245f" xlink:to="loc_us-gaap_LiabilitiesCurrent_f84df110-774c-4590-9af6-7e97ddcb0b5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredLongTermDebt_13aaeb61-7bc1-467d-a4e7-5952d455b945" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredLongTermDebt"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_UnsecuredLongTermDebt_13aaeb61-7bc1-467d-a4e7-5952d455b945" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_e3c31b63-ad37-4552-8a63-5b72f9e9576c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_e3c31b63-ad37-4552-8a63-5b72f9e9576c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_3e597e1e-fe1f-4974-9407-a4fb3106166a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_3e597e1e-fe1f-4974-9407-a4fb3106166a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_b5e8563a-2cb9-4741-8e5a-b0f9598f777b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_b5e8563a-2cb9-4741-8e5a-b0f9598f777b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilitiesNoncurrent_f8d7c262-cd02-4e8e-95f7-c0c2ae7d4c93" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeLiabilitiesNoncurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_DerivativeLiabilitiesNoncurrent_f8d7c262-cd02-4e8e-95f7-c0c2ae7d4c93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_f76d04a3-515d-4c60-abd8-e03a96aeca45" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_f76d04a3-515d-4c60-abd8-e03a96aeca45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_50818e7e-1c42-4e1a-bfd2-1f4ad0b76555" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_Liabilities_50818e7e-1c42-4e1a-bfd2-1f4ad0b76555" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_9b62b065-74ab-4b34-adbf-7f54c99fbdf5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_CommitmentsAndContingencies_9b62b065-74ab-4b34-adbf-7f54c99fbdf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_4c99b525-802b-49ae-bebf-f3d345f49c19" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:to="loc_us-gaap_PreferredStockValue_4c99b525-802b-49ae-bebf-f3d345f49c19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_60bf5542-4f73-4e0b-b0b3-de27abadbd2f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:to="loc_us-gaap_CommonStockValue_60bf5542-4f73-4e0b-b0b3-de27abadbd2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_d5f42fba-b543-47dc-899f-207e9848d69e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:to="loc_us-gaap_AdditionalPaidInCapital_d5f42fba-b543-47dc-899f-207e9848d69e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_f2b1aca6-b2bc-4b47-a2de-cf00d8f52c10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_f2b1aca6-b2bc-4b47-a2de-cf00d8f52c10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_870aa134-14a9-46ae-985e-28f0d1413306" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_1094ab61-b760-474b-8f51-698b1f90ff2a" xlink:to="loc_us-gaap_StockholdersEquity_870aa134-14a9-46ae-985e-28f0d1413306" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_359ffeb4-79ad-4697-a889-237e3ccf252b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_bc49bf8d-edf9-4f59-a326-e6cb0b3b945b" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_359ffeb4-79ad-4697-a889-237e3ccf252b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="huma-20250930.xsd#CondensedConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2ea92e01-eaa8-4db0-adaf-7263452864a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2ea92e01-eaa8-4db0-adaf-7263452864a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_baea915e-3690-412a-975c-6da044582ac7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_baea915e-3690-412a-975c-6da044582ac7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_b377c75d-a11f-4d93-954e-587e3e288570" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_PreferredStockSharesIssued_b377c75d-a11f-4d93-954e-587e3e288570" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_0c20e49d-9a98-416a-a7d1-43842a444a50" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_0c20e49d-9a98-416a-a7d1-43842a444a50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_b5d05330-41b3-4467-ba9c-755cf85384d8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_b5d05330-41b3-4467-ba9c-755cf85384d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_bc805858-b4ab-4976-8622-6a964141f809" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_bc805858-b4ab-4976-8622-6a964141f809" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_f2ff6563-fbda-4e66-b634-dfaebad8f570" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_CommonStockSharesIssued_f2ff6563-fbda-4e66-b634-dfaebad8f570" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_d1393ee8-7729-456c-a5fd-f80400cdb5bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_c4799fb8-8485-4a02-b29d-29789544efd0" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_d1393ee8-7729-456c-a5fd-f80400cdb5bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="simple" xlink:href="huma-20250930.xsd#CondensedConsolidatedStatementsofOperationsandComprehensiveLoss"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_87d97d57-da4f-45c2-9e70-6350b1717c78" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_8574fdc0-89d5-401a-a977-2e7fb80aba9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_87d97d57-da4f-45c2-9e70-6350b1717c78" xlink:to="loc_us-gaap_StatementTable_8574fdc0-89d5-401a-a977-2e7fb80aba9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_b79d34fe-f662-4c24-96de-79e4c06de30c" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_8574fdc0-89d5-401a-a977-2e7fb80aba9c" xlink:to="loc_srt_ProductOrServiceAxis_b79d34fe-f662-4c24-96de-79e4c06de30c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_c33d6d59-79ac-45b9-a33a-1b126da961a6" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_b79d34fe-f662-4c24-96de-79e4c06de30c" xlink:to="loc_srt_ProductsAndServicesDomain_c33d6d59-79ac-45b9-a33a-1b126da961a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_7dcbbe86-f415-460d-a57d-d3d2569f432c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_c33d6d59-79ac-45b9-a33a-1b126da961a6" xlink:to="loc_us-gaap_ProductMember_7dcbbe86-f415-460d-a57d-d3d2569f432c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_d11cea39-cdec-47fb-b0d1-cf2e6458b18b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_c33d6d59-79ac-45b9-a33a-1b126da961a6" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_d11cea39-cdec-47fb-b0d1-cf2e6458b18b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_8574fdc0-89d5-401a-a977-2e7fb80aba9c" xlink:to="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_5d1c836d-a36a-4e55-ba90-47634d206c4d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenuesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_RevenuesAbstract_5d1c836d-a36a-4e55-ba90-47634d206c4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_b34100d1-66b4-48d1-804e-577d77f0eb8e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_5d1c836d-a36a-4e55-ba90-47634d206c4d" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_b34100d1-66b4-48d1-804e-577d77f0eb8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_a0a85070-2fe4-4718-ae24-633663f6b8bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_a0a85070-2fe4-4718-ae24-633663f6b8bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_ce3da8aa-fc3d-4c57-8077-69877c9d49c0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_ce3da8aa-fc3d-4c57-8077-69877c9d49c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_3d5e55c3-7567-4262-a999-2f97b8640638" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_3d5e55c3-7567-4262-a999-2f97b8640638" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_1aa163f9-de7a-4481-beb4-17db3ebda2c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostsAndExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8570a80a-ce03-4c3e-b61b-d84092fea1e9" xlink:to="loc_us-gaap_CostsAndExpenses_1aa163f9-de7a-4481-beb4-17db3ebda2c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_481ff1c8-deca-4d56-be48-a2b5859fca40" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_OperatingIncomeLoss_481ff1c8-deca-4d56-be48-a2b5859fca40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpenseAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_5f7b05a6-ef48-4a75-af64-ae3ca76219cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:to="loc_us-gaap_InvestmentIncomeInterest_5f7b05a6-ef48-4a75-af64-ae3ca76219cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_bdcde6b7-fab1-428d-8eff-7d9a5853b2c6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_bdcde6b7-fab1-428d-8eff-7d9a5853b2c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnDerivatives_cc909934-45a2-4df2-8900-5d9a9821237a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnrealizedGainLossOnDerivatives"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:to="loc_us-gaap_UnrealizedGainLossOnDerivatives_cc909934-45a2-4df2-8900-5d9a9821237a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_b57fa831-94d7-4f43-bcc0-41019a9922f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:to="loc_us-gaap_InterestExpenseNonoperating_b57fa831-94d7-4f43-bcc0-41019a9922f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_4a1d9175-7d56-4cb1-b744-46ec10f7c6e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_b6e72419-6667-4871-85de-2a9fc6e072c2" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_4a1d9175-7d56-4cb1-b744-46ec10f7c6e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_9901f451-b8a1-46fc-ac72-f680a7d19b2f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_NetIncomeLoss_9901f451-b8a1-46fc-ac72-f680a7d19b2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_20e9abb3-6368-469a-8908-5f16b1493974" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_20e9abb3-6368-469a-8908-5f16b1493974" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_bcb9c94f-0c92-47f4-8838-a41ec937d6a4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_EarningsPerShareBasic_bcb9c94f-0c92-47f4-8838-a41ec937d6a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_d473973d-a52f-4322-885b-d84e87527c95" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_EarningsPerShareDiluted_d473973d-a52f-4322-885b-d84e87527c95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_95e5a491-79de-4162-897c-34750179ba42" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_95e5a491-79de-4162-897c-34750179ba42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_86074738-71d5-4e15-9ce4-74f6dde4757c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_83a773b9-ae0a-4d05-9dbe-582cd99692ca" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_86074738-71d5-4e15-9ce4-74f6dde4757c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CondensedConsolidatedStatementsofChangesinStockholdersEquityDeficit" xlink:type="simple" xlink:href="huma-20250930.xsd#CondensedConsolidatedStatementsofChangesinStockholdersEquityDeficit"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CondensedConsolidatedStatementsofChangesinStockholdersEquityDeficit" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_82eb4419-9fc4-4412-aa18-012971945b7a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_82eb4419-9fc4-4412-aa18-012971945b7a" xlink:to="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_f657ed4e-763e-4ddc-842d-f4acc8f21803" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_f657ed4e-763e-4ddc-842d-f4acc8f21803" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_1ef45b7e-7570-40d4-9e5d-7a45c5be70c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_f657ed4e-763e-4ddc-842d-f4acc8f21803" xlink:to="loc_us-gaap_EquityComponentDomain_1ef45b7e-7570-40d4-9e5d-7a45c5be70c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_be6f96e2-55eb-44cd-a722-510cb0cc5119" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_1ef45b7e-7570-40d4-9e5d-7a45c5be70c1" xlink:to="loc_us-gaap_CommonStockMember_be6f96e2-55eb-44cd-a722-510cb0cc5119" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_9a25d15a-4434-40d5-893b-5d62b53b9551" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_1ef45b7e-7570-40d4-9e5d-7a45c5be70c1" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_9a25d15a-4434-40d5-893b-5d62b53b9551" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_634cf861-89ec-4cf8-8ad5-ad51a37eaeca" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_1ef45b7e-7570-40d4-9e5d-7a45c5be70c1" xlink:to="loc_us-gaap_RetainedEarningsMember_634cf861-89ec-4cf8-8ad5-ad51a37eaeca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_693696ed-f6cc-411c-8573-b9a7116665a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_693696ed-f6cc-411c-8573-b9a7116665a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a78e037b-b457-436a-aa75-763d3b609bf9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_693696ed-f6cc-411c-8573-b9a7116665a1" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a78e037b-b457-436a-aa75-763d3b609bf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PublicStockOfferingMember_66db4464-5013-486b-b300-4afba67e90f1" xlink:href="huma-20250930.xsd#huma_PublicStockOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a78e037b-b457-436a-aa75-763d3b609bf9" xlink:to="loc_huma_PublicStockOfferingMember_66db4464-5013-486b-b300-4afba67e90f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ATMFacilityMember_38bded1a-046c-47c5-affa-9cdfcd232750" xlink:href="huma-20250930.xsd#huma_ATMFacilityMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a78e037b-b457-436a-aa75-763d3b609bf9" xlink:to="loc_huma_ATMFacilityMember_38bded1a-046c-47c5-affa-9cdfcd232750" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_12c04a6e-1d47-423e-88fb-d822127da640" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a78e037b-b457-436a-aa75-763d3b609bf9" xlink:to="loc_huma_EquityLineFinancingMember_12c04a6e-1d47-423e-88fb-d822127da640" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_6c4a419a-00a6-41d0-8463-b56a33b41588" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:to="loc_us-gaap_StatementClassOfStockAxis_6c4a419a-00a6-41d0-8463-b56a33b41588" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_5124141c-6302-4323-88b8-6bc616b4e0b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_6c4a419a-00a6-41d0-8463-b56a33b41588" xlink:to="loc_us-gaap_ClassOfStockDomain_5124141c-6302-4323-88b8-6bc616b4e0b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommitmentSharesMember_7f8f68e0-f7e2-445f-b8cb-422748347037" xlink:href="huma-20250930.xsd#huma_CommitmentSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_5124141c-6302-4323-88b8-6bc616b4e0b2" xlink:to="loc_huma_CommitmentSharesMember_7f8f68e0-f7e2-445f-b8cb-422748347037" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_fb21f99f-a1b5-4512-8396-3ae5f749b513" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_40f1bac7-1ffe-445a-82d9-9576dc60b502" xlink:to="loc_us-gaap_StatementLineItems_fb21f99f-a1b5-4512-8396-3ae5f749b513" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_fb21f99f-a1b5-4512-8396-3ae5f749b513" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_b54be630-82c7-4bb5-bc5f-a62764cf5900" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_b54be630-82c7-4bb5-bc5f-a62764cf5900" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_9181ee29-f4d5-442b-9a11-6aea83e8368e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockholdersEquity_9181ee29-f4d5-442b-9a11-6aea83e8368e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_b7c02d30-c550-4370-8fdb-a739d408a91f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_b7c02d30-c550-4370-8fdb-a739d408a91f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_437d098e-3325-497a-9878-883252f08b8e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_437d098e-3325-497a-9878-883252f08b8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_48c59cb6-dacb-49cf-acd3-6989791fafe8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_48c59cb6-dacb-49cf-acd3-6989791fafe8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_d71aa978-262b-43cd-97bc-c1dd5f1861d2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_d71aa978-262b-43cd-97bc-c1dd5f1861d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_9aedf25a-f1a6-4a1d-b69c-0f1d53cfb6b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_9aedf25a-f1a6-4a1d-b69c-0f1d53cfb6b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_8d05dbef-b699-4a28-92a2-b206d187412b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_NetIncomeLoss_8d05dbef-b699-4a28-92a2-b206d187412b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_9f0bb9d5-7ac0-409f-8fac-82ce181cd759" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_9f0bb9d5-7ac0-409f-8fac-82ce181cd759" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_9e1b4ed4-043e-4171-9997-59fdcaae66e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_665c0aa8-3eb6-4e44-aa20-87d0e615cafd" xlink:to="loc_us-gaap_StockholdersEquity_9e1b4ed4-043e-4171-9997-59fdcaae66e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="huma-20250930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_b19b0dae-ff41-44c6-9e18-2dfaafa434dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_eed4f753-95df-4057-893a-8a5078e79bc8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_b19b0dae-ff41-44c6-9e18-2dfaafa434dd" xlink:to="loc_us-gaap_StatementTable_eed4f753-95df-4057-893a-8a5078e79bc8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_1fd3a4fa-0c71-43a9-9fc3-1cf3902a469b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_eed4f753-95df-4057-893a-8a5078e79bc8" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_1fd3a4fa-0c71-43a9-9fc3-1cf3902a469b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_b6f69aac-9d78-43b5-9447-e28de1addb96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_1fd3a4fa-0c71-43a9-9fc3-1cf3902a469b" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_b6f69aac-9d78-43b5-9447-e28de1addb96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PublicStockOfferingMember_5555ca8f-df7f-4c1f-80c2-54d995b43a95" xlink:href="huma-20250930.xsd#huma_PublicStockOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_b6f69aac-9d78-43b5-9447-e28de1addb96" xlink:to="loc_huma_PublicStockOfferingMember_5555ca8f-df7f-4c1f-80c2-54d995b43a95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ATMFacilityMember_0f2a056c-a141-449f-87a6-78e72d32dcd4" xlink:href="huma-20250930.xsd#huma_ATMFacilityMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_b6f69aac-9d78-43b5-9447-e28de1addb96" xlink:to="loc_huma_ATMFacilityMember_0f2a056c-a141-449f-87a6-78e72d32dcd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_fbf7d92d-29a6-4fb1-8653-e8f9fb7dacff" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_b6f69aac-9d78-43b5-9447-e28de1addb96" xlink:to="loc_huma_EquityLineFinancingMember_fbf7d92d-29a6-4fb1-8653-e8f9fb7dacff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_eed4f753-95df-4057-893a-8a5078e79bc8" xlink:to="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_d59c80e3-63ee-421b-8827-f8ea4dd9dcb0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_d59c80e3-63ee-421b-8827-f8ea4dd9dcb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_79f04fd6-6de6-415e-9f87-d7b5f55d04fd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_d59c80e3-63ee-421b-8827-f8ea4dd9dcb0" xlink:to="loc_us-gaap_NetIncomeLoss_79f04fd6-6de6-415e-9f87-d7b5f55d04fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_d59c80e3-63ee-421b-8827-f8ea4dd9dcb0" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_cf25b669-998c-422c-b931-ee3695aeecde" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_Depreciation_cf25b669-998c-422c-b931-ee3695aeecde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_554a2f15-2e30-4b54-8684-ef8a2426e34c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_ShareBasedCompensation_554a2f15-2e30-4b54-8684-ef8a2426e34c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_4f2ec4d7-dba5-4886-b95f-a9a907967954" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_4f2ec4d7-dba5-4886-b95f-a9a907967954" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseInterestBearingLiability_49fbaae0-4766-4084-9315-9f86e60438de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseInterestBearingLiability"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_InterestExpenseInterestBearingLiability_49fbaae0-4766-4084-9315-9f86e60438de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnDerivatives_e4c9cd33-075c-4711-9ece-83169063842a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnrealizedGainLossOnDerivatives"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_UnrealizedGainLossOnDerivatives_e4c9cd33-075c-4711-9ece-83169063842a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_c8d958b2-48ac-4348-a8dd-5159e968239b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_c8d958b2-48ac-4348-a8dd-5159e968239b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_b1be55d1-ccad-410f-81bd-f493538894d7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_b1be55d1-ccad-410f-81bd-f493538894d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_bb2da68c-9614-4813-bb85-8c0e1fe96fbf" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_e894faf1-f981-4317-bd2d-dc4ff4d33ba8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_e894faf1-f981-4317-bd2d-dc4ff4d33ba8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_5097f42b-93b0-44df-aaf8-f44687de2a3f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_5097f42b-93b0-44df-aaf8-f44687de2a3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_3cf6e19a-d281-4537-89ea-3ece98f461e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_3cf6e19a-d281-4537-89ea-3ece98f461e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_8ae2a292-b5cf-4210-b12d-5bb81ec5a144" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_8ae2a292-b5cf-4210-b12d-5bb81ec5a144" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_6bea3adf-0786-4e1f-8d4a-35a3ddc2a161" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_6bea3adf-0786-4e1f-8d4a-35a3ddc2a161" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_8258c565-6326-429f-87a8-293ddcf92ad9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOperatingLeaseLiability"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_673c0302-7b70-4143-8002-93efa9752c70" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_8258c565-6326-429f-87a8-293ddcf92ad9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_6a898787-2bd8-4061-8050-902fa187ee52" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_d59c80e3-63ee-421b-8827-f8ea4dd9dcb0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_6a898787-2bd8-4061-8050-902fa187ee52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_f4faeaf8-0f98-422d-9d70-3a3701ddcb0c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_f4faeaf8-0f98-422d-9d70-3a3701ddcb0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_2fc3fc83-ed08-477f-8b1c-8bd2d0037fa5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_f4faeaf8-0f98-422d-9d70-3a3701ddcb0c" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_2fc3fc83-ed08-477f-8b1c-8bd2d0037fa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1dc1fe03-9d5b-4016-a2e4-c3f2a1768b34" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_f4faeaf8-0f98-422d-9d70-3a3701ddcb0c" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1dc1fe03-9d5b-4016-a2e4-c3f2a1768b34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_a69253a9-7a34-490e-b0d0-2529794d9815" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_a69253a9-7a34-490e-b0d0-2529794d9815" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_df4fd951-3733-4f4a-a484-b11f28a9644a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_df4fd951-3733-4f4a-a484-b11f28a9644a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_af79b3a8-8cc6-4782-aaa0-47572c43a262" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_af79b3a8-8cc6-4782-aaa0-47572c43a262" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfOtherLongTermDebt_6bd2e13c-84ef-4429-bc1a-c0e0d16ee5bc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfOtherLongTermDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfOtherLongTermDebt_6bd2e13c-84ef-4429-bc1a-c0e0d16ee5bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_b1c52f61-d35b-4675-820e-732d1d6b7488" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_b1c52f61-d35b-4675-820e-732d1d6b7488" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_InterestExpenseDebtRevenueInterest_bc6acdbb-f8e8-4205-b0b9-4524e605cafa" xlink:href="huma-20250930.xsd#huma_InterestExpenseDebtRevenueInterest"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_huma_InterestExpenseDebtRevenueInterest_bc6acdbb-f8e8-4205-b0b9-4524e605cafa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_529432b9-c399-486f-862b-aa3544ccde1c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_529432b9-c399-486f-862b-aa3544ccde1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_fe776e2b-7fa4-49a0-842c-0bc537cbe141" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfUnsecuredDebt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_fe776e2b-7fa4-49a0-842c-0bc537cbe141" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PaymentsOfTransactionCosts_424e39e2-1d23-47fd-a5ff-5a595ef31c08" xlink:href="huma-20250930.xsd#huma_PaymentsOfTransactionCosts"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_huma_PaymentsOfTransactionCosts_424e39e2-1d23-47fd-a5ff-5a595ef31c08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_788416d5-85c2-4183-8d93-2f20a0629eba" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_b23ca4b8-da37-4e6a-816b-c7c597542d20" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_788416d5-85c2-4183-8d93-2f20a0629eba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_71b4e20e-7b17-4b9c-b3cc-1010e136b260" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_71b4e20e-7b17-4b9c-b3cc-1010e136b260" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_98e81cc8-49f7-415b-9b19-9078de722bdb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_98e81cc8-49f7-415b-9b19-9078de722bdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_26e1c4a8-ff3c-46bf-9fbe-a84626c011ab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_26e1c4a8-ff3c-46bf-9fbe-a84626c011ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_c2d46a4a-da24-4411-9530-d8a622e0cc58" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_d2f373fb-3a95-4db0-94b4-6de9e0683f71" xlink:to="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_c2d46a4a-da24-4411-9530-d8a622e0cc58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalLeaseObligationsIncurred_96b1267d-e818-4430-9fa7-ed945b57458e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CapitalLeaseObligationsIncurred"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_c2d46a4a-da24-4411-9530-d8a622e0cc58" xlink:to="loc_us-gaap_CapitalLeaseObligationsIncurred_96b1267d-e818-4430-9fa7-ed945b57458e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_NoncashContingentDerivativeLiability_ff36a14d-23ce-4221-9fec-54857742aa2d" xlink:href="huma-20250930.xsd#huma_NoncashContingentDerivativeLiability"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_c2d46a4a-da24-4411-9530-d8a622e0cc58" xlink:to="loc_huma_NoncashContingentDerivativeLiability_ff36a14d-23ce-4221-9fec-54857742aa2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssued1_62f8f473-87e8-41b0-a8f5-1b3fedcfbf3c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssued1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_c2d46a4a-da24-4411-9530-d8a622e0cc58" xlink:to="loc_us-gaap_StockIssued1_62f8f473-87e8-41b0-a8f5-1b3fedcfbf3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/OrganizationandDescriptionofBusiness" xlink:type="simple" xlink:href="huma-20250930.xsd#OrganizationandDescriptionofBusiness"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/OrganizationandDescriptionofBusiness" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3220a540-3d76-4624-98e9-a3f2c7f0ce9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_3cd2c6d3-d0db-4e0b-9cd0-273791f96bfc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3220a540-3d76-4624-98e9-a3f2c7f0ce9c" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_3cd2c6d3-d0db-4e0b-9cd0-273791f96bfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_c4927480-d8db-4e73-b5e0-29c34286bc32" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_ec1476f1-08ce-436a-9580-eb1909514624" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_c4927480-d8db-4e73-b5e0-29c34286bc32" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_ec1476f1-08ce-436a-9580-eb1909514624" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/FairValueMeasurements" xlink:type="simple" xlink:href="huma-20250930.xsd#FairValueMeasurements"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_e72570ad-469b-40aa-b800-b759ed149db9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_be7ae668-62e0-4504-985b-224bde01fa88" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_e72570ad-469b-40aa-b800-b759ed149db9" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_be7ae668-62e0-4504-985b-224bde01fa88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/Inventory" xlink:type="simple" xlink:href="huma-20250930.xsd#Inventory"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/Inventory" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_84310bff-9a75-4f39-bed7-c189ec642189" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_39db0468-8c14-41ec-aa7d-13dd4f19d8d3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_84310bff-9a75-4f39-bed7-c189ec642189" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_39db0468-8c14-41ec-aa7d-13dd4f19d8d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/PropertyandEquipmentNet" xlink:type="simple" xlink:href="huma-20250930.xsd#PropertyandEquipmentNet"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/PropertyandEquipmentNet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_7e5fcffc-c72f-498b-bf8d-b3d579a37ff0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_10fe166d-c2e9-4963-b635-9724f886c3e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_7e5fcffc-c72f-498b-bf8d-b3d579a37ff0" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_10fe166d-c2e9-4963-b635-9724f886c3e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/AccruedExpenses" xlink:type="simple" xlink:href="huma-20250930.xsd#AccruedExpenses"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/AccruedExpenses" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_1baeb796-e3da-472d-b8d2-93ba8ddce1c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_AccruedLiabilitiesDisclosureTextBlock_dea3797e-d5e0-4e0c-a84f-0751ee488357" xlink:href="huma-20250930.xsd#huma_AccruedLiabilitiesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_1baeb796-e3da-472d-b8d2-93ba8ddce1c8" xlink:to="loc_huma_AccruedLiabilitiesDisclosureTextBlock_dea3797e-d5e0-4e0c-a84f-0751ee488357" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RevenueInterestPurchaseAgreement" xlink:type="simple" xlink:href="huma-20250930.xsd#RevenueInterestPurchaseAgreement"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RevenueInterestPurchaseAgreement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_2c61be35-8d0d-4486-a572-b4020dd551b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_8b2bd6d5-0223-4fa3-bf8a-8f927bf2ecd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_2c61be35-8d0d-4486-a572-b4020dd551b2" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_8b2bd6d5-0223-4fa3-bf8a-8f927bf2ecd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/Leases" xlink:type="simple" xlink:href="huma-20250930.xsd#Leases"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/Leases" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_c0072cdf-7261-48a6-a386-7460bc734dce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_21bc6825-5f6d-4277-82fc-65deacb6b6fa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_c0072cdf-7261-48a6-a386-7460bc734dce" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_21bc6825-5f6d-4277-82fc-65deacb6b6fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeFinanceLeasesTextBlock_392be713-7782-4609-82e9-b07683adbbc5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeFinanceLeasesTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_c0072cdf-7261-48a6-a386-7460bc734dce" xlink:to="loc_us-gaap_LesseeFinanceLeasesTextBlock_392be713-7782-4609-82e9-b07683adbbc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrants" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrants"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrants" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_95c4c93e-8928-4e93-9a0b-2fef39a80629" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_4d21b329-0c67-47bb-b283-fca2301b68a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_95c4c93e-8928-4e93-9a0b-2fef39a80629" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_4d21b329-0c67-47bb-b283-fca2301b68a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensation" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensation"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_b7f39fe9-b3fc-4984-bc58-337dbc45ab9f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_deb751f8-4597-4b86-9966-8192e5768141" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_b7f39fe9-b3fc-4984-bc58-337dbc45ab9f" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_deb751f8-4597-4b86-9966-8192e5768141" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/IncomeTaxes" xlink:type="simple" xlink:href="huma-20250930.xsd#IncomeTaxes"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_72c96116-9d60-4244-b6c6-5c54dfb6182f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_d4e636e9-dd6b-4c63-9011-d5fb699afe36" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_72c96116-9d60-4244-b6c6-5c54dfb6182f" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_d4e636e9-dd6b-4c63-9011-d5fb699afe36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="huma-20250930.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_d75feb2e-93f1-4148-9571-2ec4e6e65505" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_49be72f6-2a70-439d-b450-eae99d282d2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_d75feb2e-93f1-4148-9571-2ec4e6e65505" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_49be72f6-2a70-439d-b450-eae99d282d2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RelatedPartyTransactions" xlink:type="simple" xlink:href="huma-20250930.xsd#RelatedPartyTransactions"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RelatedPartyTransactions" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_3b1fbbee-5e3b-4e9d-9b13-ee8348f469dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_c1a260e4-ae5a-49b4-a09e-6c7396261d01" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_3b1fbbee-5e3b-4e9d-9b13-ee8348f469dd" xlink:to="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_c1a260e4-ae5a-49b4-a09e-6c7396261d01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SubsequentEvents" xlink:type="simple" xlink:href="huma-20250930.xsd#SubsequentEvents"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_e7aa8137-82cc-42ac-a127-841b7e5c9049" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_33cb2707-19f9-46f3-9c5b-60f6b69d5a7b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_e7aa8137-82cc-42ac-a127-841b7e5c9049" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_33cb2707-19f9-46f3-9c5b-60f6b69d5a7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_4b75ab0b-af3c-4cf4-b221-aca6fc69c5e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_4b75ab0b-af3c-4cf4-b221-aca6fc69c5e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_b45f3e57-6600-41c1-81be-90bd5881d73c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConsolidationPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_b45f3e57-6600-41c1-81be-90bd5881d73c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_d73486c3-d2fb-4665-b8a6-db7807ef0fc2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_UseOfEstimates_d73486c3-d2fb-4665-b8a6-db7807ef0fc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_913a983b-5169-48df-9e38-63114424e9b6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PriorPeriodReclassificationAdjustmentDescription"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_913a983b-5169-48df-9e38-63114424e9b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_b40194b6-039e-43ae-9ff4-f2cb1b6d6d09" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_b40194b6-039e-43ae-9ff4-f2cb1b6d6d09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryPolicyTextBlock_fe579542-6812-48b0-ac25-b15f51a08d46" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryPolicyTextBlock"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_InventoryPolicyTextBlock_fe579542-6812-48b0-ac25-b15f51a08d46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_b7011666-7deb-4e88-98ba-53235866e8f4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_b7011666-7deb-4e88-98ba-53235866e8f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_d89ce693-4d76-40ee-b0f1-4afa1ec3f399" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskCreditRisk"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_d89ce693-4d76-40ee-b0f1-4afa1ec3f399" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_e863f210-9f00-4c96-a4dc-631bca1b59a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_e863f210-9f00-4c96-a4dc-631bca1b59a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_c714cb40-5389-47ee-9acf-36ef82b34edd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_c714cb40-5389-47ee-9acf-36ef82b34edd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_b62f45b1-bdc5-478e-b695-849d5fe3dae1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_b62f45b1-bdc5-478e-b695-849d5fe3dae1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_fc1cdf13-bc9a-4aa0-960f-901595b27728" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_fc1cdf13-bc9a-4aa0-960f-901595b27728" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesPolicyTextBlock_a245a9a9-2d11-4b7c-8d26-b8dc83d92c2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativesPolicyTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_DerivativesPolicyTextBlock_a245a9a9-2d11-4b7c-8d26-b8dc83d92c2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesEmbeddedDerivatives_51e55db9-94f3-4d8e-b28b-d31e122913d7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativesEmbeddedDerivatives"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_DerivativesEmbeddedDerivatives_51e55db9-94f3-4d8e-b28b-d31e122913d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_WarrantsAndRightsOutstandingPolicyPolicyTextBlock_3485fc0c-fa44-480a-bad9-29a6545d8647" xlink:href="huma-20250930.xsd#huma_WarrantsAndRightsOutstandingPolicyPolicyTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_huma_WarrantsAndRightsOutstandingPolicyPolicyTextBlock_3485fc0c-fa44-480a-bad9-29a6545d8647" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsPolicy_0c9f8448-92ef-41b2-ba83-4a6a0e68dc73" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationsPolicy"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_BusinessCombinationsPolicy_0c9f8448-92ef-41b2-ba83-4a6a0e68dc73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_46837426-dd3e-404a-8df3-29e7b849b033" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_58af09a9-070f-4b2c-8428-d860bc70f5b3" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_46837426-dd3e-404a-8df3-29e7b849b033" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_670f7571-a9c9-4ca4-9753-18190776eb6f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_cea39afd-8b70-4f74-8598-4f25b5de7257" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_670f7571-a9c9-4ca4-9753-18190776eb6f" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_cea39afd-8b70-4f74-8598-4f25b5de7257" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_d35bd077-41f1-45a4-8232-0d6c2931a334" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_670f7571-a9c9-4ca4-9753-18190776eb6f" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_d35bd077-41f1-45a4-8232-0d6c2931a334" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_64f6691b-6019-4136-b1ef-ec1bf2f5fde8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_670f7571-a9c9-4ca4-9753-18190776eb6f" xlink:to="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_64f6691b-6019-4136-b1ef-ec1bf2f5fde8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_7bb471be-50d0-48f0-9578-5a3d8759ce1e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_670f7571-a9c9-4ca4-9753-18190776eb6f" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_7bb471be-50d0-48f0-9578-5a3d8759ce1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/FairValueMeasurementsTables" xlink:type="simple" xlink:href="huma-20250930.xsd#FairValueMeasurementsTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_a724c3a0-01d7-4b40-8448-6f98f47de36b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTableTextBlock_18841f77-0882-4536-ad10-c8f91ec6360b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_a724c3a0-01d7-4b40-8448-6f98f47de36b" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTableTextBlock_18841f77-0882-4536-ad10-c8f91ec6360b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_f9c4038e-ecb1-4c8f-a0a2-9691b07ed004" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_a724c3a0-01d7-4b40-8448-6f98f47de36b" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_f9c4038e-ecb1-4c8f-a0a2-9691b07ed004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/InventoryTables" xlink:type="simple" xlink:href="huma-20250930.xsd#InventoryTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/InventoryTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_bfc739ae-ee1d-4a95-8438-229026b62eaf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_3ec2c89f-98ee-4027-8010-d2f960b76946" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_bfc739ae-ee1d-4a95-8438-229026b62eaf" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_3ec2c89f-98ee-4027-8010-d2f960b76946" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/PropertyandEquipmentNetTables" xlink:type="simple" xlink:href="huma-20250930.xsd#PropertyandEquipmentNetTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/PropertyandEquipmentNetTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_7b3c785c-c6cd-4092-b698-edcf8ee3b188" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_fe3698da-a2e5-4d3d-aa53-29bd6ac4eb49" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_7b3c785c-c6cd-4092-b698-edcf8ee3b188" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_fe3698da-a2e5-4d3d-aa53-29bd6ac4eb49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/AccruedExpensesTables" xlink:type="simple" xlink:href="huma-20250930.xsd#AccruedExpensesTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/AccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_e3c80999-20a5-453f-b4af-a76be3015c16" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_132b8206-b496-4e87-9a9b-96885b48e5c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_e3c80999-20a5-453f-b4af-a76be3015c16" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_132b8206-b496-4e87-9a9b-96885b48e5c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementTables" xlink:type="simple" xlink:href="huma-20250930.xsd#RevenueInterestPurchaseAgreementTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8d4c4a47-daf5-4714-a585-a9cc6ffc38a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_91e00f0f-d2a4-490b-8347-d24294427402" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8d4c4a47-daf5-4714-a585-a9cc6ffc38a7" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_91e00f0f-d2a4-490b-8347-d24294427402" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/LeasesTables" xlink:type="simple" xlink:href="huma-20250930.xsd#LeasesTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/LeasesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_9471b0ff-df75-426e-a574-fe1b7af79184" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_4d12cafc-10b6-4bb1-b36e-e24f5db5a695" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeaseCostTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_9471b0ff-df75-426e-a574-fe1b7af79184" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_4d12cafc-10b6-4bb1-b36e-e24f5db5a695" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_12b144dd-5e26-4dcf-8b5c-9457347f3f77" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_9471b0ff-df75-426e-a574-fe1b7af79184" xlink:to="loc_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_12b144dd-5e26-4dcf-8b5c-9457347f3f77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsTables" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_51736650-c088-4788-af56-b4ffb2d8007e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock_24284eb6-b198-43ca-9e1d-7d8480aa0e44" xlink:href="huma-20250930.xsd#huma_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_51736650-c088-4788-af56-b4ffb2d8007e" xlink:to="loc_huma_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock_24284eb6-b198-43ca-9e1d-7d8480aa0e44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_8a9bb2ee-7920-4a60-aad1-3af26c126917" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_51736650-c088-4788-af56-b4ffb2d8007e" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_8a9bb2ee-7920-4a60-aad1-3af26c126917" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock_46b4c329-4e4e-4e57-a1f5-66fecc5c724c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_51736650-c088-4788-af56-b4ffb2d8007e" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock_46b4c329-4e4e-4e57-a1f5-66fecc5c724c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensationTables" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensationTables"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_d12d3705-e359-47e3-ade4-d75093c62846" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_89686809-e017-4b20-a244-8332ffb70611" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_d12d3705-e359-47e3-ade4-d75093c62846" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_89686809-e017-4b20-a244-8332ffb70611" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_c5257448-55b6-465f-b034-00ea56a420c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_d12d3705-e359-47e3-ade4-d75093c62846" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_c5257448-55b6-465f-b034-00ea56a420c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_6250d332-f395-4595-b42e-fbbf8e7d80dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_d12d3705-e359-47e3-ade4-d75093c62846" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_6250d332-f395-4595-b42e-fbbf8e7d80dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#OrganizationandDescriptionofBusinessDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_012dbc38-d1cf-4f8a-923b-e0832da63139" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_012dbc38-d1cf-4f8a-923b-e0832da63139" xlink:to="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_cc7cdfd8-721a-4324-a108-fb5cd4ece252" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:to="loc_us-gaap_DebtInstrumentAxis_cc7cdfd8-721a-4324-a108-fb5cd4ece252" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_84a478b6-b651-4086-a05d-21ba506d0722" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_cc7cdfd8-721a-4324-a108-fb5cd4ece252" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_84a478b6-b651-4086-a05d-21ba506d0722" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestPurchaseAgreementMember_9600d39d-95d3-4adc-b283-a7ba35b5f133" xlink:href="huma-20250930.xsd#huma_RevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_84a478b6-b651-4086-a05d-21ba506d0722" xlink:to="loc_huma_RevenueInterestPurchaseAgreementMember_9600d39d-95d3-4adc-b283-a7ba35b5f133" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_d3603320-57e5-47b5-a94c-8aaf81dfdc05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_d3603320-57e5-47b5-a94c-8aaf81dfdc05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_2435950c-bb25-4c49-bed6-7c60438a8030" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_d3603320-57e5-47b5-a94c-8aaf81dfdc05" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_2435950c-bb25-4c49-bed6-7c60438a8030" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_d5db37f6-62ae-4b2c-ba04-4e66ddc61b73" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_2435950c-bb25-4c49-bed6-7c60438a8030" xlink:to="loc_huma_EquityLineFinancingMember_d5db37f6-62ae-4b2c-ba04-4e66ddc61b73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ATMFacilityMember_afe42178-d651-4a01-be30-bd1b58ac996f" xlink:href="huma-20250930.xsd#huma_ATMFacilityMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_2435950c-bb25-4c49-bed6-7c60438a8030" xlink:to="loc_huma_ATMFacilityMember_afe42178-d651-4a01-be30-bd1b58ac996f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_0d069e06-c0e2-48dd-9109-429ce1a0ec23" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_0d069e06-c0e2-48dd-9109-429ce1a0ec23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_7eb040e2-5a8c-44e4-b564-6de46fea1391" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_0d069e06-c0e2-48dd-9109-429ce1a0ec23" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_7eb040e2-5a8c-44e4-b564-6de46fea1391" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_a5d9968a-dce9-4b5e-8369-36805a9f9a9f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7eb040e2-5a8c-44e4-b564-6de46fea1391" xlink:to="loc_us-gaap_UnsecuredDebtMember_a5d9968a-dce9-4b5e-8369-36805a9f9a9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetTable_579af36f-b21b-40bd-bc83-e2d44ba21663" xlink:to="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_728c46dd-2c6a-437c-9374-0f993cae9258" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_728c46dd-2c6a-437c-9374-0f993cae9258" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_7c5ed5a9-968f-43f5-a4c1-331d82e2f91d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_OperatingIncomeLoss_7c5ed5a9-968f-43f5-a4c1-331d82e2f91d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_069f1037-43ac-4114-b53f-d72e4d74ea20" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_069f1037-43ac-4114-b53f-d72e4d74ea20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_NumberOfPurchasers_7e328029-387a-4e01-b002-d470cdafe6b6" xlink:href="huma-20250930.xsd#huma_NumberOfPurchasers"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_NumberOfPurchasers_7e328029-387a-4e01-b002-d470cdafe6b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_fdc39e31-44d7-4092-a24a-49490bde98ed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_LongTermDebt_fdc39e31-44d7-4092-a24a-49490bde98ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralToBeFunded_e04ec04d-0abb-4660-a84b-00f7079467e1" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralToBeFunded"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_ContingentCashCollateralToBeFunded_e04ec04d-0abb-4660-a84b-00f7079467e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_410162fd-f605-4348-8175-6a296b4806a3" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_410162fd-f605-4348-8175-6a296b4806a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralFunded_38d40f87-2b1e-44de-8037-6db207e16eaf" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralFunded"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_ContingentCashCollateralFunded_38d40f87-2b1e-44de-8037-6db207e16eaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_11cfb202-b94e-4d0f-b76d-318ee552816b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_11cfb202-b94e-4d0f-b76d-318ee552816b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashNoncurrent_f568be1f-963e-4aef-b42f-5a1059e7be0b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashNoncurrent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_RestrictedCashNoncurrent_f568be1f-963e-4aef-b42f-5a1059e7be0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_aacbe324-8a69-4c43-aa42-c1f236b8825b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_aacbe324-8a69-4c43-aa42-c1f236b8825b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_6c83710d-453b-459e-a87e-a740a2d26262" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountAuthorizedValue"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_6c83710d-453b-459e-a87e-a740a2d26262" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementTerm_69fbc9e9-0569-4002-abb0-ec2743056c0c" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementTerm"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_CommonStockPurchaseAgreementTerm_69fbc9e9-0569-4002-abb0-ec2743056c0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountRemaining_2dc6687e-bdee-4c4c-b860-880052027396" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountRemaining"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountRemaining_2dc6687e-bdee-4c4c-b860-880052027396" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_39dca551-13d7-4612-ab78-17f8dafe1a1b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_39dca551-13d7-4612-ab78-17f8dafe1a1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_15bc8e3e-6e39-4c79-8cc6-80dbef06bb05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationLessThanWhollyOwnedSubsidiaryParentOwnershipInterestEffectsOfChangesNetLineItems_29520e14-0ea2-4be2-a96d-ea3c140674be" xlink:to="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_15bc8e3e-6e39-4c79-8cc6-80dbef06bb05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesSegmentsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesSegmentsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesSegmentsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_59ceb81e-59d9-45a9-91e1-14815debd28f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfReportableSegments_b2fc6179-44a7-42c4-819d-dd76036274cf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NumberOfReportableSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_59ceb81e-59d9-45a9-91e1-14815debd28f" xlink:to="loc_us-gaap_NumberOfReportableSegments_b2fc6179-44a7-42c4-819d-dd76036274cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_3efdc10b-4b3a-45c9-adff-8a72a564ff71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_59ceb81e-59d9-45a9-91e1-14815debd28f" xlink:to="loc_us-gaap_NumberOfOperatingSegments_3efdc10b-4b3a-45c9-adff-8a72a564ff71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesResearchandDevelopmentDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesResearchandDevelopmentDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesResearchandDevelopmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_97fde464-019c-4752-a980-df20c9dfd423" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740eaecf-31da-4d08-a212-da4ec0ce2857" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_97fde464-019c-4752-a980-df20c9dfd423" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740eaecf-31da-4d08-a212-da4ec0ce2857" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_3d2d9980-397c-4b75-a1f5-e34ca7727ba2" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740eaecf-31da-4d08-a212-da4ec0ce2857" xlink:to="loc_srt_ProductOrServiceAxis_3d2d9980-397c-4b75-a1f5-e34ca7727ba2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_3f5dc90f-2f15-4e65-9da3-60010d197405" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_3d2d9980-397c-4b75-a1f5-e34ca7727ba2" xlink:to="loc_srt_ProductsAndServicesDomain_3f5dc90f-2f15-4e65-9da3-60010d197405" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DirectExpensesMember_344fdee6-996a-44bd-afa4-d04771745b38" xlink:href="huma-20250930.xsd#huma_DirectExpensesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3f5dc90f-2f15-4e65-9da3-60010d197405" xlink:to="loc_huma_DirectExpensesMember_344fdee6-996a-44bd-afa4-d04771745b38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_VascularTraumaMember_47d02d4c-dfc4-467a-bb4b-613339c06930" xlink:href="huma-20250930.xsd#huma_VascularTraumaMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_DirectExpensesMember_344fdee6-996a-44bd-afa4-d04771745b38" xlink:to="loc_huma_VascularTraumaMember_47d02d4c-dfc4-467a-bb4b-613339c06930" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_AVAccessMember_5e5465ba-9432-45a7-b3f3-d897a23e3e81" xlink:href="huma-20250930.xsd#huma_AVAccessMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_DirectExpensesMember_344fdee6-996a-44bd-afa4-d04771745b38" xlink:to="loc_huma_AVAccessMember_5e5465ba-9432-45a7-b3f3-d897a23e3e81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PADMember_a54d2cec-e6c3-4dec-b907-c7f85ff8847a" xlink:href="huma-20250930.xsd#huma_PADMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_DirectExpensesMember_344fdee6-996a-44bd-afa4-d04771745b38" xlink:to="loc_huma_PADMember_a54d2cec-e6c3-4dec-b907-c7f85ff8847a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:href="huma-20250930.xsd#huma_UnallocatedExpensesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3f5dc90f-2f15-4e65-9da3-60010d197405" xlink:to="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ExternalServicesMember_48844a06-aad5-4135-b04b-cc17cf5e4a66" xlink:href="huma-20250930.xsd#huma_ExternalServicesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:to="loc_huma_ExternalServicesMember_48844a06-aad5-4135-b04b-cc17cf5e4a66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MaterialsAndSuppliesMember_b94b6df1-29e9-4ede-a1c8-f273bdc0fed3" xlink:href="huma-20250930.xsd#huma_MaterialsAndSuppliesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:to="loc_huma_MaterialsAndSuppliesMember_b94b6df1-29e9-4ede-a1c8-f273bdc0fed3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PayrollAndPersonnelExpensesMember_6ab52555-d506-4fcf-91f5-1d6c900614c9" xlink:href="huma-20250930.xsd#huma_PayrollAndPersonnelExpensesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:to="loc_huma_PayrollAndPersonnelExpensesMember_6ab52555-d506-4fcf-91f5-1d6c900614c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OtherResearchAndDevelopmentMember_4c50ccff-9bbf-4dfa-bcfa-bab031f4f755" xlink:href="huma-20250930.xsd#huma_OtherResearchAndDevelopmentMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_UnallocatedExpensesMember_91b49f04-3899-415f-9bc4-19938bacd809" xlink:to="loc_huma_OtherResearchAndDevelopmentMember_4c50ccff-9bbf-4dfa-bcfa-bab031f4f755" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_c12684e7-3f45-463a-8a88-53e8aa2ae72e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740eaecf-31da-4d08-a212-da4ec0ce2857" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_c12684e7-3f45-463a-8a88-53e8aa2ae72e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_1902bb82-30ad-436f-a6a1-8f2c8e5c17cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_c12684e7-3f45-463a-8a88-53e8aa2ae72e" xlink:to="loc_us-gaap_SegmentDomain_1902bb82-30ad-436f-a6a1-8f2c8e5c17cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReportableSegmentMember_86006390-c26e-46dd-ac87-ed638f8d5d11" xlink:href="huma-20250930.xsd#huma_ReportableSegmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_1902bb82-30ad-436f-a6a1-8f2c8e5c17cc" xlink:to="loc_huma_ReportableSegmentMember_86006390-c26e-46dd-ac87-ed638f8d5d11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_c1f01c45-01ef-4bea-8bf1-e57fba679a5d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingInformationLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740eaecf-31da-4d08-a212-da4ec0ce2857" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_c1f01c45-01ef-4bea-8bf1-e57fba679a5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_57aee0ae-285d-4217-9dc3-9a8779d33147" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_c1f01c45-01ef-4bea-8bf1-e57fba679a5d" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_57aee0ae-285d-4217-9dc3-9a8779d33147" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesNonCashOperatingExpensesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesNonCashOperatingExpensesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesNonCashOperatingExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_bff24799-91bc-4a6f-90ac-9972215c69fb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_81a39cfa-e46f-4e16-9aa1-a2fdf9ed391b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_bff24799-91bc-4a6f-90ac-9972215c69fb" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_81a39cfa-e46f-4e16-9aa1-a2fdf9ed391b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_c74725c0-0586-4c11-9430-4d08d188351b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_81a39cfa-e46f-4e16-9aa1-a2fdf9ed391b" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_c74725c0-0586-4c11-9430-4d08d188351b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_1b2cb789-fe02-4040-8353-0a2f9a6d95e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_c74725c0-0586-4c11-9430-4d08d188351b" xlink:to="loc_us-gaap_SegmentDomain_1b2cb789-fe02-4040-8353-0a2f9a6d95e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReportableSegmentMember_9ef77119-1854-408b-9bd2-a7a50f21068f" xlink:href="huma-20250930.xsd#huma_ReportableSegmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_1b2cb789-fe02-4040-8353-0a2f9a6d95e5" xlink:to="loc_huma_ReportableSegmentMember_9ef77119-1854-408b-9bd2-a7a50f21068f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_282a3a52-0ae8-48ba-8029-981cfc0abe91" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingInformationLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_81a39cfa-e46f-4e16-9aa1-a2fdf9ed391b" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_282a3a52-0ae8-48ba-8029-981cfc0abe91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_1ccfd781-e2c5-4826-85fc-012b15bacd08" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_282a3a52-0ae8-48ba-8029-981cfc0abe91" xlink:to="loc_us-gaap_Depreciation_1ccfd781-e2c5-4826-85fc-012b15bacd08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_1ee06af3-cebb-41a5-b917-3e1037581d99" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_282a3a52-0ae8-48ba-8029-981cfc0abe91" xlink:to="loc_us-gaap_ShareBasedCompensation_1ee06af3-cebb-41a5-b917-3e1037581d99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesInventoryNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesInventoryNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesInventoryNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_ce3e4f2b-05f4-459b-8174-d2ab3fe613c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryCurrentTable_6d4b5afc-ba39-4ff8-bf60-ec6b9f4f0370" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryCurrentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_ce3e4f2b-05f4-459b-8174-d2ab3fe613c1" xlink:to="loc_us-gaap_InventoryCurrentTable_6d4b5afc-ba39-4ff8-bf60-ec6b9f4f0370" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_c5e71397-9358-4b32-b00f-8eeedac8051e" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryCurrentTable_6d4b5afc-ba39-4ff8-bf60-ec6b9f4f0370" xlink:to="loc_srt_ProductOrServiceAxis_c5e71397-9358-4b32-b00f-8eeedac8051e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_1e307f2b-f595-4c5c-80ab-ac16d91778d4" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_c5e71397-9358-4b32-b00f-8eeedac8051e" xlink:to="loc_srt_ProductsAndServicesDomain_1e307f2b-f595-4c5c-80ab-ac16d91778d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_e9ef1fec-bb2c-40bd-9d41-a47cb1c83b14" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_1e307f2b-f595-4c5c-80ab-ac16d91778d4" xlink:to="loc_us-gaap_ProductMember_e9ef1fec-bb2c-40bd-9d41-a47cb1c83b14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryLineItems_a8789644-1979-42e8-a339-9fc3558bfd10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryCurrentTable_6d4b5afc-ba39-4ff8-bf60-ec6b9f4f0370" xlink:to="loc_us-gaap_InventoryLineItems_a8789644-1979-42e8-a339-9fc3558bfd10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_de37c846-1fa8-4e27-9af4-0c39a0f8a83f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryLineItems_a8789644-1979-42e8-a339-9fc3558bfd10" xlink:to="loc_us-gaap_InventoryNet_de37c846-1fa8-4e27-9af4-0c39a0f8a83f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryValuationReserves_bcc3cbeb-f2e6-4be4-9aa1-01623570c3c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryValuationReserves"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryLineItems_a8789644-1979-42e8-a339-9fc3558bfd10" xlink:to="loc_us-gaap_InventoryValuationReserves_bcc3cbeb-f2e6-4be4-9aa1-01623570c3c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_28639e10-a0fa-4d2e-9738-88982b411ade" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryLineItems_a8789644-1979-42e8-a339-9fc3558bfd10" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_28639e10-a0fa-4d2e-9738-88982b411ade" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRevenueRecognitionNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesRevenueRecognitionNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRevenueRecognitionNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_c6d3aa93-3b6e-4d9e-9159-5dc8dc501f34" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_33c4f016-4edb-4a6b-850a-5c54d2eb9f05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_c6d3aa93-3b6e-4d9e-9159-5dc8dc501f34" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_33c4f016-4edb-4a6b-850a-5c54d2eb9f05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_9808eb96-f885-40d2-84f9-f88b1d7ffd4a" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_33c4f016-4edb-4a6b-850a-5c54d2eb9f05" xlink:to="loc_srt_ProductOrServiceAxis_9808eb96-f885-40d2-84f9-f88b1d7ffd4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_3d98cf30-ffec-486e-a1f6-9e1c0ad32478" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_9808eb96-f885-40d2-84f9-f88b1d7ffd4a" xlink:to="loc_srt_ProductsAndServicesDomain_3d98cf30-ffec-486e-a1f6-9e1c0ad32478" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_45606132-4553-4fbe-90a4-b44d93ef2919" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3d98cf30-ffec-486e-a1f6-9e1c0ad32478" xlink:to="loc_us-gaap_ProductMember_45606132-4553-4fbe-90a4-b44d93ef2919" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_88c767d9-cf21-402a-89b3-0eec26976dd5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3d98cf30-ffec-486e-a1f6-9e1c0ad32478" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_88c767d9-cf21-402a-89b3-0eec26976dd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_a338105a-6d59-44aa-b1f6-a999679d4085" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_33c4f016-4edb-4a6b-850a-5c54d2eb9f05" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_a338105a-6d59-44aa-b1f6-a999679d4085" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_0baa4514-c1e5-40bb-b7ec-e7f1f5662599" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_a338105a-6d59-44aa-b1f6-a999679d4085" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_0baa4514-c1e5-40bb-b7ec-e7f1f5662599" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRestrictedCashNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesRestrictedCashNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRestrictedCashNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_c4fd8ede-55bd-4fd8-9407-3f5a84650277" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_c4fd8ede-55bd-4fd8-9407-3f5a84650277" xlink:to="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_4121e26d-40b3-412b-aba5-ea83dcb4b5e8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:to="loc_us-gaap_DebtInstrumentAxis_4121e26d-40b3-412b-aba5-ea83dcb4b5e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_a39d6826-e29d-42b3-8705-a3cb19001a50" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_4121e26d-40b3-412b-aba5-ea83dcb4b5e8" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_a39d6826-e29d-42b3-8705-a3cb19001a50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestPurchaseAgreementMember_dddef474-9fe6-482d-bd88-5218b7d17415" xlink:href="huma-20250930.xsd#huma_RevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_a39d6826-e29d-42b3-8705-a3cb19001a50" xlink:to="loc_huma_RevenueInterestPurchaseAgreementMember_dddef474-9fe6-482d-bd88-5218b7d17415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsAxis_25fa42f4-f6d5-4e98-87a2-db675e44cd57" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsAxis_25fa42f4-f6d5-4e98-87a2-db675e44cd57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6dd78d1a-7444-4e3f-bac9-a69ab17e2234" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsAxis_25fa42f4-f6d5-4e98-87a2-db675e44cd57" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6dd78d1a-7444-4e3f-bac9-a69ab17e2234" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositAccountMember_37082ed1-15f7-4b12-8ac3-754bb0128d0f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepositAccountMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6dd78d1a-7444-4e3f-bac9-a69ab17e2234" xlink:to="loc_us-gaap_DepositAccountMember_37082ed1-15f7-4b12-8ac3-754bb0128d0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_734763c2-34fb-423b-bf23-0eafe97f3f11" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_734763c2-34fb-423b-bf23-0eafe97f3f11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_8132a03f-8240-43f1-bd6a-a7450d0510f5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_734763c2-34fb-423b-bf23-0eafe97f3f11" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_8132a03f-8240-43f1-bd6a-a7450d0510f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_ebcd7a72-b833-4e89-ba61-4ed8cea228de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_8132a03f-8240-43f1-bd6a-a7450d0510f5" xlink:to="loc_us-gaap_UnsecuredDebtMember_ebcd7a72-b833-4e89-ba61-4ed8cea228de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_ad191c7d-452a-4d4a-925b-f5021de80058" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashNoncurrent_baba5f5f-038e-48a3-ba96-998628bd977e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashNoncurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:to="loc_us-gaap_RestrictedCashNoncurrent_baba5f5f-038e-48a3-ba96-998628bd977e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashCurrent_cefe54eb-c96a-4e38-9f47-0b7e822bcdab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:to="loc_us-gaap_RestrictedCashCurrent_cefe54eb-c96a-4e38-9f47-0b7e822bcdab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_9c5e81b2-04a9-4ed5-8eab-2b8991626221" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_9c5e81b2-04a9-4ed5-8eab-2b8991626221" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_7de4926a-6b43-40bd-8359-cf62515eaaea" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_1d3ef6ac-df98-4afd-913d-1d1ca02f9965" xlink:to="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_7de4926a-6b43-40bd-8359-cf62515eaaea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRestrictedCashDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesRestrictedCashDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesRestrictedCashDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_f3fde1c3-12a9-403b-92d5-a8de685e6ff0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_f5a927a7-926c-410a-a0d9-391ff61a038e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f3fde1c3-12a9-403b-92d5-a8de685e6ff0" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_f5a927a7-926c-410a-a0d9-391ff61a038e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashCurrent_f3fb1cae-e0d6-4808-89ad-5d8a98b7b72e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f3fde1c3-12a9-403b-92d5-a8de685e6ff0" xlink:to="loc_us-gaap_RestrictedCashCurrent_f3fb1cae-e0d6-4808-89ad-5d8a98b7b72e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashNoncurrent_6eca90c0-9450-4978-8f02-e4fa27b177c2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f3fde1c3-12a9-403b-92d5-a8de685e6ff0" xlink:to="loc_us-gaap_RestrictedCashNoncurrent_6eca90c0-9450-4978-8f02-e4fa27b177c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_caa8f17e-331d-47a5-9244-7bfb44de7d66" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f3fde1c3-12a9-403b-92d5-a8de685e6ff0" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_caa8f17e-331d-47a5-9244-7bfb44de7d66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedFromComputationDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedFromComputationDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedFromComputationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9d59cac8-6ae0-4c62-8daf-f266f69356f0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9d59cac8-6ae0-4c62-8daf-f266f69356f0" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_89ff5663-176b-4cd4-987d-f06d839058ef" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_89ff5663-176b-4cd4-987d-f06d839058ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_05381fa4-7b89-46d1-930c-f661f0b8789e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_89ff5663-176b-4cd4-987d-f06d839058ef" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_05381fa4-7b89-46d1-930c-f661f0b8789e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_1485eded-e2de-4265-99d4-01e7dc6eff69" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_05381fa4-7b89-46d1-930c-f661f0b8789e" xlink:to="loc_us-gaap_EmployeeStockOptionMember_1485eded-e2de-4265-99d4-01e7dc6eff69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_e132c3a2-82bb-47f3-82a4-6a7b6a0d69b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_05381fa4-7b89-46d1-930c-f661f0b8789e" xlink:to="loc_us-gaap_WarrantMember_e132c3a2-82bb-47f3-82a4-6a7b6a0d69b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SaleOfStockOptionMember_a7d9c55e-2450-4dbd-b9e0-6df0508737d5" xlink:href="huma-20250930.xsd#huma_SaleOfStockOptionMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_05381fa4-7b89-46d1-930c-f661f0b8789e" xlink:to="loc_huma_SaleOfStockOptionMember_a7d9c55e-2450-4dbd-b9e0-6df0508737d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_76a69d4c-cc23-4321-a8c0-56e2f599c531" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:to="loc_srt_CounterpartyNameAxis_76a69d4c-cc23-4321-a8c0-56e2f599c531" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_ac7a7c63-deb9-4a09-af75-b5b9523c3fc2" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_76a69d4c-cc23-4321-a8c0-56e2f599c531" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_ac7a7c63-deb9-4a09-af75-b5b9523c3fc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_d9dd4b29-a55e-4d26-81c3-673690dfd34c" xlink:href="huma-20250930.xsd#huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_ac7a7c63-deb9-4a09-af75-b5b9523c3fc2" xlink:to="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_d9dd4b29-a55e-4d26-81c3-673690dfd34c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_c4d8efcc-6768-4fe6-a135-0d703e82acd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:to="loc_us-gaap_DebtInstrumentAxis_c4d8efcc-6768-4fe6-a135-0d703e82acd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_9a44d9c3-c8ac-4690-9f35-5e0b67901042" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_c4d8efcc-6768-4fe6-a135-0d703e82acd1" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_9a44d9c3-c8ac-4690-9f35-5e0b67901042" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionPurchaseAgreementMember_8ecc7ac5-8507-40b9-a99b-15e3b9916fc7" xlink:href="huma-20250930.xsd#huma_OptionPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9a44d9c3-c8ac-4690-9f35-5e0b67901042" xlink:to="loc_huma_OptionPurchaseAgreementMember_8ecc7ac5-8507-40b9-a99b-15e3b9916fc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d81c9a40-def8-4733-abf2-5a766bc5b908" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_105e909a-e60c-4765-99a7-c5ec22ed9ed9" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d81c9a40-def8-4733-abf2-5a766bc5b908" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c095e533-1e58-4c79-b283-9f4228bce355" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d81c9a40-def8-4733-abf2-5a766bc5b908" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c095e533-1e58-4c79-b283-9f4228bce355" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityShares_13162f11-3c54-44fe-a381-847ade46a317" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityShares"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d81c9a40-def8-4733-abf2-5a766bc5b908" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityShares_13162f11-3c54-44fe-a381-847ade46a317" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementExercisePrice_3d10bd9b-bcdf-4e46-99f3-64e74de4b060" xlink:href="huma-20250930.xsd#huma_OptionAgreementExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d81c9a40-def8-4733-abf2-5a766bc5b908" xlink:to="loc_huma_OptionAgreementExercisePrice_3d10bd9b-bcdf-4e46-99f3-64e74de4b060" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/FairValueMeasurementsAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#FairValueMeasurementsAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/FairValueMeasurementsAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_e432b8cf-ffce-4dbe-91e4-9b0c95ed1339" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_e432b8cf-ffce-4dbe-91e4-9b0c95ed1339" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_71e5e1c0-be25-4da6-b0e6-2ec0b2bcaafc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_71e5e1c0-be25-4da6-b0e6-2ec0b2bcaafc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_2037cbe6-d21f-4b27-a55a-969ea69855f8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_71e5e1c0-be25-4da6-b0e6-2ec0b2bcaafc" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_2037cbe6-d21f-4b27-a55a-969ea69855f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_5946a7f9-ee6f-40ab-877f-2195bf3854ef" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_2037cbe6-d21f-4b27-a55a-969ea69855f8" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_5946a7f9-ee6f-40ab-877f-2195bf3854ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_62299378-f7a3-4ff9-8f8c-bde4e5dc2d63" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_62299378-f7a3-4ff9-8f8c-bde4e5dc2d63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6ae7138c-8e81-4612-a9fc-136e54e6f797" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_62299378-f7a3-4ff9-8f8c-bde4e5dc2d63" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6ae7138c-8e81-4612-a9fc-136e54e6f797" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_b30456ae-73cf-4661-9b0c-0db4db97854b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_6ae7138c-8e81-4612-a9fc-136e54e6f797" xlink:to="loc_us-gaap_MoneyMarketFundsMember_b30456ae-73cf-4661-9b0c-0db4db97854b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_a861561e-167d-4ce6-beae-e413b0d2f544" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_a861561e-167d-4ce6-beae-e413b0d2f544" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5331148a-bf8c-4e6c-8fe7-b4eff4e7a0e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_a861561e-167d-4ce6-beae-e413b0d2f544" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5331148a-bf8c-4e6c-8fe7-b4eff4e7a0e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_2d2c01e0-6c57-4be3-837c-652927f7eb6c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5331148a-bf8c-4e6c-8fe7-b4eff4e7a0e3" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_2d2c01e0-6c57-4be3-837c-652927f7eb6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_081e036f-e459-4940-9c19-2a80a644f2d0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5331148a-bf8c-4e6c-8fe7-b4eff4e7a0e3" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_081e036f-e459-4940-9c19-2a80a644f2d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_4c0984cd-d439-4a0e-9bbf-364236e9428d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5331148a-bf8c-4e6c-8fe7-b4eff4e7a0e3" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_4c0984cd-d439-4a0e-9bbf-364236e9428d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_cf11ec81-2e58-4d02-93b5-b7ab90f0fe56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_cf11ec81-2e58-4d02-93b5-b7ab90f0fe56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_d69c7b1b-2b21-44ad-9830-53d5a64c4469" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_cf11ec81-2e58-4d02-93b5-b7ab90f0fe56" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_d69c7b1b-2b21-44ad-9830-53d5a64c4469" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_7976959c-6790-4fb8-98e4-9c76cdf2883e" xlink:href="huma-20250930.xsd#huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_d69c7b1b-2b21-44ad-9830-53d5a64c4469" xlink:to="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_7976959c-6790-4fb8-98e4-9c76cdf2883e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockOptionMember_330d235e-6c99-481f-9aa9-3ef3138047dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockOptionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_d69c7b1b-2b21-44ad-9830-53d5a64c4469" xlink:to="loc_us-gaap_StockOptionMember_330d235e-6c99-481f-9aa9-3ef3138047dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_JDRFAgreementMember_ac1c90e9-1061-489f-ab77-472f103f9b88" xlink:href="huma-20250930.xsd#huma_JDRFAgreementMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_d69c7b1b-2b21-44ad-9830-53d5a64c4469" xlink:to="loc_huma_JDRFAgreementMember_ac1c90e9-1061-489f-ab77-472f103f9b88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_2c338ed8-6f3b-46ab-858d-b36bc99e1b3a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_2c338ed8-6f3b-46ab-858d-b36bc99e1b3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_2d020066-172e-40d0-becf-19ecc6e8af5b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_2c338ed8-6f3b-46ab-858d-b36bc99e1b3a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_2d020066-172e-40d0-becf-19ecc6e8af5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PrivatePlacementWarrantsMember_36f30fa2-29cd-442c-8d1b-7145caf2f2a2" xlink:href="huma-20250930.xsd#huma_PrivatePlacementWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_2d020066-172e-40d0-becf-19ecc6e8af5b" xlink:to="loc_huma_PrivatePlacementWarrantsMember_36f30fa2-29cd-442c-8d1b-7145caf2f2a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_33711e31-781c-43b8-943b-ca8e2ee6c0b5" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_2d020066-172e-40d0-becf-19ecc6e8af5b" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_33711e31-781c-43b8-943b-ca8e2ee6c0b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_f604c4c0-fbbf-4ebb-bdcb-3600b8a331a1" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_2d020066-172e-40d0-becf-19ecc6e8af5b" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_f604c4c0-fbbf-4ebb-bdcb-3600b8a331a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_dd4bdf57-f012-4154-a646-079287e20f8d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_949e4a14-f6ec-4021-ae27-bd49d4f40094" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_dd4bdf57-f012-4154-a646-079287e20f8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_20bf895e-4e9d-46c4-b6d5-5dcc035bfcb6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_dd4bdf57-f012-4154-a646-079287e20f8d" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_20bf895e-4e9d-46c4-b6d5-5dcc035bfcb6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_bc931021-1d9c-44b0-9e16-4fe0402187cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_20bf895e-4e9d-46c4-b6d5-5dcc035bfcb6" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_bc931021-1d9c-44b0-9e16-4fe0402187cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_310d78a2-1721-4c1f-a8b1-f5ca08250cfc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeAssets"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_20bf895e-4e9d-46c4-b6d5-5dcc035bfcb6" xlink:to="loc_us-gaap_DerivativeAssets_310d78a2-1721-4c1f-a8b1-f5ca08250cfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_97a8d48b-422d-4477-ab23-03e0282c4c13" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_20bf895e-4e9d-46c4-b6d5-5dcc035bfcb6" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_97a8d48b-422d-4477-ab23-03e0282c4c13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_dd4bdf57-f012-4154-a646-079287e20f8d" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_e61dba97-92e0-482a-8000-49ee4b5b1840" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_e61dba97-92e0-482a-8000-49ee4b5b1840" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_4aa18c3c-b9c1-4775-9eab-7e0557b311e9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeLiabilities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:to="loc_us-gaap_DerivativeLiabilities_4aa18c3c-b9c1-4775-9eab-7e0557b311e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_57a85a5f-896d-4f0e-a464-5c068b570c7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_57a85a5f-896d-4f0e-a464-5c068b570c7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_80fad2c0-fa1e-4086-b11c-5d240400dd5c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosure"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b34f5aa8-4654-4210-9e5c-f155e1c97de6" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_80fad2c0-fa1e-4086-b11c-5d240400dd5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#FairValueMeasurementsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_eb12db30-3e07-4123-975b-d9c72d8cf353" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_eb12db30-3e07-4123-975b-d9c72d8cf353" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_892d8185-0926-4581-8448-7b0704b4ebb7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_StatementClassOfStockAxis_892d8185-0926-4581-8448-7b0704b4ebb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_ac8da0da-d866-435c-bb8f-60bf0e0a0e58" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_892d8185-0926-4581-8448-7b0704b4ebb7" xlink:to="loc_us-gaap_ClassOfStockDomain_ac8da0da-d866-435c-bb8f-60bf0e0a0e58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommitmentSharesMember_d1cc9838-1c07-4077-bd56-ede8b1ee32a8" xlink:href="huma-20250930.xsd#huma_CommitmentSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_ac8da0da-d866-435c-bb8f-60bf0e0a0e58" xlink:to="loc_huma_CommitmentSharesMember_d1cc9838-1c07-4077-bd56-ede8b1ee32a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_5ee5d462-e28a-423a-823f-c1f73eb8a402" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_5ee5d462-e28a-423a-823f-c1f73eb8a402" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4d7c6716-c9aa-40bc-8050-572fc1ab9154" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_5ee5d462-e28a-423a-823f-c1f73eb8a402" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4d7c6716-c9aa-40bc-8050-572fc1ab9154" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_20353a29-56fd-4b18-8f7c-a8dff6a1747f" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4d7c6716-c9aa-40bc-8050-572fc1ab9154" xlink:to="loc_huma_EquityLineFinancingMember_20353a29-56fd-4b18-8f7c-a8dff6a1747f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_92efb770-9601-4b93-a754-f65b4b36b4bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_92efb770-9601-4b93-a754-f65b4b36b4bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_100328eb-37e4-443b-9637-7aba77521f7a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_92efb770-9601-4b93-a754-f65b4b36b4bb" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_100328eb-37e4-443b-9637-7aba77521f7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_da14300c-bfae-446f-8d2e-ed896d68b0bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_100328eb-37e4-443b-9637-7aba77521f7a" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_da14300c-bfae-446f-8d2e-ed896d68b0bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_d4b4ed95-e56a-44ad-b9de-7df4e29e7875" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_d4b4ed95-e56a-44ad-b9de-7df4e29e7875" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_b66245de-403f-488e-8718-b5c0471c8d80" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_d4b4ed95-e56a-44ad-b9de-7df4e29e7875" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_b66245de-403f-488e-8718-b5c0471c8d80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentEarnoutLiabilityMember_71d75869-b8de-48f1-8c03-e5010ebcaf82" xlink:href="huma-20250930.xsd#huma_ContingentEarnoutLiabilityMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_b66245de-403f-488e-8718-b5c0471c8d80" xlink:to="loc_huma_ContingentEarnoutLiabilityMember_71d75869-b8de-48f1-8c03-e5010ebcaf82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_eb445885-5cb0-4bb2-9a54-d0297d8f94a6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_eb445885-5cb0-4bb2-9a54-d0297d8f94a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_132ad6bb-b9c7-4dad-94c9-e7f8d28d39b1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_eb445885-5cb0-4bb2-9a54-d0297d8f94a6" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_132ad6bb-b9c7-4dad-94c9-e7f8d28d39b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_046380c0-6699-4e63-8263-7e97afce0937" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_132ad6bb-b9c7-4dad-94c9-e7f8d28d39b1" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_046380c0-6699-4e63-8263-7e97afce0937" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MeasurementInputRevenueForecastDiscountRateMember_e10eb5c5-99a2-40a2-83cb-72134dbda530" xlink:href="huma-20250930.xsd#huma_MeasurementInputRevenueForecastDiscountRateMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_132ad6bb-b9c7-4dad-94c9-e7f8d28d39b1" xlink:to="loc_huma_MeasurementInputRevenueForecastDiscountRateMember_e10eb5c5-99a2-40a2-83cb-72134dbda530" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MeasurementInputPayoffOfInstrumentDiscountRateMemberMember_d8332afa-e357-4595-be2e-d01615c674ab" xlink:href="huma-20250930.xsd#huma_MeasurementInputPayoffOfInstrumentDiscountRateMemberMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_132ad6bb-b9c7-4dad-94c9-e7f8d28d39b1" xlink:to="loc_huma_MeasurementInputPayoffOfInstrumentDiscountRateMemberMember_d8332afa-e357-4595-be2e-d01615c674ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_29f4b018-ee1e-4178-a8e0-2df4e5d0cdae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_FinancialInstrumentAxis_29f4b018-ee1e-4178-a8e0-2df4e5d0cdae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_b100a1cf-3d5b-416f-b35c-c942e204097b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_29f4b018-ee1e-4178-a8e0-2df4e5d0cdae" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_b100a1cf-3d5b-416f-b35c-c942e204097b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_10bec3d0-baba-4116-ac51-0083681d29ed" xlink:href="huma-20250930.xsd#huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_b100a1cf-3d5b-416f-b35c-c942e204097b" xlink:to="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_10bec3d0-baba-4116-ac51-0083681d29ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_cf24539b-d847-4938-93d3-5393476b1d96" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_4d9845e7-ea20-4900-b0ea-c205959c71e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_4d9845e7-ea20-4900-b0ea-c205959c71e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_5fb05aab-3959-4669-8d9c-5b5278d1f454" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountAuthorizedValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_5fb05aab-3959-4669-8d9c-5b5278d1f454" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_00e97bac-e6f1-405b-ba14-7c0e9973cddc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_us-gaap_DerivativeAssets_00e97bac-e6f1-405b-ba14-7c0e9973cddc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharePrice_b7ea2af2-cdbe-4087-9acc-5136748c16a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_us-gaap_SharePrice_b7ea2af2-cdbe-4087-9acc-5136748c16a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_1ee743ef-3b36-477f-ac72-addda0f413c9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_1ee743ef-3b36-477f-ac72-addda0f413c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmbeddedDerivativeLiabilityMeasurementInput_eb0df4f5-853c-483b-8757-3d608023e142" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmbeddedDerivativeLiabilityMeasurementInput"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5767b138-9cba-438a-bf32-23e4ed8e4bd5" xlink:to="loc_us-gaap_EmbeddedDerivativeLiabilityMeasurementInput_eb0df4f5-853c-483b-8757-3d608023e142" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/FairValueMeasurementsChangesinFairValueofLevel3FinancialInstrumentsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#FairValueMeasurementsChangesinFairValueofLevel3FinancialInstrumentsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/FairValueMeasurementsChangesinFairValueofLevel3FinancialInstrumentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_e8d4c71e-8e0a-4d4e-84e1-5a5cc34588b1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_fdd3aff2-1fbb-4ebc-a7a3-27b4afcf415b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_e8d4c71e-8e0a-4d4e-84e1-5a5cc34588b1" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_fdd3aff2-1fbb-4ebc-a7a3-27b4afcf415b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_4710816a-6163-43c2-b8d8-aa1064522e78" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_fdd3aff2-1fbb-4ebc-a7a3-27b4afcf415b" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_4710816a-6163-43c2-b8d8-aa1064522e78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_4710816a-6163-43c2-b8d8-aa1064522e78" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentEarnoutLiabilityMember_d2012db2-a377-460c-be52-265564694f18" xlink:href="huma-20250930.xsd#huma_ContingentEarnoutLiabilityMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:to="loc_huma_ContingentEarnoutLiabilityMember_d2012db2-a377-460c-be52-265564694f18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_b9fea27f-5d26-4baf-96fc-fc40a11d5a1d" xlink:href="huma-20250930.xsd#huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:to="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_b9fea27f-5d26-4baf-96fc-fc40a11d5a1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_40fd9572-9ad9-4d55-ae98-27ea241aea34" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_40fd9572-9ad9-4d55-ae98-27ea241aea34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_ab062649-505a-4559-8524-b8643c5dd6f6" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_ab062649-505a-4559-8524-b8643c5dd6f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PrivatePlacementWarrantsMember_459eb136-0551-46fd-a716-c9c09415d096" xlink:href="huma-20250930.xsd#huma_PrivatePlacementWarrantsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_afd920d2-d8ec-43f9-bd2c-ef5b64fb4fec" xlink:to="loc_huma_PrivatePlacementWarrantsMember_459eb136-0551-46fd-a716-c9c09415d096" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_f92761d9-4bb6-496b-b6ad-952c01506d4e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_fdd3aff2-1fbb-4ebc-a7a3-27b4afcf415b" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_f92761d9-4bb6-496b-b6ad-952c01506d4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_f92761d9-4bb6-496b-b6ad-952c01506d4e" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_888045f0-3925-421d-8332-9f2d4205d186" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_888045f0-3925-421d-8332-9f2d4205d186" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityIssues_6e902108-fc7e-4d7c-a330-da50327b74ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityIssues"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityIssues_6e902108-fc7e-4d7c-a330-da50327b74ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_74f75298-76dc-4cb9-9ebc-b7b7f6a13e60" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_74f75298-76dc-4cb9-9ebc-b7b7f6a13e60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_ebec0b7d-4a09-4d46-8e2f-1a5417116178" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_0fe2d0d3-70aa-4cec-a95e-bcefab894467" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_ebec0b7d-4a09-4d46-8e2f-1a5417116178" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/InventoryInventoryStatedatLowerCostsorNetRealizableValueDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#InventoryInventoryStatedatLowerCostsorNetRealizableValueDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/InventoryInventoryStatedatLowerCostsorNetRealizableValueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_92bcbfec-508e-4cad-b4b4-9364254c325e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsAndSuppliesNetOfReserves_db772e33-9249-41d5-b789-fe10e772bab9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryRawMaterialsAndSuppliesNetOfReserves"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_92bcbfec-508e-4cad-b4b4-9364254c325e" xlink:to="loc_us-gaap_InventoryRawMaterialsAndSuppliesNetOfReserves_db772e33-9249-41d5-b789-fe10e772bab9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_64ed4e9f-8d3e-4249-b615-80b2380d5edc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_92bcbfec-508e-4cad-b4b4-9364254c325e" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_64ed4e9f-8d3e-4249-b615-80b2380d5edc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_654812d8-a004-450f-b9d8-cdf569958e2b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_92bcbfec-508e-4cad-b4b4-9364254c325e" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_654812d8-a004-450f-b9d8-cdf569958e2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_44487bd5-0f1f-4477-9bad-155c265afdec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_92bcbfec-508e-4cad-b4b4-9364254c325e" xlink:to="loc_us-gaap_InventoryNet_44487bd5-0f1f-4477-9bad-155c265afdec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/InventoryNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#InventoryNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/InventoryNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_d3570794-b9fd-4d82-a225-e3d7be64722a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_7e1b1679-3fd9-43d4-8a97-1df0b6d25d38" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_d3570794-b9fd-4d82-a225-e3d7be64722a" xlink:to="loc_us-gaap_InventoryNet_7e1b1679-3fd9-43d4-8a97-1df0b6d25d38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/PropertyandEquipmentNetPropertyPlantandEquipmentNetDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#PropertyandEquipmentNetPropertyPlantandEquipmentNetDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/PropertyandEquipmentNetPropertyPlantandEquipmentNetDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_82d7635b-afda-4d79-8d44-e273c1c13e7a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_fdb7261c-fe72-42fe-a874-ede6904af43a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_82d7635b-afda-4d79-8d44-e273c1c13e7a" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_fdb7261c-fe72-42fe-a874-ede6904af43a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_9a74cf8c-a12b-4453-985d-f521b259764c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_fdb7261c-fe72-42fe-a874-ede6904af43a" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_9a74cf8c-a12b-4453-985d-f521b259764c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_9a74cf8c-a12b-4453-985d-f521b259764c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ScientificAndManufacturingEquipmentMember_58cb5aa9-11da-4024-aa75-21719b79227b" xlink:href="huma-20250930.xsd#huma_ScientificAndManufacturingEquipmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:to="loc_huma_ScientificAndManufacturingEquipmentMember_58cb5aa9-11da-4024-aa75-21719b79227b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComputerEquipmentMember_44cd3b2d-d3e3-46f3-928c-e8e83cf596f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComputerEquipmentMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:to="loc_us-gaap_ComputerEquipmentMember_44cd3b2d-d3e3-46f3-928c-e8e83cf596f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SoftwareDevelopmentMember_f5a6edb1-d225-43e1-925c-c70a030a60c0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SoftwareDevelopmentMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:to="loc_us-gaap_SoftwareDevelopmentMember_f5a6edb1-d225-43e1-925c-c70a030a60c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_4def015f-bf6d-44f7-81d6-9b372f7bf4b5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FurnitureAndFixturesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_4def015f-bf6d-44f7-81d6-9b372f7bf4b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_5414f084-c251-4331-b0f0-dd69ec5814b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeaseholdImprovementsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ca31b5cf-5f43-441b-b634-6178e56e502d" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_5414f084-c251-4331-b0f0-dd69ec5814b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_afac8a8c-ceae-4510-961f-11f4f5889000" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_fdb7261c-fe72-42fe-a874-ede6904af43a" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_afac8a8c-ceae-4510-961f-11f4f5889000" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_188fa567-c108-47c5-b021-25afd799869d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_afac8a8c-ceae-4510-961f-11f4f5889000" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_188fa567-c108-47c5-b021-25afd799869d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_7674fce7-14e9-46fe-8df0-49b4add7909d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_afac8a8c-ceae-4510-961f-11f4f5889000" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_7674fce7-14e9-46fe-8df0-49b4add7909d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_faf95933-eadf-4652-98fe-ec41d8fe2fc3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_afac8a8c-ceae-4510-961f-11f4f5889000" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_faf95933-eadf-4652-98fe-ec41d8fe2fc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/PropertyPlantandEquipmentNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#PropertyPlantandEquipmentNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/PropertyPlantandEquipmentNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_b88fddf2-e041-41e7-b0c1-aaeca6233e1f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_7904e7f8-e2ea-4209-aaa1-aa699888171c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_b88fddf2-e041-41e7-b0c1-aaeca6233e1f" xlink:to="loc_us-gaap_Depreciation_7904e7f8-e2ea-4209-aaa1-aa699888171c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/AccruedExpensesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#AccruedExpensesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/AccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_AccruedExternalResearchDevelopmentAndManufacturingCostsCurrent_8e660124-5045-4fc8-8b94-9cab0595120b" xlink:href="huma-20250930.xsd#huma_AccruedExternalResearchDevelopmentAndManufacturingCostsCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:to="loc_huma_AccruedExternalResearchDevelopmentAndManufacturingCostsCurrent_8e660124-5045-4fc8-8b94-9cab0595120b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_7a828c49-6dc1-453f-b327-e83a02d03646" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_7a828c49-6dc1-453f-b327-e83a02d03646" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_7b836f68-d604-437b-9c89-140ce2354bbc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedProfessionalFeesCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_7b836f68-d604-437b-9c89-140ce2354bbc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedRoyaltiesCurrent_3ab42932-9481-4d40-968f-a9cebeec58a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedRoyaltiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:to="loc_us-gaap_AccruedRoyaltiesCurrent_3ab42932-9481-4d40-968f-a9cebeec58a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_15e6cac6-78d6-49cc-91d1-d1cad747c159" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_ccc4094e-6646-4b9a-aa68-56874291d44c" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_15e6cac6-78d6-49cc-91d1-d1cad747c159" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#RevenueInterestPurchaseAgreementNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_ce167469-53a8-4f16-8537-8e46a8a998c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:href="huma-20250930.xsd#huma_RevenueInterestLiabilityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_ce167469-53a8-4f16-8537-8e46a8a998c3" xlink:to="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_485f4fad-8838-4573-8177-8daa0aa270f9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_us-gaap_DebtInstrumentAxis_485f4fad-8838-4573-8177-8daa0aa270f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_80e1faff-9d48-4c24-a12c-3c53fecb77ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_485f4fad-8838-4573-8177-8daa0aa270f9" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_80e1faff-9d48-4c24-a12c-3c53fecb77ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestPurchaseAgreementMember_6533e05f-ba79-423a-88e8-f0f1d626819c" xlink:href="huma-20250930.xsd#huma_RevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_80e1faff-9d48-4c24-a12c-3c53fecb77ac" xlink:to="loc_huma_RevenueInterestPurchaseAgreementMember_6533e05f-ba79-423a-88e8-f0f1d626819c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionPurchaseAgreementMember_48251e09-eaa8-4e2d-841f-19bfd7ccadd0" xlink:href="huma-20250930.xsd#huma_OptionPurchaseAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_80e1faff-9d48-4c24-a12c-3c53fecb77ac" xlink:to="loc_huma_OptionPurchaseAgreementMember_48251e09-eaa8-4e2d-841f-19bfd7ccadd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SubsequentInstallmentAxis_bbc127fe-bb7c-463f-8729-9bffc4885655" xlink:href="huma-20250930.xsd#huma_SubsequentInstallmentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_huma_SubsequentInstallmentAxis_bbc127fe-bb7c-463f-8729-9bffc4885655" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SubsequentInstallmentDomain_0fe61b22-90e8-40b3-bd83-b8677df38f56" xlink:href="huma-20250930.xsd#huma_SubsequentInstallmentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_SubsequentInstallmentAxis_bbc127fe-bb7c-463f-8729-9bffc4885655" xlink:to="loc_huma_SubsequentInstallmentDomain_0fe61b22-90e8-40b3-bd83-b8677df38f56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SubsequentInstallmentOneMember_79868d32-ac72-431b-95ce-584356202597" xlink:href="huma-20250930.xsd#huma_SubsequentInstallmentOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_SubsequentInstallmentDomain_0fe61b22-90e8-40b3-bd83-b8677df38f56" xlink:to="loc_huma_SubsequentInstallmentOneMember_79868d32-ac72-431b-95ce-584356202597" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionPeriodAxis_237a175f-7087-481a-a38a-9b9b2215f889" xlink:href="huma-20250930.xsd#huma_OptionPeriodAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_huma_OptionPeriodAxis_237a175f-7087-481a-a38a-9b9b2215f889" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionPeriodDomain_f0fd94c3-9526-45ea-ac8b-d1ff08c8b30c" xlink:href="huma-20250930.xsd#huma_OptionPeriodDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_OptionPeriodAxis_237a175f-7087-481a-a38a-9b9b2215f889" xlink:to="loc_huma_OptionPeriodDomain_f0fd94c3-9526-45ea-ac8b-d1ff08c8b30c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PeriodTwoMember_ddc83d0e-a4dd-46df-94b3-429c8ccd6848" xlink:href="huma-20250930.xsd#huma_PeriodTwoMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_OptionPeriodDomain_f0fd94c3-9526-45ea-ac8b-d1ff08c8b30c" xlink:to="loc_huma_PeriodTwoMember_ddc83d0e-a4dd-46df-94b3-429c8ccd6848" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PeriodThreeMember_d72876a1-a509-48b3-80f7-ff13f127d644" xlink:href="huma-20250930.xsd#huma_PeriodThreeMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_OptionPeriodDomain_f0fd94c3-9526-45ea-ac8b-d1ff08c8b30c" xlink:to="loc_huma_PeriodThreeMember_d72876a1-a509-48b3-80f7-ff13f127d644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_754b6d76-9d4b-4301-b443-00757ce86198" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_754b6d76-9d4b-4301-b443-00757ce86198" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_c8a31c96-ed7d-4fe9-8c15-db519dc0c8bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_754b6d76-9d4b-4301-b443-00757ce86198" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_c8a31c96-ed7d-4fe9-8c15-db519dc0c8bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_4efbc159-5bad-41e2-92bf-144639e8b3dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_c8a31c96-ed7d-4fe9-8c15-db519dc0c8bf" xlink:to="loc_us-gaap_UnsecuredDebtMember_4efbc159-5bad-41e2-92bf-144639e8b3dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_915c1a9f-e82d-47fb-bb24-a06c4216774c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_915c1a9f-e82d-47fb-bb24-a06c4216774c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_38ecd98c-68b9-4416-bbfb-ae9aff9bc748" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_915c1a9f-e82d-47fb-bb24-a06c4216774c" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_38ecd98c-68b9-4416-bbfb-ae9aff9bc748" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockOptionMember_4607c45f-8c46-4a07-b667-2a3bc8f30a10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_38ecd98c-68b9-4416-bbfb-ae9aff9bc748" xlink:to="loc_us-gaap_StockOptionMember_4607c45f-8c46-4a07-b667-2a3bc8f30a10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_68764386-a8b7-4838-bf3b-f82c315b192e" xlink:href="huma-20250930.xsd#huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_38ecd98c-68b9-4416-bbfb-ae9aff9bc748" xlink:to="loc_huma_EmbeddedDerivativeFinancialInstrumentsRevenueInterestPurchaseAgreementMember_68764386-a8b7-4838-bf3b-f82c315b192e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_b122ac2c-63c1-4beb-b3dd-a1e31091fa53" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_b122ac2c-63c1-4beb-b3dd-a1e31091fa53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_81fea140-749f-45fc-925e-e598eb0dc081" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_b122ac2c-63c1-4beb-b3dd-a1e31091fa53" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_81fea140-749f-45fc-925e-e598eb0dc081" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_6b52f484-8c0f-400b-b507-62b018901db2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_81fea140-749f-45fc-925e-e598eb0dc081" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_6b52f484-8c0f-400b-b507-62b018901db2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_9d170723-38e6-4f31-baca-537ad37c2bd9" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_srt_ProductOrServiceAxis_9d170723-38e6-4f31-baca-537ad37c2bd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_4f1fe125-d7b1-4366-9aae-d35004f31a55" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_9d170723-38e6-4f31-baca-537ad37c2bd9" xlink:to="loc_srt_ProductsAndServicesDomain_4f1fe125-d7b1-4366-9aae-d35004f31a55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_cb37a185-87c3-4d20-a3b3-2d3a4e49f597" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_4f1fe125-d7b1-4366-9aae-d35004f31a55" xlink:to="loc_us-gaap_ProductMember_cb37a185-87c3-4d20-a3b3-2d3a4e49f597" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_0b05f481-1415-4e8b-85f0-143d896551d8" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_srt_CounterpartyNameAxis_0b05f481-1415-4e8b-85f0-143d896551d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_227c2a47-22b5-4b40-9891-5039be3399fc" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_0b05f481-1415-4e8b-85f0-143d896551d8" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_227c2a47-22b5-4b40-9891-5039be3399fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_1e351b7c-691c-43f6-9716-7c994842df8e" xlink:href="huma-20250930.xsd#huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_227c2a47-22b5-4b40-9891-5039be3399fc" xlink:to="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_1e351b7c-691c-43f6-9716-7c994842df8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:href="huma-20250930.xsd#huma_RevenueInterestLiabilityLineItems"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_a1a4fb72-3095-47de-95f2-44cebe8d20a6" xlink:to="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PurchaseAgreementTotalInvestmentAmount_a797fd1f-d7e6-4eac-bbb3-a15b3a653355" xlink:href="huma-20250930.xsd#huma_PurchaseAgreementTotalInvestmentAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PurchaseAgreementTotalInvestmentAmount_a797fd1f-d7e6-4eac-bbb3-a15b3a653355" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_UpfrontPaymentReceived_b944cc4d-05df-4b4b-a258-a247fe0754b8" xlink:href="huma-20250930.xsd#huma_UpfrontPaymentReceived"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_UpfrontPaymentReceived_b944cc4d-05df-4b4b-a258-a247fe0754b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PurchaseAgreementMilestonePaymentReceived_4e7c4187-f6d7-4eb7-9587-71f3c9a0e300" xlink:href="huma-20250930.xsd#huma_PurchaseAgreementMilestonePaymentReceived"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PurchaseAgreementMilestonePaymentReceived_4e7c4187-f6d7-4eb7-9587-71f3c9a0e300" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MilestonePaymentBorrowingCapacityAmountUndrawn_f4e5026f-e48e-4476-968a-40cbd3c7b888" xlink:href="huma-20250930.xsd#huma_MilestonePaymentBorrowingCapacityAmountUndrawn"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_MilestonePaymentBorrowingCapacityAmountUndrawn_f4e5026f-e48e-4476-968a-40cbd3c7b888" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RoyaltyPercentageOfAnnualNetSalesPayable_8591ead1-02ce-4b3f-936e-77b36c19f256" xlink:href="huma-20250930.xsd#huma_RoyaltyPercentageOfAnnualNetSalesPayable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_RoyaltyPercentageOfAnnualNetSalesPayable_8591ead1-02ce-4b3f-936e-77b36c19f256" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PercentageThresholdOfCumulativePurchaserPayments_4fdf12c4-afd3-4db6-8960-347592516cee" xlink:href="huma-20250930.xsd#huma_PercentageThresholdOfCumulativePurchaserPayments"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PercentageThresholdOfCumulativePurchaserPayments_4fdf12c4-afd3-4db6-8960-347592516cee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PercentageOfCumulativePurchaserPaymentsLessTotalRevenueInterestPaymentsDue_ed3d759f-2176-4acd-b1b9-539bd73a836e" xlink:href="huma-20250930.xsd#huma_PercentageOfCumulativePurchaserPaymentsLessTotalRevenueInterestPaymentsDue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PercentageOfCumulativePurchaserPaymentsLessTotalRevenueInterestPaymentsDue_ed3d759f-2176-4acd-b1b9-539bd73a836e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForDiscontinuanceOfRevenueInterestPayments_06a34003-e17b-46e5-b51d-21d22b5c8e44" xlink:href="huma-20250930.xsd#huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForDiscontinuanceOfRevenueInterestPayments"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForDiscontinuanceOfRevenueInterestPayments_06a34003-e17b-46e5-b51d-21d22b5c8e44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForTerminationOfPurchaseAgreement_0003e345-276e-4cf5-9ace-48d6ebcc3143" xlink:href="huma-20250930.xsd#huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForTerminationOfPurchaseAgreement"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PercentageThresholdOfCumulativePurchaserPaymentsRequiredForTerminationOfPurchaseAgreement_0003e345-276e-4cf5-9ace-48d6ebcc3143" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PercentageOfCumulativePurchaserPaymentsRepurchasePrice_8fd45faa-ee22-4591-ac04-574a7659742e" xlink:href="huma-20250930.xsd#huma_PercentageOfCumulativePurchaserPaymentsRepurchasePrice"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PercentageOfCumulativePurchaserPaymentsRepurchasePrice_8fd45faa-ee22-4591-ac04-574a7659742e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PurchaseAgreementDiscountedRepurchasePrice_32b2d873-c281-476f-bf99-37651236abcc" xlink:href="huma-20250930.xsd#huma_PurchaseAgreementDiscountedRepurchasePrice"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PurchaseAgreementDiscountedRepurchasePrice_32b2d873-c281-476f-bf99-37651236abcc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PurchaseAgreementDiscountedRepurchasePricePortionSatisfiedThroughIssuanceOfCommonStock_752caaf8-3906-4c27-bdee-7bf4b0234ce2" xlink:href="huma-20250930.xsd#huma_PurchaseAgreementDiscountedRepurchasePricePortionSatisfiedThroughIssuanceOfCommonStock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_PurchaseAgreementDiscountedRepurchasePricePortionSatisfiedThroughIssuanceOfCommonStock_752caaf8-3906-4c27-bdee-7bf4b0234ce2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralFunded_a2e6d946-1489-42a9-b930-8432c50ece1d" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralFunded"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_ContingentCashCollateralFunded_a2e6d946-1489-42a9-b930-8432c50ece1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralAgentConsentAndOtherRights_b9c2548f-0102-4fd6-a440-0296154ed443" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralAgentConsentAndOtherRights"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_ContingentCashCollateralAgentConsentAndOtherRights_b9c2548f-0102-4fd6-a440-0296154ed443" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_2d0547b5-caee-4d55-8765-ee7c54982da2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_2d0547b5-caee-4d55-8765-ee7c54982da2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_e1613bb4-6265-4ad8-820c-91116c6487bd" xlink:href="huma-20250930.xsd#huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_ContingentCashCollateralToBeFundedAgentConsentAndOtherRights_e1613bb4-6265-4ad8-820c-91116c6487bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashNoncurrent_59bc18e2-d2fb-468c-8cca-facd7fac4486" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCashNoncurrent"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_RestrictedCashNoncurrent_59bc18e2-d2fb-468c-8cca-facd7fac4486" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5e873a59-51ca-4aa9-87ad-6439cba6a70e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5e873a59-51ca-4aa9-87ad-6439cba6a70e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_0a33b3d6-fc3f-403d-931e-5009f024dffe" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeLiabilities"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_DerivativeLiabilities_0a33b3d6-fc3f-403d-931e-5009f024dffe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DebtInstrumentDebtDiscountRecordedInThePeriod_93134c92-7531-4f84-9490-dddfb12aef11" xlink:href="huma-20250930.xsd#huma_DebtInstrumentDebtDiscountRecordedInThePeriod"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_DebtInstrumentDebtDiscountRecordedInThePeriod_93134c92-7531-4f84-9490-dddfb12aef11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebt_833dd9b9-a894-415b-bb2d-5844ddf5d6b5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebt"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_UnsecuredDebt_833dd9b9-a894-415b-bb2d-5844ddf5d6b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtCurrent_40820623-06a0-432f-81ee-0583e08e0214" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtCurrent"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_UnsecuredDebtCurrent_40820623-06a0-432f-81ee-0583e08e0214" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_ebcbb7f5-f815-45bd-a0d4-2c079a961ca2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_ebcbb7f5-f815-45bd-a0d4-2c079a961ca2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_7a35cab6-9568-444e-a2ea-28f884fd6171" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_InterestExpenseDebt_7a35cab6-9568-444e-a2ea-28f884fd6171" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_59120941-3d1b-461e-aa92-cfa5a0bbfa41" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_59120941-3d1b-461e-aa92-cfa5a0bbfa41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_InterestExpenseDebtRevenueInterest_c094afd7-0d3b-4046-941e-b9a8f1291288" xlink:href="huma-20250930.xsd#huma_InterestExpenseDebtRevenueInterest"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_InterestExpenseDebtRevenueInterest_c094afd7-0d3b-4046-941e-b9a8f1291288" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_d19f3c28-e984-463c-9601-9f9b234ee61e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_us-gaap_LongTermDebt_d19f3c28-e984-463c-9601-9f9b234ee61e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementSharesAuthorizedForIssuanceValue_8935766e-6e1d-4119-aa4e-6ec0ec8e514a" xlink:href="huma-20250930.xsd#huma_OptionAgreementSharesAuthorizedForIssuanceValue"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_OptionAgreementSharesAuthorizedForIssuanceValue_8935766e-6e1d-4119-aa4e-6ec0ec8e514a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementExercisePrice_44b5bdba-552f-48bc-b1a8-e99a4244cdc3" xlink:href="huma-20250930.xsd#huma_OptionAgreementExercisePrice"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_OptionAgreementExercisePrice_44b5bdba-552f-48bc-b1a8-e99a4244cdc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementNumberOfDaysVolumeWeightedAveragePrice_c102b774-8040-4f12-af94-a6e13e5dccb8" xlink:href="huma-20250930.xsd#huma_OptionAgreementNumberOfDaysVolumeWeightedAveragePrice"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_OptionAgreementNumberOfDaysVolumeWeightedAveragePrice_c102b774-8040-4f12-af94-a6e13e5dccb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementCommonStockIssuedValue_ad783b5e-6569-40bb-b0a8-d4081483efa7" xlink:href="huma-20250930.xsd#huma_OptionAgreementCommonStockIssuedValue"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_OptionAgreementCommonStockIssuedValue_ad783b5e-6569-40bb-b0a8-d4081483efa7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue_cdb79a46-d59a-4237-aa90-71ace90c402a" xlink:href="huma-20250930.xsd#huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue"/>
    <link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_91b557ff-897a-4dd8-8138-37b4bb4c5526" xlink:to="loc_huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue_cdb79a46-d59a-4237-aa90-71ace90c402a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementScheduleofRevenueInterestLiabilityActivityDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#RevenueInterestPurchaseAgreementScheduleofRevenueInterestLiabilityActivityDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RevenueInterestPurchaseAgreementScheduleofRevenueInterestLiabilityActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_09efb514-6891-46cb-9003-f64462380b19" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestLiabilityTable_c03cf27f-0c3c-490e-97ae-b49f9e193f16" xlink:href="huma-20250930.xsd#huma_RevenueInterestLiabilityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_09efb514-6891-46cb-9003-f64462380b19" xlink:to="loc_huma_RevenueInterestLiabilityTable_c03cf27f-0c3c-490e-97ae-b49f9e193f16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_3593aa56-2895-449e-954b-88f9c264d6d7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_c03cf27f-0c3c-490e-97ae-b49f9e193f16" xlink:to="loc_us-gaap_DebtInstrumentAxis_3593aa56-2895-449e-954b-88f9c264d6d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_e5970513-bc07-4e9e-97bd-9e98aaa7aa7d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_3593aa56-2895-449e-954b-88f9c264d6d7" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_e5970513-bc07-4e9e-97bd-9e98aaa7aa7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestPurchaseAgreementMember_1fb0e1e7-480e-45de-8703-a2a7f5a00db1" xlink:href="huma-20250930.xsd#huma_RevenueInterestPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e5970513-bc07-4e9e-97bd-9e98aaa7aa7d" xlink:to="loc_huma_RevenueInterestPurchaseAgreementMember_1fb0e1e7-480e-45de-8703-a2a7f5a00db1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_d4d08516-b921-4601-92e7-e00f89127f2e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_c03cf27f-0c3c-490e-97ae-b49f9e193f16" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_d4d08516-b921-4601-92e7-e00f89127f2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_25b598c9-2852-4fba-bb50-b9596294f9a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d4d08516-b921-4601-92e7-e00f89127f2e" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_25b598c9-2852-4fba-bb50-b9596294f9a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_606f5d1b-fa89-4c9e-a0c2-83d3541d3108" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_25b598c9-2852-4fba-bb50-b9596294f9a2" xlink:to="loc_us-gaap_UnsecuredDebtMember_606f5d1b-fa89-4c9e-a0c2-83d3541d3108" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestLiabilityLineItems_c340b612-199c-4774-b005-896d0915bc04" xlink:href="huma-20250930.xsd#huma_RevenueInterestLiabilityLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityTable_c03cf27f-0c3c-490e-97ae-b49f9e193f16" xlink:to="loc_huma_RevenueInterestLiabilityLineItems_c340b612-199c-4774-b005-896d0915bc04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:href="huma-20250930.xsd#huma_RevenueInterestLiabilityActivityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityLineItems_c340b612-199c-4774-b005-896d0915bc04" xlink:to="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_2bfb1e62-8351-4382-a52b-160bc184f5c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_LongTermDebt_2bfb1e62-8351-4382-a52b-160bc184f5c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_de1cddae-492f-42a0-b3e4-fc46e608f9f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_InterestExpenseDebt_de1cddae-492f-42a0-b3e4-fc46e608f9f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_InterestExpenseDebtRevenueInterest_9261b3c1-11ea-4d95-992b-1a118aa77c8a" xlink:href="huma-20250930.xsd#huma_InterestExpenseDebtRevenueInterest"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_huma_InterestExpenseDebtRevenueInterest_9261b3c1-11ea-4d95-992b-1a118aa77c8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_0548f987-c0d1-4c23-84bd-0a2db91655dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_0548f987-c0d1-4c23-84bd-0a2db91655dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_4b077662-ff25-4ef6-9110-d36bb204f012" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_LongTermDebt_4b077662-ff25-4ef6-9110-d36bb204f012" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_419ee3a4-5a8d-42c1-8001-aba36236b344" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_LongTermDebtCurrent_419ee3a4-5a8d-42c1-8001-aba36236b344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_8039019b-0b24-4788-9014-f16221ca5ec5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RevenueInterestLiabilityActivityRollForward_9a265a83-7e8a-4053-8b54-4d949de527b9" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_8039019b-0b24-4788-9014-f16221ca5ec5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/LeasesNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#LeasesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/LeasesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_LesseeOperatingLeaseAnnualEscalations_e88d5fa2-fd85-47b6-a115-1264cd676a51" xlink:href="huma-20250930.xsd#huma_LesseeOperatingLeaseAnnualEscalations"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_huma_LesseeOperatingLeaseAnnualEscalations_e88d5fa2-fd85-47b6-a115-1264cd676a51" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_LesseeOperatingLeaseRentAbatementTerm_41f0e9b2-5662-47c0-9117-51baf87a63ba" xlink:href="huma-20250930.xsd#huma_LesseeOperatingLeaseRentAbatementTerm"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_huma_LesseeOperatingLeaseRentAbatementTerm_41f0e9b2-5662-47c0-9117-51baf87a63ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_IncreaseDecreaseInOperatingLeaseLiabilityFromLeaseModification_fd24447e-b6d8-4557-8d3a-3ac4ea0dadd4" xlink:href="huma-20250930.xsd#huma_IncreaseDecreaseInOperatingLeaseLiabilityFromLeaseModification"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_huma_IncreaseDecreaseInOperatingLeaseLiabilityFromLeaseModification_fd24447e-b6d8-4557-8d3a-3ac4ea0dadd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_IncreaseDecreaseInOperatingLeaseRightOfUseAssetFromLeaseModification_ba7b6778-214a-4c81-a4f1-45ca9a17bac1" xlink:href="huma-20250930.xsd#huma_IncreaseDecreaseInOperatingLeaseRightOfUseAssetFromLeaseModification"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_huma_IncreaseDecreaseInOperatingLeaseRightOfUseAssetFromLeaseModification_ba7b6778-214a-4c81-a4f1-45ca9a17bac1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_a5c9e8c8-a1fa-4553-b357-f9e1f16fde55" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiability"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_us-gaap_FinanceLeaseLiability_a5c9e8c8-a1fa-4553-b357-f9e1f16fde55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_21db0f91-d35b-4d55-8c17-caf49abd78aa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseRightOfUseAsset"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_21db0f91-d35b-4d55-8c17-caf49abd78aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_2545e720-4853-4c36-87e9-5a0bc2534b11" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_us-gaap_OperatingLeaseLiability_2545e720-4853-4c36-87e9-5a0bc2534b11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_29d8c769-67bc-47f3-b489-41f47601c970" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e2f9eb1e-6f90-48ec-940b-076d1e42d1df" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_29d8c769-67bc-47f3-b489-41f47601c970" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/LeasesTotalLeaseCostDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#LeasesTotalLeaseCostDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/LeasesTotalLeaseCostDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_a53b3b87-6be2-4042-a6a7-93f667f8f6fe" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeAndExpensesLesseeAbstract_e4d89e49-f07a-4855-9d42-3b1eb3e55177" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeAndExpensesLesseeAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_a53b3b87-6be2-4042-a6a7-93f667f8f6fe" xlink:to="loc_us-gaap_IncomeAndExpensesLesseeAbstract_e4d89e49-f07a-4855-9d42-3b1eb3e55177" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_e0072199-d132-4588-b9ce-b8b7c024176a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeAndExpensesLesseeAbstract_e4d89e49-f07a-4855-9d42-3b1eb3e55177" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_e0072199-d132-4588-b9ce-b8b7c024176a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseInterestExpense_44c43013-c806-4b0f-b765-b83a8e1a6182" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseInterestExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeAndExpensesLesseeAbstract_e4d89e49-f07a-4855-9d42-3b1eb3e55177" xlink:to="loc_us-gaap_FinanceLeaseInterestExpense_44c43013-c806-4b0f-b765-b83a8e1a6182" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FinanceLeaseCost_e5f3138b-e0b9-49b9-8d51-82eadfd604db" xlink:href="huma-20250930.xsd#huma_FinanceLeaseCost"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeAndExpensesLesseeAbstract_e4d89e49-f07a-4855-9d42-3b1eb3e55177" xlink:to="loc_huma_FinanceLeaseCost_e5f3138b-e0b9-49b9-8d51-82eadfd604db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_bdc3a9f9-3694-4363-9611-23a2047b555f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_a53b3b87-6be2-4042-a6a7-93f667f8f6fe" xlink:to="loc_us-gaap_OperatingLeaseCost_bdc3a9f9-3694-4363-9611-23a2047b555f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_e5246c3d-85db-4fe6-bee8-801bdf8af4a3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeaseCost"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_a53b3b87-6be2-4042-a6a7-93f667f8f6fe" xlink:to="loc_us-gaap_LeaseCost_e5246c3d-85db-4fe6-bee8-801bdf8af4a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/LeasesQuantitativeInformationAboutCompanysLeasesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#LeasesQuantitativeInformationAboutCompanysLeasesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/LeasesQuantitativeInformationAboutCompanysLeasesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_ff207c0a-a661-41d9-802a-597b00dc7fe4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashFlowOperatingActivitiesLesseeAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_ff207c0a-a661-41d9-802a-597b00dc7fe4" xlink:to="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseInterestPaymentOnLiability_f873e4fe-8785-481c-a54c-2cedbfa03e1b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseInterestPaymentOnLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:to="loc_us-gaap_FinanceLeaseInterestPaymentOnLiability_f873e4fe-8785-481c-a54c-2cedbfa03e1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_26ba483b-ddbf-4e11-975d-ee61300c9f71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_26ba483b-ddbf-4e11-975d-ee61300c9f71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_644edc83-6728-4e34-a815-39210ff795d6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:to="loc_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_644edc83-6728-4e34-a815-39210ff795d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_cc9019d7-da6e-41ea-9b13-a33472f7765e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowOperatingActivitiesLesseeAbstract_015af96c-487d-47b1-91be-aaf4514e7b01" xlink:to="loc_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_cc9019d7-da6e-41ea-9b13-a33472f7765e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowFinancingActivitiesLesseeAbstract_f98da58f-1f86-429f-88f3-ac831811907c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashFlowFinancingActivitiesLesseeAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_ff207c0a-a661-41d9-802a-597b00dc7fe4" xlink:to="loc_us-gaap_CashFlowFinancingActivitiesLesseeAbstract_f98da58f-1f86-429f-88f3-ac831811907c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_5fe364c3-ff24-4815-ab88-72c713bdef49" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeasePayments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowFinancingActivitiesLesseeAbstract_f98da58f-1f86-429f-88f3-ac831811907c" xlink:to="loc_us-gaap_OperatingLeasePayments_5fe364c3-ff24-4815-ab88-72c713bdef49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_bfe9f616-21f2-4f0b-85db-d2173375bbf0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowFinancingActivitiesLesseeAbstract_f98da58f-1f86-429f-88f3-ac831811907c" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_bfe9f616-21f2-4f0b-85db-d2173375bbf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_a613ad7d-5385-4406-b444-dc24c38d68cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowFinancingActivitiesLesseeAbstract_f98da58f-1f86-429f-88f3-ac831811907c" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_a613ad7d-5385-4406-b444-dc24c38d68cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#LeasesMaturitiesofLeaseLiabilitiesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_76288cff-5f3b-4144-b314-4929e91a3895" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_76288cff-5f3b-4144-b314-4929e91a3895" xlink:to="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_82f34437-6698-4d00-9aed-05c72ed431b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_82f34437-6698-4d00-9aed-05c72ed431b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_9a22e261-b930-41a4-9ec0-a8cff42da964" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_9a22e261-b930-41a4-9ec0-a8cff42da964" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FinanceLeaseLiabilityToBePaidYearTwoNetOfReimbursementForTenantImprovementCosts_bf929070-4102-4eb5-be6f-08dc97f33cb6" xlink:href="huma-20250930.xsd#huma_FinanceLeaseLiabilityToBePaidYearTwoNetOfReimbursementForTenantImprovementCosts"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_huma_FinanceLeaseLiabilityToBePaidYearTwoNetOfReimbursementForTenantImprovementCosts_bf929070-4102-4eb5-be6f-08dc97f33cb6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_b2da52f7-7448-453a-9f84-e34ecbd97c04" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_b2da52f7-7448-453a-9f84-e34ecbd97c04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_3557d2d2-8876-4823-9366-18b1fe289cc9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_3557d2d2-8876-4823-9366-18b1fe289cc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FinanceLeaseLiabilityToBePaidAfterYearFour_bbd25a84-7a67-4dac-91c7-e096fd13724e" xlink:href="huma-20250930.xsd#huma_FinanceLeaseLiabilityToBePaidAfterYearFour"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_huma_FinanceLeaseLiabilityToBePaidAfterYearFour_bbd25a84-7a67-4dac-91c7-e096fd13724e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_7ea1f7c4-b158-4ff0-9275-80ff166557db" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_7ea1f7c4-b158-4ff0-9275-80ff166557db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_c61b6980-c3d6-4d20-92dc-97cd1b5df5f5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_c61b6980-c3d6-4d20-92dc-97cd1b5df5f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_9856288b-b5f3-4934-b69a-c69faa55f673" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiability"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_78be130d-e4a4-46b2-954a-caa8272c34c0" xlink:to="loc_us-gaap_FinanceLeaseLiability_9856288b-b5f3-4934-b69a-c69faa55f673" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPublicOfferingsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsPublicOfferingsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPublicOfferingsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_317f6a9e-f3aa-4256-8f54-12d10ceba0ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_63195932-4e68-44d6-9530-c8f748af0c02" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_317f6a9e-f3aa-4256-8f54-12d10ceba0ce" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_63195932-4e68-44d6-9530-c8f748af0c02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_f40826b9-959d-495f-901f-7efd62396471" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_63195932-4e68-44d6-9530-c8f748af0c02" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_f40826b9-959d-495f-901f-7efd62396471" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_e5cf5cfa-4add-42d4-884d-9dcbd5006234" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_f40826b9-959d-495f-901f-7efd62396471" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_e5cf5cfa-4add-42d4-884d-9dcbd5006234" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PublicStockOfferingMember_90cb19ff-b197-4648-a1f7-8a0e69e69b42" xlink:href="huma-20250930.xsd#huma_PublicStockOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_e5cf5cfa-4add-42d4-884d-9dcbd5006234" xlink:to="loc_huma_PublicStockOfferingMember_90cb19ff-b197-4648-a1f7-8a0e69e69b42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OverAllotmentOptionMember_bb84e5bc-61f1-4b90-9b58-5bd8962c76ee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OverAllotmentOptionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_e5cf5cfa-4add-42d4-884d-9dcbd5006234" xlink:to="loc_us-gaap_OverAllotmentOptionMember_bb84e5bc-61f1-4b90-9b58-5bd8962c76ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_63195932-4e68-44d6-9530-c8f748af0c02" xlink:to="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_fae00a9f-9e7a-40bf-9d87-82bfaad6511f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_fae00a9f-9e7a-40bf-9d87-82bfaad6511f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_070a3029-8712-4c15-97ae-f716983940d3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_070a3029-8712-4c15-97ae-f716983940d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SaleOfStockOverAllotmentOptionPeriod_c1cc15a8-af9e-4fa9-89e7-d3ddfd2170d3" xlink:href="huma-20250930.xsd#huma_SaleOfStockOverAllotmentOptionPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:to="loc_huma_SaleOfStockOverAllotmentOptionPeriod_c1cc15a8-af9e-4fa9-89e7-d3ddfd2170d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_3841b7c3-d169-484a-88e8-d96ed1822045" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_a3db72d0-8ae3-44e7-b8f3-d69a68eb81f2" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_3841b7c3-d169-484a-88e8-d96ed1822045" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsEquityLineFinancingNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsEquityLineFinancingNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsEquityLineFinancingNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_abacaf6e-56b3-4695-8b42-71e1e5102dd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_abacaf6e-56b3-4695-8b42-71e1e5102dd1" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_22a0ab30-9def-435d-8d14-33134019fc07" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_22a0ab30-9def-435d-8d14-33134019fc07" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_c7e493b6-352c-4d71-8b28-2d33658b752a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_22a0ab30-9def-435d-8d14-33134019fc07" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_c7e493b6-352c-4d71-8b28-2d33658b752a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_36e16e65-bce8-4130-9e5d-3949b71a5087" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_c7e493b6-352c-4d71-8b28-2d33658b752a" xlink:to="loc_huma_EquityLineFinancingMember_36e16e65-bce8-4130-9e5d-3949b71a5087" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_7e7b9b64-bf97-4a73-8711-6a8b97202c71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_7e7b9b64-bf97-4a73-8711-6a8b97202c71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_8c9148b4-f722-4b40-bf35-77e9e0eb99df" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_7e7b9b64-bf97-4a73-8711-6a8b97202c71" xlink:to="loc_us-gaap_EquityComponentDomain_8c9148b4-f722-4b40-bf35-77e9e0eb99df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommitmentSharesMember_23fe23f4-4c48-444b-8181-f33c5d08a781" xlink:href="huma-20250930.xsd#huma_CommitmentSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_8c9148b4-f722-4b40-bf35-77e9e0eb99df" xlink:to="loc_huma_CommitmentSharesMember_23fe23f4-4c48-444b-8181-f33c5d08a781" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_cd4faf98-193a-4ea7-8bf0-6cd1498fdde5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_cd4faf98-193a-4ea7-8bf0-6cd1498fdde5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_b0fb5b1b-0ae0-4953-8d34-8ca6d717f43d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_cd4faf98-193a-4ea7-8bf0-6cd1498fdde5" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_b0fb5b1b-0ae0-4953-8d34-8ca6d717f43d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_f3c0646b-1e70-4aad-be68-4ee3783c91a3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_b0fb5b1b-0ae0-4953-8d34-8ca6d717f43d" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_f3c0646b-1e70-4aad-be68-4ee3783c91a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_c242c088-e22a-4015-8d08-d4658e460e1b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:to="loc_us-gaap_StatementClassOfStockAxis_c242c088-e22a-4015-8d08-d4658e460e1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_8883c721-964d-49a9-a58f-836de96169c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_c242c088-e22a-4015-8d08-d4658e460e1b" xlink:to="loc_us-gaap_ClassOfStockDomain_8883c721-964d-49a9-a58f-836de96169c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommitmentSharesMember_39a16fe8-95fa-41dc-a3f7-787158009bc2" xlink:href="huma-20250930.xsd#huma_CommitmentSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_8883c721-964d-49a9-a58f-836de96169c4" xlink:to="loc_huma_CommitmentSharesMember_39a16fe8-95fa-41dc-a3f7-787158009bc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_db4c2cf3-31dd-4cef-876b-7b2f2b5032a6" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_3615ba4f-cd4c-40d3-bab0-fea8507eabba" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountAuthorizedValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_3615ba4f-cd4c-40d3-bab0-fea8507eabba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementTerm_e974dc71-805a-4fe1-a2d6-a511283b8289" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementTerm"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_huma_CommonStockPurchaseAgreementTerm_e974dc71-805a-4fe1-a2d6-a511283b8289" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_75e73477-53fa-4de2-b3fc-709fe9643f72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_75e73477-53fa-4de2-b3fc-709fe9643f72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_9acb1950-7d8c-42f5-b919-f810b54f6426" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DerivativeAssets"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_us-gaap_DerivativeAssets_9acb1950-7d8c-42f5-b919-f810b54f6426" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharePrice_5622e6b5-74e6-4e6d-a978-b37f0ef5019b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_us-gaap_SharePrice_5622e6b5-74e6-4e6d-a978-b37f0ef5019b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_c3ea477e-9e17-4365-879b-8144d328a79e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_c3ea477e-9e17-4365-879b-8144d328a79e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountRemaining_b604acad-3ba3-4c3a-bfe4-7d4555456c9d" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountRemaining"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_fb8e06ef-e77a-4316-b797-8502fa188293" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountRemaining_b604acad-3ba3-4c3a-bfe4-7d4555456c9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_b48d694b-98f8-491d-a310-d43a00596883" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_b48d694b-98f8-491d-a310-d43a00596883" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_ba31c641-de73-4b08-93e2-27a5926478e1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_ba31c641-de73-4b08-93e2-27a5926478e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d1afe53d-d1c6-4216-8abb-414dfe4692b1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_ba31c641-de73-4b08-93e2-27a5926478e1" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d1afe53d-d1c6-4216-8abb-414dfe4692b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingMember_9e59d7e1-b700-4f6f-af69-e29da14be276" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d1afe53d-d1c6-4216-8abb-414dfe4692b1" xlink:to="loc_huma_October2024RegisteredDirectOfferingMember_9e59d7e1-b700-4f6f-af69-e29da14be276" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingMember_148dff05-0441-4a90-a5fa-69e0dade3d95" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d1afe53d-d1c6-4216-8abb-414dfe4692b1" xlink:to="loc_huma_November2024RegisteredDirectOfferingMember_148dff05-0441-4a90-a5fa-69e0dade3d95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingMember_f8ada311-4c66-45ef-a9b8-d5e7b9c3ada9" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d1afe53d-d1c6-4216-8abb-414dfe4692b1" xlink:to="loc_huma_October2025RegisteredDirectOfferingMember_f8ada311-4c66-45ef-a9b8-d5e7b9c3ada9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_b36bceb1-fe64-49ad-801c-219283712df5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_b36bceb1-fe64-49ad-801c-219283712df5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_fd9cfe3f-99c3-421f-93c1-a343ba0cc462" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_b36bceb1-fe64-49ad-801c-219283712df5" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_fd9cfe3f-99c3-421f-93c1-a343ba0cc462" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_627d5986-b8bb-4f6a-819d-4fa2b5e2a32a" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_fd9cfe3f-99c3-421f-93c1-a343ba0cc462" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_627d5986-b8bb-4f6a-819d-4fa2b5e2a32a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_2cc35b04-873c-4179-9702-d60e4797d856" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_fd9cfe3f-99c3-421f-93c1-a343ba0cc462" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_2cc35b04-873c-4179-9702-d60e4797d856" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_d1c3b7c7-7556-48e6-9937-b8a14d1c8082" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_fd9cfe3f-99c3-421f-93c1-a343ba0cc462" xlink:to="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_d1c3b7c7-7556-48e6-9937-b8a14d1c8082" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_4496d7c4-4ac1-4d92-aef1-1ca65a703f9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_4496d7c4-4ac1-4d92-aef1-1ca65a703f9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_12e14a50-941c-45e5-b494-121b1e89174a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_4496d7c4-4ac1-4d92-aef1-1ca65a703f9c" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_12e14a50-941c-45e5-b494-121b1e89174a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_f53b6818-4d83-4f6e-b1ff-a0b63b223e9d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_12e14a50-941c-45e5-b494-121b1e89174a" xlink:to="loc_us-gaap_SubsequentEventMember_f53b6818-4d83-4f6e-b1ff-a0b63b223e9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_f0c99fc0-f37e-4e6e-989b-f3182be7f174" xlink:to="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_d70012fe-5b75-492f-b2c2-701701756c16" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_d70012fe-5b75-492f-b2c2-701701756c16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_acf68783-6163-4ca4-a595-7ea41e16267a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_acf68783-6163-4ca4-a595-7ea41e16267a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_fcd89c8e-0812-4158-a740-c456bc41188e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_fcd89c8e-0812-4158-a740-c456bc41188e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_69853517-b869-4eb2-8268-659353dab57e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_69853517-b869-4eb2-8268-659353dab57e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_ef9aaf16-356d-429e-9f45-94ba1e867e10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_c99f67c5-6c93-44df-a62a-88108ef5c3b0" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_ef9aaf16-356d-429e-9f45-94ba1e867e10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsATMFacilityNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsATMFacilityNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsATMFacilityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_8ca8d1f7-67e5-4eea-b1c3-9f1387a7c6cf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_b558806d-b09d-4356-bf50-8056d1015b52" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_8ca8d1f7-67e5-4eea-b1c3-9f1387a7c6cf" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_b558806d-b09d-4356-bf50-8056d1015b52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_067eba9c-6f95-48e5-a8f5-b031350270fd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_b558806d-b09d-4356-bf50-8056d1015b52" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_067eba9c-6f95-48e5-a8f5-b031350270fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_df958d60-19ce-4e4d-bde8-ec8ce5dcc546" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_067eba9c-6f95-48e5-a8f5-b031350270fd" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_df958d60-19ce-4e4d-bde8-ec8ce5dcc546" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ATMFacilityMember_9343a352-3b60-464b-a9cd-06cdc9f27b57" xlink:href="huma-20250930.xsd#huma_ATMFacilityMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_df958d60-19ce-4e4d-bde8-ec8ce5dcc546" xlink:to="loc_huma_ATMFacilityMember_9343a352-3b60-464b-a9cd-06cdc9f27b57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_b558806d-b09d-4356-bf50-8056d1015b52" xlink:to="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_0d445a44-3f56-478d-ba1c-82e4858fbab2" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountAuthorizedValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountAuthorizedValue_0d445a44-3f56-478d-ba1c-82e4858fbab2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_0974fb3f-d373-4b12-8ec4-a2040299e672" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_0974fb3f-d373-4b12-8ec4-a2040299e672" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SaleOfStockAveragePricePerShare_7e52c673-cae5-47aa-a9d8-28a09a25fcab" xlink:href="huma-20250930.xsd#huma_SaleOfStockAveragePricePerShare"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:to="loc_huma_SaleOfStockAveragePricePerShare_7e52c673-cae5-47aa-a9d8-28a09a25fcab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_339db55d-ab23-41d8-a56e-8c9c0cabb1d3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_339db55d-ab23-41d8-a56e-8c9c0cabb1d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockPurchaseAgreementAmountRemaining_27e9a513-b8d2-4732-8e5a-c811bbb1fb88" xlink:href="huma-20250930.xsd#huma_CommonStockPurchaseAgreementAmountRemaining"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7ff80614-4a7e-4e7e-82cc-a4ec79db98c8" xlink:to="loc_huma_CommonStockPurchaseAgreementAmountRemaining_27e9a513-b8d2-4732-8e5a-c811bbb1fb88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsCommonStockNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsCommonStockNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsCommonStockNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_675e1ef8-9484-4709-97da-6bed3c6f991c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_986638d4-014a-43b0-96ee-5a6d75d72b40" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_675e1ef8-9484-4709-97da-6bed3c6f991c" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_986638d4-014a-43b0-96ee-5a6d75d72b40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStock_d968f8a8-a9ff-4198-b2f8-9849927b399a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DividendsCommonStock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_675e1ef8-9484-4709-97da-6bed3c6f991c" xlink:to="loc_us-gaap_DividendsCommonStock_d968f8a8-a9ff-4198-b2f8-9849927b399a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockNumberOfVotesPerUnitOfSharesHeld_38a62f03-f584-4c35-b5fd-ccda60c6b274" xlink:href="huma-20250930.xsd#huma_CommonStockNumberOfVotesPerUnitOfSharesHeld"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_675e1ef8-9484-4709-97da-6bed3c6f991c" xlink:to="loc_huma_CommonStockNumberOfVotesPerUnitOfSharesHeld_38a62f03-f584-4c35-b5fd-ccda60c6b274" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsCommonStockforFutureIssuancesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsCommonStockforFutureIssuancesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsCommonStockforFutureIssuancesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_9b6e89cd-f4dd-410a-9a56-0bd18a0dbed3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_9b6e89cd-f4dd-410a-9a56-0bd18a0dbed3" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CapitalSharesReservedForFutureIssuanceAxis_60b78ad1-89cc-42a8-bc62-06f5e562e0c0" xlink:href="huma-20250930.xsd#huma_CapitalSharesReservedForFutureIssuanceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:to="loc_huma_CapitalSharesReservedForFutureIssuanceAxis_60b78ad1-89cc-42a8-bc62-06f5e562e0c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:href="huma-20250930.xsd#huma_CapitalSharesReservedForFutureIssuanceDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceAxis_60b78ad1-89cc-42a8-bc62-06f5e562e0c0" xlink:to="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockReservedForContingentConsiderationSharesMember_da44d1f3-ce14-47c1-9b32-a3d592055f51" xlink:href="huma-20250930.xsd#huma_CommonStockReservedForContingentConsiderationSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_huma_CommonStockReservedForContingentConsiderationSharesMember_da44d1f3-ce14-47c1-9b32-a3d592055f51" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EquityLineFinancingMember_cedaf1ad-17fa-494c-9de8-76d404efe6ef" xlink:href="huma-20250930.xsd#huma_EquityLineFinancingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_huma_EquityLineFinancingMember_cedaf1ad-17fa-494c-9de8-76d404efe6ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockReservedForATMFacilityMember_2b38e7e1-5492-4f9a-b071-07f2e6f467c2" xlink:href="huma-20250930.xsd#huma_CommonStockReservedForATMFacilityMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_huma_CommonStockReservedForATMFacilityMember_2b38e7e1-5492-4f9a-b071-07f2e6f467c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommonStockReservedForOptionAgreementMember_e57f6de9-70eb-4a1a-831f-c1d5a435b2ae" xlink:href="huma-20250930.xsd#huma_CommonStockReservedForOptionAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_huma_CommonStockReservedForOptionAgreementMember_e57f6de9-70eb-4a1a-831f-c1d5a435b2ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_c926988e-8971-4f24-9bf9-03008a51d594" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_us-gaap_EmployeeStockOptionMember_c926988e-8971-4f24-9bf9-03008a51d594" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionsAvailableForIssuanceUnderStockPlansMember_7ce633e6-7801-4276-8ad0-ec5058e91d2a" xlink:href="huma-20250930.xsd#huma_OptionsAvailableForIssuanceUnderStockPlansMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_huma_OptionsAvailableForIssuanceUnderStockPlansMember_7ce633e6-7801-4276-8ad0-ec5058e91d2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_b3bb55a2-d65a-4c65-a2d8-2a82a4b88ac4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CapitalSharesReservedForFutureIssuanceDomain_565584c8-e80b-4248-987a-315849b029f4" xlink:to="loc_us-gaap_WarrantMember_b3bb55a2-d65a-4c65-a2d8-2a82a4b88ac4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_8387f8e5-b84e-45a5-8e23-313ec9411a82" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:to="loc_srt_CounterpartyNameAxis_8387f8e5-b84e-45a5-8e23-313ec9411a82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8bcd8117-29f4-40c5-afc4-3f84bd1c93e7" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_8387f8e5-b84e-45a5-8e23-313ec9411a82" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8bcd8117-29f4-40c5-afc4-3f84bd1c93e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_c1acf73b-ba2a-43bb-a277-6de503e35354" xlink:href="huma-20250930.xsd#huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8bcd8117-29f4-40c5-afc4-3f84bd1c93e7" xlink:to="loc_huma_TPCInvestmentsIIILPAndTPCInvestmentSolutionsLPMember_c1acf73b-ba2a-43bb-a277-6de503e35354" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_65313af2-967d-448f-a6dd-85ccaf2f84fc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:to="loc_us-gaap_DebtInstrumentAxis_65313af2-967d-448f-a6dd-85ccaf2f84fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_b497f12b-8a40-4f0b-acd5-17588b3dc0bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_65313af2-967d-448f-a6dd-85ccaf2f84fc" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_b497f12b-8a40-4f0b-acd5-17588b3dc0bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionPurchaseAgreementMember_be45d119-55e3-48c5-b003-cf5d5bcbdf23" xlink:href="huma-20250930.xsd#huma_OptionPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_b497f12b-8a40-4f0b-acd5-17588b3dc0bf" xlink:to="loc_huma_OptionPurchaseAgreementMember_be45d119-55e3-48c5-b003-cf5d5bcbdf23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_0d5ca677-36d6-42ea-ad6e-9061546a8987" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_5aa11e7c-d64b-49f8-b5b3-d79cd375bf3f" xlink:to="loc_us-gaap_ClassOfStockLineItems_0d5ca677-36d6-42ea-ad6e-9061546a8987" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_d1d4e2f4-9f41-4b7b-b220-e124f5bb6d5b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0d5ca677-36d6-42ea-ad6e-9061546a8987" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_d1d4e2f4-9f41-4b7b-b220-e124f5bb6d5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue_c26d5b1f-de49-4ee2-b8a5-934cada1e8be" xlink:href="huma-20250930.xsd#huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0d5ca677-36d6-42ea-ad6e-9061546a8987" xlink:to="loc_huma_OptionAgreementRemainingSharesAuthorizedForIssuanceValue_c26d5b1f-de49-4ee2-b8a5-934cada1e8be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OptionAgreementExercisePrice_a8f34c81-e8a0-4e5a-8aed-ab349288810a" xlink:href="huma-20250930.xsd#huma_OptionAgreementExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0d5ca677-36d6-42ea-ad6e-9061546a8987" xlink:to="loc_huma_OptionAgreementExercisePrice_a8f34c81-e8a0-4e5a-8aed-ab349288810a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPreferredStockNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsPreferredStockNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPreferredStockNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_a795f5a6-c0ee-4297-bcbe-9593642562e2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_d736bea9-e1e9-4781-a0a8-0009aea36e0d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_a795f5a6-c0ee-4297-bcbe-9593642562e2" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_d736bea9-e1e9-4781-a0a8-0009aea36e0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_63db5914-cf2b-432b-978f-138b1dfccb25" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_a795f5a6-c0ee-4297-bcbe-9593642562e2" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_63db5914-cf2b-432b-978f-138b1dfccb25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_cf63554d-6192-408c-9464-b8066994d81d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_a795f5a6-c0ee-4297-bcbe-9593642562e2" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_cf63554d-6192-408c-9464-b8066994d81d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsWarrantsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_33ad3dd4-7d13-4e29-86bb-e5ae3d53dcdf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_c9c1b642-7bcc-446e-98b3-ee89f25892d0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_33ad3dd4-7d13-4e29-86bb-e5ae3d53dcdf" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_c9c1b642-7bcc-446e-98b3-ee89f25892d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis_702bffef-b2be-4cae-9158-03ca8d84cdb0" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LegalEntityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_c9c1b642-7bcc-446e-98b3-ee89f25892d0" xlink:to="loc_dei_LegalEntityAxis_702bffef-b2be-4cae-9158-03ca8d84cdb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityDomain_4e57404d-bd07-403a-8e1b-09adddb70fef" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_702bffef-b2be-4cae-9158-03ca8d84cdb0" xlink:to="loc_dei_EntityDomain_4e57404d-bd07-403a-8e1b-09adddb70fef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_HumacyteIncMember_07b06d29-f4d9-4b5c-9736-81f4d3d3684f" xlink:href="huma-20250930.xsd#huma_HumacyteIncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_4e57404d-bd07-403a-8e1b-09adddb70fef" xlink:to="loc_huma_HumacyteIncMember_07b06d29-f4d9-4b5c-9736-81f4d3d3684f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_2fb3a610-2559-45f1-a5fc-fb17b3dbf9eb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_c9c1b642-7bcc-446e-98b3-ee89f25892d0" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_2fb3a610-2559-45f1-a5fc-fb17b3dbf9eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_2fb3a610-2559-45f1-a5fc-fb17b3dbf9eb" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PrivatePlacementWarrantsMember_ef8906ba-8524-40bc-96fa-25403f9f407a" xlink:href="huma-20250930.xsd#huma_PrivatePlacementWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:to="loc_huma_PrivatePlacementWarrantsMember_ef8906ba-8524-40bc-96fa-25403f9f407a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PublicWarrantsMember_a0eba940-aaad-440e-a632-655bae8ddba5" xlink:href="huma-20250930.xsd#huma_PublicWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:to="loc_huma_PublicWarrantsMember_a0eba940-aaad-440e-a632-655bae8ddba5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_13ff16d2-9f54-42ab-a796-1113cf2886ea" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_13ff16d2-9f54-42ab-a796-1113cf2886ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_1a0a282b-8640-4c96-828d-54c9444273be" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_f11a727b-95ed-4a5e-806f-5df0aa19a80a" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_1a0a282b-8640-4c96-828d-54c9444273be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_37f9a5e0-e047-41c6-886c-4dd3b591cffb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_c9c1b642-7bcc-446e-98b3-ee89f25892d0" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_37f9a5e0-e047-41c6-886c-4dd3b591cffb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_11e3b82b-fce5-4156-8343-0f735e092321" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_37f9a5e0-e047-41c6-886c-4dd3b591cffb" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_11e3b82b-fce5-4156-8343-0f735e092321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsWarrantsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsWarrantsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsWarrantsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_bd9a745f-264f-4bfb-bf93-e9f96b8f0ffd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_bd9a745f-264f-4bfb-bf93-e9f96b8f0ffd" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_f4bf6207-b635-41ff-a41f-98f60eabc5a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_StatementClassOfStockAxis_f4bf6207-b635-41ff-a41f-98f60eabc5a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_e3fd88cd-2005-4880-950b-3d43985a2081" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_f4bf6207-b635-41ff-a41f-98f60eabc5a2" xlink:to="loc_us-gaap_ClassOfStockDomain_e3fd88cd-2005-4880-950b-3d43985a2081" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_eb898dee-7c0d-4d24-8343-cbceeb184bc4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_e3fd88cd-2005-4880-950b-3d43985a2081" xlink:to="loc_us-gaap_WarrantMember_eb898dee-7c0d-4d24-8343-cbceeb184bc4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_4cd23b93-0064-4682-80ac-e18f732722b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_4cd23b93-0064-4682-80ac-e18f732722b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_4cd23b93-0064-4682-80ac-e18f732722b0" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_db3248a6-905c-4876-bb7f-ceb741a50578" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_db3248a6-905c-4876-bb7f-ceb741a50578" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_e596dc29-b96f-4dab-ad77-59bebd11ad90" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_e596dc29-b96f-4dab-ad77-59bebd11ad90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_a8419821-09b4-4abe-9d9a-f9534f38275d" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:to="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_a8419821-09b4-4abe-9d9a-f9534f38275d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_57e5d4c8-8501-465a-b169-22a3519f0665" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_d55076a7-2a06-418a-92bb-3cefabc24fed" xlink:to="loc_us-gaap_WarrantMember_57e5d4c8-8501-465a-b169-22a3519f0665" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_f98d2ea1-8a3d-46b6-b37e-6bc1fbd766fa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_DebtInstrumentAxis_f98d2ea1-8a3d-46b6-b37e-6bc1fbd766fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_1780e199-819e-4fe2-b619-a27e188ac93b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_f98d2ea1-8a3d-46b6-b37e-6bc1fbd766fa" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_1780e199-819e-4fe2-b619-a27e188ac93b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TermLoanAgreementMember_0b4d5617-d04b-444e-94f5-8c88bef003d5" xlink:href="huma-20250930.xsd#huma_TermLoanAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1780e199-819e-4fe2-b619-a27e188ac93b" xlink:to="loc_huma_TermLoanAgreementMember_0b4d5617-d04b-444e-94f5-8c88bef003d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_dccee640-ae63-4bfe-bbed-8ce1948ed3bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_dccee640-ae63-4bfe-bbed-8ce1948ed3bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_2f28724c-4d64-45a3-9c7d-3bac1adcebe8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_dccee640-ae63-4bfe-bbed-8ce1948ed3bf" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_2f28724c-4d64-45a3-9c7d-3bac1adcebe8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_86a23550-7ec5-4635-bfe2-0171c9290f7d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_2f28724c-4d64-45a3-9c7d-3bac1adcebe8" xlink:to="loc_us-gaap_SubsequentEventMember_86a23550-7ec5-4635-bfe2-0171c9290f7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_afb59adc-c79a-4328-96bf-6282002d2187" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_afb59adc-c79a-4328-96bf-6282002d2187" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f83ad575-cd7e-45e0-92b1-926afca505d1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_afb59adc-c79a-4328-96bf-6282002d2187" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f83ad575-cd7e-45e0-92b1-926afca505d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingMember_bee67fe0-d953-499f-a302-40c50b08b111" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f83ad575-cd7e-45e0-92b1-926afca505d1" xlink:to="loc_huma_October2025RegisteredDirectOfferingMember_bee67fe0-d953-499f-a302-40c50b08b111" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_8ce10023-bac5-44d2-8415-805474afb787" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ClassOfWarrantOrRightExpired_18595fa1-fd4b-47d0-b770-235c0bbda962" xlink:href="huma-20250930.xsd#huma_ClassOfWarrantOrRightExpired"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:to="loc_huma_ClassOfWarrantOrRightExpired_18595fa1-fd4b-47d0-b770-235c0bbda962" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_10fc1175-29e9-448c-8cd2-ae6c52baee45" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_10fc1175-29e9-448c-8cd2-ae6c52baee45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_3d8a4a75-ae0d-452b-9a4b-ee8deb34c17e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_3d8a4a75-ae0d-452b-9a4b-ee8deb34c17e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_a93eaf98-6d17-4df7-a765-2b55fe9d58a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_ad8bb781-b229-4be5-b802-8344d3e21b48" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_a93eaf98-6d17-4df7-a765-2b55fe9d58a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPublicandPrivatePlacementWarrantsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsPublicandPrivatePlacementWarrantsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPublicandPrivatePlacementWarrantsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_22906867-adc3-4298-8dcf-6feffb491a8c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_22906867-adc3-4298-8dcf-6feffb491a8c" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_5f58e6cf-79a5-41ae-a3a5-5367612bda04" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_5f58e6cf-79a5-41ae-a3a5-5367612bda04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ad93c697-dc4c-4921-8d68-69c0edf94143" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_5f58e6cf-79a5-41ae-a3a5-5367612bda04" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ad93c697-dc4c-4921-8d68-69c0edf94143" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MergerAgreementMember_1ae1213f-759f-4aee-8be8-daa206986c89" xlink:href="huma-20250930.xsd#huma_MergerAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ad93c697-dc4c-4921-8d68-69c0edf94143" xlink:to="loc_huma_MergerAgreementMember_1ae1213f-759f-4aee-8be8-daa206986c89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_2e0db106-3288-4c7e-93bb-22c7ff80b467" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_2e0db106-3288-4c7e-93bb-22c7ff80b467" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_44fe9251-1c08-432e-b0ed-ccd067f2114a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_2e0db106-3288-4c7e-93bb-22c7ff80b467" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_44fe9251-1c08-432e-b0ed-ccd067f2114a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PublicWarrantsMember_db77eec7-c83e-444f-b6cc-ddb5e29266a0" xlink:href="huma-20250930.xsd#huma_PublicWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_44fe9251-1c08-432e-b0ed-ccd067f2114a" xlink:to="loc_huma_PublicWarrantsMember_db77eec7-c83e-444f-b6cc-ddb5e29266a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PrivatePlacementWarrantsMember_35bb5657-0139-4d60-bfa3-d271420051a3" xlink:href="huma-20250930.xsd#huma_PrivatePlacementWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_44fe9251-1c08-432e-b0ed-ccd067f2114a" xlink:to="loc_huma_PrivatePlacementWarrantsMember_35bb5657-0139-4d60-bfa3-d271420051a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_bb211f4e-ae9d-4e9b-a116-5e9a14b3c66b" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_44fe9251-1c08-432e-b0ed-ccd067f2114a" xlink:to="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_bb211f4e-ae9d-4e9b-a116-5e9a14b3c66b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_2d85e33f-c9f3-44ae-a93b-e8f106a41fc4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_StatementClassOfStockAxis_2d85e33f-c9f3-44ae-a93b-e8f106a41fc4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_2f5be1de-68c6-4ebe-9ba7-7bc947a49d83" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_2d85e33f-c9f3-44ae-a93b-e8f106a41fc4" xlink:to="loc_us-gaap_ClassOfStockDomain_2f5be1de-68c6-4ebe-9ba7-7bc947a49d83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_ccebb463-9ae1-41e2-93c7-f2528cc90db9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_2f5be1de-68c6-4ebe-9ba7-7bc947a49d83" xlink:to="loc_us-gaap_WarrantMember_ccebb463-9ae1-41e2-93c7-f2528cc90db9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_d65238b0-def5-4945-bb58-182ac0b97525" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_d65238b0-def5-4945-bb58-182ac0b97525" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a97078a0-09ec-4f15-88fb-c5079d9a3a9d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_d65238b0-def5-4945-bb58-182ac0b97525" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a97078a0-09ec-4f15-88fb-c5079d9a3a9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_AssumptionOfPubliclyTradedSecuritiesMember_1c936a59-c9a0-49e0-bcaa-e299a9df8a94" xlink:href="huma-20250930.xsd#huma_AssumptionOfPubliclyTradedSecuritiesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a97078a0-09ec-4f15-88fb-c5079d9a3a9d" xlink:to="loc_huma_AssumptionOfPubliclyTradedSecuritiesMember_1c936a59-c9a0-49e0-bcaa-e299a9df8a94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrivatePlacementMember_1c03652d-5924-4e87-b270-9766e0f0a9fa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrivatePlacementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a97078a0-09ec-4f15-88fb-c5079d9a3a9d" xlink:to="loc_us-gaap_PrivatePlacementMember_1c03652d-5924-4e87-b270-9766e0f0a9fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingMember_185d0d2a-9eb5-4f76-a64b-be4938390202" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_a97078a0-09ec-4f15-88fb-c5079d9a3a9d" xlink:to="loc_huma_October2025RegisteredDirectOfferingMember_185d0d2a-9eb5-4f76-a64b-be4938390202" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_f4633962-8476-4a76-a1bf-d91b5886cbe2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_f4633962-8476-4a76-a1bf-d91b5886cbe2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_ec78c7b3-7381-49ab-a6e4-fc4fea01db03" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_f4633962-8476-4a76-a1bf-d91b5886cbe2" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_ec78c7b3-7381-49ab-a6e4-fc4fea01db03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputSharePriceMember_386c2cd2-677a-493e-8ab1-0e0b1b1913f9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputSharePriceMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_ec78c7b3-7381-49ab-a6e4-fc4fea01db03" xlink:to="loc_us-gaap_MeasurementInputSharePriceMember_386c2cd2-677a-493e-8ab1-0e0b1b1913f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_08e3457b-71d5-45f2-81ad-0ebf98152dc4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_08e3457b-71d5-45f2-81ad-0ebf98152dc4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_24cc9b15-6ceb-4564-8491-2cae5fb60c95" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_08e3457b-71d5-45f2-81ad-0ebf98152dc4" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_24cc9b15-6ceb-4564-8491-2cae5fb60c95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_de17e654-99c9-4799-8359-553a961b0df7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_24cc9b15-6ceb-4564-8491-2cae5fb60c95" xlink:to="loc_us-gaap_SubsequentEventMember_de17e654-99c9-4799-8359-553a961b0df7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7e11e21b-1008-41bb-ba24-1ba5cd2f78bf" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_3bdec742-b0b2-458e-89bc-767c18455fed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_3bdec742-b0b2-458e-89bc-767c18455fed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight_292650a7-5709-43a1-953e-125a64b1d3a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight_292650a7-5709-43a1-953e-125a64b1d3a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_1496fab8-1aca-4138-b24f-4f4e1aaadef6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_1496fab8-1aca-4138-b24f-4f4e1aaadef6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_d139df72-a49d-4b62-a0a7-8ccbf5254c71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_d139df72-a49d-4b62-a0a7-8ccbf5254c71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ClassOfWarrantOrRightRedemptionThreshold_a27519fb-0190-4e44-86c0-f25110cf8c72" xlink:href="huma-20250930.xsd#huma_ClassOfWarrantOrRightRedemptionThreshold"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_huma_ClassOfWarrantOrRightRedemptionThreshold_a27519fb-0190-4e44-86c0-f25110cf8c72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_d3d9b42a-e9cc-4cf5-ae69-3382a205a95e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingMeasurementInput"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_d3d9b42a-e9cc-4cf5-ae69-3382a205a95e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_0a72c952-ced5-4d46-b001-1736bb95d505" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_0a72c952-ced5-4d46-b001-1736bb95d505" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAdjustmentOfWarrants_9b6cdd6d-322d-48f4-aabb-5bfbf9873bfc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAdjustmentOfWarrants"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_FairValueAdjustmentOfWarrants_9b6cdd6d-322d-48f4-aabb-5bfbf9873bfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_391618a2-2a3b-46b7-ac7f-bcdd3dd255de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_bd8024a2-1bf5-4f96-b739-ba30039f418d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_391618a2-2a3b-46b7-ac7f-bcdd3dd255de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPrivatePlacementWarrantsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsPrivatePlacementWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsPrivatePlacementWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_05a41ad0-a217-4309-af3e-e2ff17a7313e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_7b3d3ca2-6601-45a6-a9df-d344d1786983" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_05a41ad0-a217-4309-af3e-e2ff17a7313e" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_7b3d3ca2-6601-45a6-a9df-d344d1786983" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_d5aaa34d-e84c-4e92-b689-3feb89635295" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7b3d3ca2-6601-45a6-a9df-d344d1786983" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_d5aaa34d-e84c-4e92-b689-3feb89635295" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_c9a85940-99e9-436b-a037-04d0ae8a82a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_d5aaa34d-e84c-4e92-b689-3feb89635295" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_c9a85940-99e9-436b-a037-04d0ae8a82a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PrivatePlacementWarrantsMember_40bb4a1b-8159-4d09-8c2a-bd062ea008ce" xlink:href="huma-20250930.xsd#huma_PrivatePlacementWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_c9a85940-99e9-436b-a037-04d0ae8a82a1" xlink:to="loc_huma_PrivatePlacementWarrantsMember_40bb4a1b-8159-4d09-8c2a-bd062ea008ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_9ba8908a-8fe5-4e51-9b60-0656fc85edc5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7b3d3ca2-6601-45a6-a9df-d344d1786983" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_9ba8908a-8fe5-4e51-9b60-0656fc85edc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_9ba8908a-8fe5-4e51-9b60-0656fc85edc5" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputSharePriceMember_b97f77ab-66f9-4cd2-8ef0-781f3f31450e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputSharePriceMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputSharePriceMember_b97f77ab-66f9-4cd2-8ef0-781f3f31450e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExercisePriceMember_57c4843a-c8d9-4111-bf29-b9dedef3a548" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExercisePriceMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputExercisePriceMember_57c4843a-c8d9-4111-bf29-b9dedef3a548" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_1c9cda4e-3bf3-47c6-b7d1-6a094a27d931" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_1c9cda4e-3bf3-47c6-b7d1-6a094a27d931" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_2d4cd715-b3ab-455b-8374-cbf565864d67" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputPriceVolatilityMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_2d4cd715-b3ab-455b-8374-cbf565864d67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_5a23232f-26bb-4807-916c-d4a9a5bc5b97" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_5a23232f-26bb-4807-916c-d4a9a5bc5b97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedDividendRateMember_7da3eaf3-3ed8-4447-ae50-a44002b2597a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedDividendRateMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_8d94966b-1e6e-47b8-9a9c-17d1b0572daf" xlink:to="loc_us-gaap_MeasurementInputExpectedDividendRateMember_7da3eaf3-3ed8-4447-ae50-a44002b2597a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_e26f7d73-aa7b-4c43-92e4-35333e9be5dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_7b3d3ca2-6601-45a6-a9df-d344d1786983" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_e26f7d73-aa7b-4c43-92e4-35333e9be5dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_17512be7-2f1f-4ae7-b930-b645e7ac0a66" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingMeasurementInput"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_e26f7d73-aa7b-4c43-92e4-35333e9be5dd" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_17512be7-2f1f-4ae7-b930-b645e7ac0a66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_43b04f85-aa61-4818-9c71-161fe2688800" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_43b04f85-aa61-4818-9c71-161fe2688800" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_7edb7bd0-fa23-4f7a-ae10-3bca39bc3fe1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_7edb7bd0-fa23-4f7a-ae10-3bca39bc3fe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_88b795a1-fe8d-45be-8214-dd522d7eb374" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_7edb7bd0-fa23-4f7a-ae10-3bca39bc3fe1" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_88b795a1-fe8d-45be-8214-dd522d7eb374" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_640d0798-0a33-4a15-970b-8abbc98300df" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_88b795a1-fe8d-45be-8214-dd522d7eb374" xlink:to="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_640d0798-0a33-4a15-970b-8abbc98300df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants180DayOctober2024Member_62394f6c-faa3-4210-a2b2-699f4a81b65b" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants180DayOctober2024Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_640d0798-0a33-4a15-970b-8abbc98300df" xlink:to="loc_huma_RegisteredDirectWarrants180DayOctober2024Member_62394f6c-faa3-4210-a2b2-699f4a81b65b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants1640DayOctober2024Member_a1bcc92c-78de-42d9-becb-58cf8b11b9a8" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants1640DayOctober2024Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_October2024RegisteredDirectOfferingWarrantsMember_640d0798-0a33-4a15-970b-8abbc98300df" xlink:to="loc_huma_RegisteredDirectWarrants1640DayOctober2024Member_a1bcc92c-78de-42d9-becb-58cf8b11b9a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_a7748692-e213-453e-83e6-7a0d706d642f" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_88b795a1-fe8d-45be-8214-dd522d7eb374" xlink:to="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_a7748692-e213-453e-83e6-7a0d706d642f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants180DayNovember2024Member_d94d160e-3649-46cb-b5f7-539ecbc8f707" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants180DayNovember2024Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_a7748692-e213-453e-83e6-7a0d706d642f" xlink:to="loc_huma_RegisteredDirectWarrants180DayNovember2024Member_d94d160e-3649-46cb-b5f7-539ecbc8f707" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants1640DayNovember2024Member_25b5317b-ae88-46fe-818f-b1ca4dea2a7c" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants1640DayNovember2024Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_November2024RegisteredDirectOfferingWarrantsMember_a7748692-e213-453e-83e6-7a0d706d642f" xlink:to="loc_huma_RegisteredDirectWarrants1640DayNovember2024Member_25b5317b-ae88-46fe-818f-b1ca4dea2a7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_ccb4f875-48fb-408d-8eaf-234dce2d46e8" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_88b795a1-fe8d-45be-8214-dd522d7eb374" xlink:to="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_ccb4f875-48fb-408d-8eaf-234dce2d46e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_a55fee8a-2f6c-416b-8ec2-c6947ab78794" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_a55fee8a-2f6c-416b-8ec2-c6947ab78794" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_cff40419-f396-4730-9163-2e00f2211801" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_a55fee8a-2f6c-416b-8ec2-c6947ab78794" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_cff40419-f396-4730-9163-2e00f2211801" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectOfferingsMember_979a1170-5835-45ba-b60e-d80028966062" xlink:href="huma-20250930.xsd#huma_RegisteredDirectOfferingsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_cff40419-f396-4730-9163-2e00f2211801" xlink:to="loc_huma_RegisteredDirectOfferingsMember_979a1170-5835-45ba-b60e-d80028966062" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2024RegisteredDirectOfferingMember_70c3c3e9-b1f5-4a7c-94e6-495d96486da5" xlink:href="huma-20250930.xsd#huma_October2024RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RegisteredDirectOfferingsMember_979a1170-5835-45ba-b60e-d80028966062" xlink:to="loc_huma_October2024RegisteredDirectOfferingMember_70c3c3e9-b1f5-4a7c-94e6-495d96486da5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_November2024RegisteredDirectOfferingMember_7686e641-cb23-43e7-9e98-f050ecd63631" xlink:href="huma-20250930.xsd#huma_November2024RegisteredDirectOfferingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RegisteredDirectOfferingsMember_979a1170-5835-45ba-b60e-d80028966062" xlink:to="loc_huma_November2024RegisteredDirectOfferingMember_7686e641-cb23-43e7-9e98-f050ecd63631" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingMember_a104579d-8f04-4d3a-a741-e7071da86ca8" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_RegisteredDirectOfferingsMember_979a1170-5835-45ba-b60e-d80028966062" xlink:to="loc_huma_October2025RegisteredDirectOfferingMember_a104579d-8f04-4d3a-a741-e7071da86ca8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_7a500247-7b8f-48f3-ada4-4515cd122b27" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_7a500247-7b8f-48f3-ada4-4515cd122b27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_a064fe06-db31-4a48-8e96-cf8272446574" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_7a500247-7b8f-48f3-ada4-4515cd122b27" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_a064fe06-db31-4a48-8e96-cf8272446574" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_d8fe3ca8-e5c1-4a70-9c14-14c914ccc3e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_a064fe06-db31-4a48-8e96-cf8272446574" xlink:to="loc_us-gaap_SubsequentEventMember_d8fe3ca8-e5c1-4a70-9c14-14c914ccc3e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_0d81d472-5b53-41cd-bbd1-96031eda5e8c" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationPercentage_8fbffa37-23a1-4244-adbf-d55c19727a3e" xlink:href="huma-20250930.xsd#huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationPercentage_8fbffa37-23a1-4244-adbf-d55c19727a3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationIncreasedElectionPercentage_36f06c7f-8dd0-4d03-bf63-510b92f075e5" xlink:href="huma-20250930.xsd#huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationIncreasedElectionPercentage"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_huma_ClassOfWarrantOrRightBeneficialOwnershipLimitationIncreasedElectionPercentage_36f06c7f-8dd0-4d03-bf63-510b92f075e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_b7341550-c9f2-4bcc-a99d-f33d71aede90" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_b7341550-c9f2-4bcc-a99d-f33d71aede90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_286dfbef-c861-472e-9e26-9b672531146c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_286dfbef-c861-472e-9e26-9b672531146c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_307784a7-4032-40f0-8a02-73108fa19770" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_307784a7-4032-40f0-8a02-73108fa19770" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_548fc4cb-8e39-4f3d-9f18-2ddfdd1159c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_548fc4cb-8e39-4f3d-9f18-2ddfdd1159c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAdjustmentOfWarrants_ce1192a8-fda8-4a2d-8458-7f223674662f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueAdjustmentOfWarrants"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1de2094f-62fc-4503-8bf9-8d54b5939047" xlink:to="loc_us-gaap_FairValueAdjustmentOfWarrants_ce1192a8-fda8-4a2d-8458-7f223674662f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsRegisteredDirectOfferingWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_71326b25-e66f-4c18-b04b-1277262a3fe6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_277506cd-db2c-4eb9-a29b-4779db60fea2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_71326b25-e66f-4c18-b04b-1277262a3fe6" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_277506cd-db2c-4eb9-a29b-4779db60fea2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_54f64353-9bfc-46b9-a374-aaed06e9e201" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_277506cd-db2c-4eb9-a29b-4779db60fea2" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_54f64353-9bfc-46b9-a374-aaed06e9e201" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_54f64353-9bfc-46b9-a374-aaed06e9e201" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants180DayOctober2024Member_aa798985-fa9d-4cc6-a3ac-a92fc41232c8" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants180DayOctober2024Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:to="loc_huma_RegisteredDirectWarrants180DayOctober2024Member_aa798985-fa9d-4cc6-a3ac-a92fc41232c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants1640DayOctober2024Member_eae89d93-3b1f-42b4-8bed-029da0c23e4a" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants1640DayOctober2024Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:to="loc_huma_RegisteredDirectWarrants1640DayOctober2024Member_eae89d93-3b1f-42b4-8bed-029da0c23e4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants180DayNovember2024Member_33fd127a-938d-40fc-8ed6-aa5f0e3285d7" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants180DayNovember2024Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:to="loc_huma_RegisteredDirectWarrants180DayNovember2024Member_33fd127a-938d-40fc-8ed6-aa5f0e3285d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants1640DayNovember2024Member_47cb3721-515b-4b0f-92e0-f1cd7a069c3a" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants1640DayNovember2024Member"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_b693bfaa-01a7-4d4c-a243-ce07cf22c924" xlink:to="loc_huma_RegisteredDirectWarrants1640DayNovember2024Member_47cb3721-515b-4b0f-92e0-f1cd7a069c3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_d6d525eb-d9ec-47ed-a882-84e365db7382" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_277506cd-db2c-4eb9-a29b-4779db60fea2" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_d6d525eb-d9ec-47ed-a882-84e365db7382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_d6d525eb-d9ec-47ed-a882-84e365db7382" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputSharePriceMember_79fdd169-6dc9-40e3-8ea1-058f45adf776" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputSharePriceMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputSharePriceMember_79fdd169-6dc9-40e3-8ea1-058f45adf776" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExercisePriceMember_b9d46832-db4a-4a31-838f-78515e9724c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExercisePriceMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputExercisePriceMember_b9d46832-db4a-4a31-838f-78515e9724c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_3af8ac7c-b613-438b-a2c3-140679ab1551" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_3af8ac7c-b613-438b-a2c3-140679ab1551" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_e1e866e5-d17b-4bba-9b34-6070ad437c1c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputPriceVolatilityMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_e1e866e5-d17b-4bba-9b34-6070ad437c1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_f5dca4cf-fa10-40ac-9a58-e4e9f871bba1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_f5dca4cf-fa10-40ac-9a58-e4e9f871bba1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedDividendRateMember_8875d854-2895-4138-8cba-81c74d58bbcd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedDividendRateMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_59ef98ca-c065-436d-921e-99b92d2c1a42" xlink:to="loc_us-gaap_MeasurementInputExpectedDividendRateMember_8875d854-2895-4138-8cba-81c74d58bbcd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_1165541d-1e5d-4e8a-b330-5d9ca9d1b5e4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_277506cd-db2c-4eb9-a29b-4779db60fea2" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_1165541d-1e5d-4e8a-b330-5d9ca9d1b5e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_a5454cbd-da49-4fe9-a0ab-d2efbd550892" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingMeasurementInput"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_1165541d-1e5d-4e8a-b330-5d9ca9d1b5e4" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_a5454cbd-da49-4fe9-a0ab-d2efbd550892" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_3829c0e2-9e2f-4065-a53a-e88d43f29a96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_3829c0e2-9e2f-4065-a53a-e88d43f29a96" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_74d657d4-73ec-47fd-b2bc-0fe3cccee73e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContingentConsiderationByTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_74d657d4-73ec-47fd-b2bc-0fe3cccee73e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_640791e5-58ce-4ac0-b1a8-5af59df58bd6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContingentConsiderationTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_74d657d4-73ec-47fd-b2bc-0fe3cccee73e" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_640791e5-58ce-4ac0-b1a8-5af59df58bd6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EarnoutSharesMember_61aada85-ef43-41d1-a864-df2311439dbb" xlink:href="huma-20250930.xsd#huma_EarnoutSharesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_640791e5-58ce-4ac0-b1a8-5af59df58bd6" xlink:to="loc_huma_EarnoutSharesMember_61aada85-ef43-41d1-a864-df2311439dbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentConsiderationTranchesAxis_643af440-2976-45ef-839d-4da309536342" xlink:href="huma-20250930.xsd#huma_ContingentConsiderationTranchesAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:to="loc_huma_ContingentConsiderationTranchesAxis_643af440-2976-45ef-839d-4da309536342" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentConsiderationTranchesDomain_4a15fc01-0819-48b2-b6e5-e955d146c363" xlink:href="huma-20250930.xsd#huma_ContingentConsiderationTranchesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_ContingentConsiderationTranchesAxis_643af440-2976-45ef-839d-4da309536342" xlink:to="loc_huma_ContingentConsiderationTranchesDomain_4a15fc01-0819-48b2-b6e5-e955d146c363" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentConsiderationTrancheOneMember_8052f4b7-e606-411b-8bea-8c6ce48668e7" xlink:href="huma-20250930.xsd#huma_ContingentConsiderationTrancheOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_ContingentConsiderationTranchesDomain_4a15fc01-0819-48b2-b6e5-e955d146c363" xlink:to="loc_huma_ContingentConsiderationTrancheOneMember_8052f4b7-e606-411b-8bea-8c6ce48668e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ContingentConsiderationTrancheTwoMember_1034dfe9-5987-4831-b39b-4c83e05e5c3f" xlink:href="huma-20250930.xsd#huma_ContingentConsiderationTrancheTwoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_ContingentConsiderationTranchesDomain_4a15fc01-0819-48b2-b6e5-e955d146c363" xlink:to="loc_huma_ContingentConsiderationTrancheTwoMember_1034dfe9-5987-4831-b39b-4c83e05e5c3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_13b1dac6-54cc-4259-a63e-c18c318fbf95" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_13b1dac6-54cc-4259-a63e-c18c318fbf95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_e3123d11-7e8d-4c50-a42b-925bcdaa02a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_13b1dac6-54cc-4259-a63e-c18c318fbf95" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_e3123d11-7e8d-4c50-a42b-925bcdaa02a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_1c92ffd4-6822-440b-b108-9e0d9c85e3d1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_e3123d11-7e8d-4c50-a42b-925bcdaa02a9" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_1c92ffd4-6822-440b-b108-9e0d9c85e3d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionContingentConsiderationLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_d7b29765-87a5-410b-8d96-5fe77f13146e" xlink:to="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityShares_5ca98b69-da19-49dd-b113-a2991bbc50fc" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityShares"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityShares_5ca98b69-da19-49dd-b113-a2991bbc50fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityNumberOfTranches_a8b439ca-0fdf-4ee3-a390-5952298e3ee6" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityNumberOfTranches"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityNumberOfTranches_a8b439ca-0fdf-4ee3-a390-5952298e3ee6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilitySharesPerTranche_0de72e4b-1637-4242-9195-5602153e88ea" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilitySharesPerTranche"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilitySharesPerTranche_0de72e4b-1637-4242-9195-5602153e88ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityPerShare_e8ac554f-7284-4b67-b7f2-529fba446f1e" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityPerShare"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityPerShare_e8ac554f-7284-4b67-b7f2-529fba446f1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfTradingDays_0d1a0b7d-6769-47dc-8875-3dd54b497ce3" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfTradingDays"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfTradingDays_0d1a0b7d-6769-47dc-8875-3dd54b497ce3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfConsecutiveTradingDayPeriod_8bc9f4e8-7420-4f34-a123-640b60601403" xlink:href="huma-20250930.xsd#huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfConsecutiveTradingDayPeriod"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_huma_ReverseRecapitalizationContingentConsiderationLiabilityStockPriceTriggerNumberOfConsecutiveTradingDayPeriod_8bc9f4e8-7420-4f34-a123-640b60601403" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_cff193f9-951f-40dc-a9e0-8552bf56c9c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_cff193f9-951f-40dc-a9e0-8552bf56c9c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_789885c1-9f67-4a6b-865a-89dd1376a23e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_789885c1-9f67-4a6b-865a-89dd1376a23e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_f273ccba-440c-47f5-a35b-bf23a2052b4a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_3b5aded5-0c53-435a-906b-eaeb7289f40d" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_f273ccba-440c-47f5-a35b-bf23a2052b4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockholdersEquityDeficitandWarrantsContingentEarnoutLiabilityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_ce889794-ec16-427f-90b8-e81479c90f72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityNoteAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_3fbd896b-3a8d-4595-814b-aaea70614e40" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_ce889794-ec16-427f-90b8-e81479c90f72" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_3fbd896b-3a8d-4595-814b-aaea70614e40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_c6206e8b-30d0-4e27-9d47-206ef317f825" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_3fbd896b-3a8d-4595-814b-aaea70614e40" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_c6206e8b-30d0-4e27-9d47-206ef317f825" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_c6206e8b-30d0-4e27-9d47-206ef317f825" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputSharePriceMember_f4b6048a-bc00-4424-b2f0-9fc4207c179e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputSharePriceMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:to="loc_us-gaap_MeasurementInputSharePriceMember_f4b6048a-bc00-4424-b2f0-9fc4207c179e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_fa15a9f7-f14e-4442-b077-3421865f71c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputPriceVolatilityMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_fa15a9f7-f14e-4442-b077-3421865f71c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_0f1372a9-5fa4-461a-81b6-dcac733d42cd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_0f1372a9-5fa4-461a-81b6-dcac733d42cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedDividendRateMember_bd2be7c2-3522-4151-bb52-49c16e9c7e4c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedDividendRateMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:to="loc_us-gaap_MeasurementInputExpectedDividendRateMember_bd2be7c2-3522-4151-bb52-49c16e9c7e4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_86cacb70-06ce-4e09-a8e2-2d04205e9bba" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_cc109347-4a2f-4704-a557-fe6a515c9712" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_86cacb70-06ce-4e09-a8e2-2d04205e9bba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_2e4abb09-c0da-44c7-872c-1214018e60c7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionContingentConsiderationLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_3fbd896b-3a8d-4595-814b-aaea70614e40" xlink:to="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_2e4abb09-c0da-44c7-872c-1214018e60c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_8a88e610-c190-4d1a-a940-237cda4448f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_2e4abb09-c0da-44c7-872c-1214018e60c7" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_8a88e610-c190-4d1a-a940-237cda4448f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensationNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c93dbabc-0c0f-459c-a701-526422f0001f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c93dbabc-0c0f-459c-a701-526422f0001f" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_428e4a7a-bb6e-43b8-85a7-8ec6fc8d5d0b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:to="loc_us-gaap_AwardTypeAxis_428e4a7a-bb6e-43b8-85a7-8ec6fc8d5d0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1f7535c4-2d29-4b2b-a6ad-f1ee9880d95f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_428e4a7a-bb6e-43b8-85a7-8ec6fc8d5d0b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1f7535c4-2d29-4b2b-a6ad-f1ee9880d95f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_5125dc2c-5152-49f0-9179-703f9525c468" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1f7535c4-2d29-4b2b-a6ad-f1ee9880d95f" xlink:to="loc_us-gaap_EmployeeStockMember_5125dc2c-5152-49f0-9179-703f9525c468" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_2898e0f1-5426-473d-9cab-f055b5110004" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1f7535c4-2d29-4b2b-a6ad-f1ee9880d95f" xlink:to="loc_us-gaap_EmployeeStockOptionMember_2898e0f1-5426-473d-9cab-f055b5110004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_43d97827-99aa-42bc-8bb8-7e252e4f001c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:to="loc_us-gaap_PlanNameAxis_43d97827-99aa-42bc-8bb8-7e252e4f001c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_5a9a34a3-262d-41be-9b67-925d42b06901" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_43d97827-99aa-42bc-8bb8-7e252e4f001c" xlink:to="loc_us-gaap_PlanNameDomain_5a9a34a3-262d-41be-9b67-925d42b06901" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_LongTermIncentivePlan2021Member_4bb73a09-418e-4182-9845-75976cd13171" xlink:href="huma-20250930.xsd#huma_LongTermIncentivePlan2021Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_5a9a34a3-262d-41be-9b67-925d42b06901" xlink:to="loc_huma_LongTermIncentivePlan2021Member_4bb73a09-418e-4182-9845-75976cd13171" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OmnibusIncentivePlan2015Member_190ebed0-6530-487e-bd5a-3a7a7d74f2db" xlink:href="huma-20250930.xsd#huma_OmnibusIncentivePlan2015Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_5a9a34a3-262d-41be-9b67-925d42b06901" xlink:to="loc_huma_OmnibusIncentivePlan2015Member_190ebed0-6530-487e-bd5a-3a7a7d74f2db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_StockOptionPlan2005Member_cc72b6ad-c888-42e5-bbf1-bcde3f9066b2" xlink:href="huma-20250930.xsd#huma_StockOptionPlan2005Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_5a9a34a3-262d-41be-9b67-925d42b06901" xlink:to="loc_huma_StockOptionPlan2005Member_cc72b6ad-c888-42e5-bbf1-bcde3f9066b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_1b1c589b-d744-457a-b1e3-960be1b0232c" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:to="loc_srt_RangeAxis_1b1c589b-d744-457a-b1e3-960be1b0232c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_24ea0538-7408-4fd9-b8e2-2afbcab6e807" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_1b1c589b-d744-457a-b1e3-960be1b0232c" xlink:to="loc_srt_RangeMember_24ea0538-7408-4fd9-b8e2-2afbcab6e807" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_6ce268cc-5e22-40f2-809d-78d160be71e8" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_24ea0538-7408-4fd9-b8e2-2afbcab6e807" xlink:to="loc_srt_MinimumMember_6ce268cc-5e22-40f2-809d-78d160be71e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_b7c74485-2538-4ad9-a401-9b1a65ab85ad" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_24ea0538-7408-4fd9-b8e2-2afbcab6e807" xlink:to="loc_srt_MaximumMember_b7c74485-2538-4ad9-a401-9b1a65ab85ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d6c0afa0-3f25-4a7e-95d7-37c7dc5e518d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_af8d5ae2-b555-4dcb-b170-25a29ffac627" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_af8d5ae2-b555-4dcb-b170-25a29ffac627" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantAnnualIncreasePercent_fb76fedd-84c5-4000-b971-a7aa338e1781" xlink:href="huma-20250930.xsd#huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantAnnualIncreasePercent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantAnnualIncreasePercent_fb76fedd-84c5-4000-b971-a7aa338e1781" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_3dc9df6f-932a-4593-a625-3ca7e8ecaa7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_3dc9df6f-932a-4593-a625-3ca7e8ecaa7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_c6ff7460-2238-4d74-a933-37d66133efee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_c6ff7460-2238-4d74-a933-37d66133efee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f116f8b7-f304-43d6-8d7b-4e937efd37e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f116f8b7-f304-43d6-8d7b-4e937efd37e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans_86921ddd-863e-4538-b95b-acb815688ca6" xlink:href="huma-20250930.xsd#huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans_86921ddd-863e-4538-b95b-acb815688ca6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_8809693e-1785-4a73-a3fd-05538682ce50" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_8809693e-1785-4a73-a3fd-05538682ce50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_e766dc8b-245b-4d4a-9df3-980598b7370a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_e766dc8b-245b-4d4a-9df3-980598b7370a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_13754b5a-31c0-414e-9ab7-1651953bba1d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_13754b5a-31c0-414e-9ab7-1651953bba1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingCommencementPeriod_e50bbd98-57ff-4c58-bee7-261365e642d0" xlink:href="huma-20250930.xsd#huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingCommencementPeriod"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingCommencementPeriod_e50bbd98-57ff-4c58-bee7-261365e642d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingEndingPeriod_aaf4c722-5eb7-42f5-95f6-def9cb4d27e5" xlink:href="huma-20250930.xsd#huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingEndingPeriod"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_huma_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedVestingEndingPeriod_aaf4c722-5eb7-42f5-95f6-def9cb4d27e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_69a401fb-4663-4346-a474-57bf03d203f0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_69a401fb-4663-4346-a474-57bf03d203f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_EmployeeServiceShareBasedCompensationAccumulatedCompensationCostsCapitalized_6fdb61a7-7a2d-4d85-94dc-d5339c063e6c" xlink:href="huma-20250930.xsd#huma_EmployeeServiceShareBasedCompensationAccumulatedCompensationCostsCapitalized"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_huma_EmployeeServiceShareBasedCompensationAccumulatedCompensationCostsCapitalized_6fdb61a7-7a2d-4d85-94dc-d5339c063e6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_8df749e6-7f04-4f21-99bc-31f0b0af051a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_8df749e6-7f04-4f21-99bc-31f0b0af051a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_c09a5c6f-5b33-462c-bbc2-9701f5fcd027" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_b48097c2-b475-4aa0-ba21-5d51b2e414c5" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_c09a5c6f-5b33-462c-bbc2-9701f5fcd027" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensationAssumptionsUsedtoEstimateFairValueofStockOptionsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensationAssumptionsUsedtoEstimateFairValueofStockOptionsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensationAssumptionsUsedtoEstimateFairValueofStockOptionsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_495a72e5-1b4e-4dfc-b2ca-5f277a61e980" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4941a37d-bcff-40e3-9d93-ad8c40bde2b6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_495a72e5-1b4e-4dfc-b2ca-5f277a61e980" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4941a37d-bcff-40e3-9d93-ad8c40bde2b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_abddedce-563f-41df-a288-6f2656b9d8c0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4941a37d-bcff-40e3-9d93-ad8c40bde2b6" xlink:to="loc_us-gaap_AwardTypeAxis_abddedce-563f-41df-a288-6f2656b9d8c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_25def106-d7b9-423f-8d07-dd11d297ebe5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_abddedce-563f-41df-a288-6f2656b9d8c0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_25def106-d7b9-423f-8d07-dd11d297ebe5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_9a160a9b-76ee-47b4-a02c-add258457aae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_25def106-d7b9-423f-8d07-dd11d297ebe5" xlink:to="loc_us-gaap_EmployeeStockOptionMember_9a160a9b-76ee-47b4-a02c-add258457aae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_af1beee4-e230-40d1-8b42-4332e7c720c6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4941a37d-bcff-40e3-9d93-ad8c40bde2b6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_af1beee4-e230-40d1-8b42-4332e7c720c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_af1beee4-e230-40d1-8b42-4332e7c720c6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_47ccda88-138a-42c4-afd8-1e440ea8a777" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_47ccda88-138a-42c4-afd8-1e440ea8a777" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_3feb28a2-dd70-4f81-a81a-81d3b49d5de3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_3feb28a2-dd70-4f81-a81a-81d3b49d5de3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_04b4e489-789f-41ee-a9bd-36eb64fe33ea" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_04b4e489-789f-41ee-a9bd-36eb64fe33ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_34424312-62e4-4ef8-84c2-bf2e0326bf35" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_34424312-62e4-4ef8-84c2-bf2e0326bf35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_43cd24c3-2dee-4f16-b6ac-c4775c4056c7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_43cd24c3-2dee-4f16-b6ac-c4775c4056c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_dc3e7fa7-85a2-42e1-9509-21537d28067d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_dc3e7fa7-85a2-42e1-9509-21537d28067d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_154fe2fa-db9c-4c8f-b35f-fae5671a62f9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_154fe2fa-db9c-4c8f-b35f-fae5671a62f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_afe40835-0277-42de-8b54-073bcf7d9b9a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_bc219093-a8eb-41ad-a27c-f3fcdf5c4f7f" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_afe40835-0277-42de-8b54-073bcf7d9b9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensationStockBasedCompensationExpenseDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensationStockBasedCompensationExpenseDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensationStockBasedCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_5f10f80f-eeab-4163-adb0-1f409f99255f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_11dfbe2d-25a7-431a-8b42-b0cf551fec73" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_5f10f80f-eeab-4163-adb0-1f409f99255f" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_11dfbe2d-25a7-431a-8b42-b0cf551fec73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_4999d73d-13a5-4a6c-a580-e22a454e739a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_11dfbe2d-25a7-431a-8b42-b0cf551fec73" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_4999d73d-13a5-4a6c-a580-e22a454e739a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_7e016d0c-6944-489b-a192-2984077dbd9f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4999d73d-13a5-4a6c-a580-e22a454e739a" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_7e016d0c-6944-489b-a192-2984077dbd9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_68a93055-0ef8-42f1-b453-eaf53c02c623" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_7e016d0c-6944-489b-a192-2984077dbd9f" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_68a93055-0ef8-42f1-b453-eaf53c02c623" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_226512c1-dcd9-449b-aa53-62a4cbc9ebf9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_7e016d0c-6944-489b-a192-2984077dbd9f" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_226512c1-dcd9-449b-aa53-62a4cbc9ebf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_0a9038ca-6898-4c76-8a51-b6c84884d9cf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_11dfbe2d-25a7-431a-8b42-b0cf551fec73" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_0a9038ca-6898-4c76-8a51-b6c84884d9cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_c178b554-5ca2-49fe-bcc0-d0c8e605f29a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_0a9038ca-6898-4c76-8a51-b6c84884d9cf" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_c178b554-5ca2-49fe-bcc0-d0c8e605f29a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/StockbasedCompensationStockOptionActivityDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#StockbasedCompensationStockOptionActivityDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/StockbasedCompensationStockOptionActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_9b7ce150-7d4f-4cbe-8892-291da8ccbf08" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_9b7ce150-7d4f-4cbe-8892-291da8ccbf08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_23666656-806c-41e5-8577-de5c0d1e91a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_23666656-806c-41e5-8577-de5c0d1e91a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_05d103b3-f743-4a14-8fcf-2e2920864293" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_05d103b3-f743-4a14-8fcf-2e2920864293" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_45ec884b-6840-4195-a079-ea0518c2807a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_45ec884b-6840-4195-a079-ea0518c2807a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_70652cd0-7704-4a61-b4ae-068f2f6315ee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3751402b-7a2e-425d-ad99-641ccf9ec258" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_70652cd0-7704-4a61-b4ae-068f2f6315ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_ffe95de0-bbf1-4def-af19-27da7277ad96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_ffe95de0-bbf1-4def-af19-27da7277ad96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_16fb1f8c-f94e-4c7c-91f9-1854a2af498a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_16fb1f8c-f94e-4c7c-91f9-1854a2af498a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_99636f01-a195-4fd7-bbf4-3eedf98643c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_99636f01-a195-4fd7-bbf4-3eedf98643c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_1e238abd-0ee1-4bb9-9507-3dd03c5e860a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_1e238abd-0ee1-4bb9-9507-3dd03c5e860a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_02fab693-b8e2-4e21-be37-e383c8fc5af1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_02fab693-b8e2-4e21-be37-e383c8fc5af1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_16ffe911-a8c3-4edb-a642-33f49b51cf00" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_16ffe911-a8c3-4edb-a642-33f49b51cf00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_6bc1ee41-bf0d-4fab-93c5-74033843f4c7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_e5d2d04e-d85a-40ef-9ad8-5a8439d5c869" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_6bc1ee41-bf0d-4fab-93c5-74033843f4c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_c079ed48-de40-4df8-8a0d-6a5c2346e7c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_c079ed48-de40-4df8-8a0d-6a5c2346e7c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_c7bcd7c6-318c-4d49-8b02-f1d4701f610c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_c7bcd7c6-318c-4d49-8b02-f1d4701f610c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e4ee3585-9efc-43db-85a3-18d10bb170dd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_6c9d3736-d7e4-45f4-b56c-0a39c7efbcd0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_6c9d3736-d7e4-45f4-b56c-0a39c7efbcd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_56752297-5e52-4b01-b35c-ec3940095ae8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_56752297-5e52-4b01-b35c-ec3940095ae8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_d5dbbdb5-c5e9-4218-82ad-c33c6367925b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_d5dbbdb5-c5e9-4218-82ad-c33c6367925b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_ee11aebe-52ee-4a64-9a22-56c3cfe47d66" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_ee11aebe-52ee-4a64-9a22-56c3cfe47d66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_9629751d-7e0b-414a-ba22-62808d33cdc0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_9629751d-7e0b-414a-ba22-62808d33cdc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_6eeeaf32-c417-4b63-a6fe-cc4088db64ea" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_4b68cb31-37de-42e4-ad0d-166d633b3551" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_6eeeaf32-c417-4b63-a6fe-cc4088db64ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/IncomeTaxesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#IncomeTaxesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/IncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_c40aa8c5-a655-484d-8246-756e9f0504e9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_495e36a4-dc55-4f37-92f1-a70e1968848e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c40aa8c5-a655-484d-8246-756e9f0504e9" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_495e36a4-dc55-4f37-92f1-a70e1968848e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_0915001e-efd4-4c69-9a5b-32a8b074fdb1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c40aa8c5-a655-484d-8246-756e9f0504e9" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_0915001e-efd4-4c69-9a5b-32a8b074fdb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/CommitmentsandContingenciesDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#CommitmentsandContingenciesDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/CommitmentsandContingenciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_a5c70842-7f72-4d48-9a88-4e8f9af39c37" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_a5c70842-7f72-4d48-9a88-4e8f9af39c37" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_51683da1-450e-42ff-b989-73a0df149dce" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_srt_CounterpartyNameAxis_51683da1-450e-42ff-b989-73a0df149dce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_98d567a5-f5d4-47a5-8694-8b769ab8a279" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_51683da1-450e-42ff-b989-73a0df149dce" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_98d567a5-f5d4-47a5-8694-8b769ab8a279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DukeUniversityMember_13f4e1af-0325-4875-8d58-dae4c65278a8" xlink:href="huma-20250930.xsd#huma_DukeUniversityMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_98d567a5-f5d4-47a5-8694-8b769ab8a279" xlink:to="loc_huma_DukeUniversityMember_13f4e1af-0325-4875-8d58-dae4c65278a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_YaleUniversityMember_623d978e-889d-4a73-80eb-77ef5aaef09b" xlink:href="huma-20250930.xsd#huma_YaleUniversityMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_98d567a5-f5d4-47a5-8694-8b769ab8a279" xlink:to="loc_huma_YaleUniversityMember_623d978e-889d-4a73-80eb-77ef5aaef09b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_f5e713d0-ec25-46d6-892e-323230e546ea" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_srt_ProductOrServiceAxis_f5e713d0-ec25-46d6-892e-323230e546ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_7da3e5b7-5444-4cb2-8015-d1306b8066de" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_f5e713d0-ec25-46d6-892e-323230e546ea" xlink:to="loc_srt_ProductsAndServicesDomain_7da3e5b7-5444-4cb2-8015-d1306b8066de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DecellularizedTissueEngineeringPatentRightsMember_4a571596-bab4-40ac-ab6a-9df1935d755b" xlink:href="huma-20250930.xsd#huma_DecellularizedTissueEngineeringPatentRightsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_7da3e5b7-5444-4cb2-8015-d1306b8066de" xlink:to="loc_huma_DecellularizedTissueEngineeringPatentRightsMember_4a571596-bab4-40ac-ab6a-9df1935d755b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_BVPPatentRightsMember_4f1283dc-28a2-41da-892e-89b0aec38df3" xlink:href="huma-20250930.xsd#huma_BVPPatentRightsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_7da3e5b7-5444-4cb2-8015-d1306b8066de" xlink:to="loc_huma_BVPPatentRightsMember_4f1283dc-28a2-41da-892e-89b0aec38df3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TubularProsthesesPatentRightsMember_afacaac7-f52e-4c82-93f0-064a10d5ed5a" xlink:href="huma-20250930.xsd#huma_TubularProsthesesPatentRightsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_7da3e5b7-5444-4cb2-8015-d1306b8066de" xlink:to="loc_huma_TubularProsthesesPatentRightsMember_afacaac7-f52e-4c82-93f0-064a10d5ed5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_5cd924f0-147f-4f10-9de3-bb6c9118875f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_us-gaap_TypeOfArrangementAxis_5cd924f0-147f-4f10-9de3-bb6c9118875f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_2c7e448c-e792-4eb3-a6e3-b08850f047cd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_5cd924f0-147f-4f10-9de3-bb6c9118875f" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_2c7e448c-e792-4eb3-a6e3-b08850f047cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_LicenseAgreementMember_3c0d26e4-282b-4f65-b5a6-de7b8b572a0c" xlink:href="huma-20250930.xsd#huma_LicenseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_2c7e448c-e792-4eb3-a6e3-b08850f047cd" xlink:to="loc_huma_LicenseAgreementMember_3c0d26e4-282b-4f65-b5a6-de7b8b572a0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementMilestonePaymentsAxis_e562951f-1149-4981-9260-97a44c492994" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementMilestonePaymentsAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_huma_CollaborativeArrangementMilestonePaymentsAxis_e562951f-1149-4981-9260-97a44c492994" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementMilestonePaymentsDomain_e294373f-87d9-48dd-a9ea-536c0615b8cf" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementMilestonePaymentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CollaborativeArrangementMilestonePaymentsAxis_e562951f-1149-4981-9260-97a44c492994" xlink:to="loc_huma_CollaborativeArrangementMilestonePaymentsDomain_e294373f-87d9-48dd-a9ea-536c0615b8cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegulatoryMilestoneMember_4a02b730-b4ea-4d70-a1fd-97d065753000" xlink:href="huma-20250930.xsd#huma_RegulatoryMilestoneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CollaborativeArrangementMilestonePaymentsDomain_e294373f-87d9-48dd-a9ea-536c0615b8cf" xlink:to="loc_huma_RegulatoryMilestoneMember_4a02b730-b4ea-4d70-a1fd-97d065753000" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CommercialMilestoneMember_d9d3e859-39d7-4d5c-8682-d30d906c9b75" xlink:href="huma-20250930.xsd#huma_CommercialMilestoneMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_CollaborativeArrangementMilestonePaymentsDomain_e294373f-87d9-48dd-a9ea-536c0615b8cf" xlink:to="loc_huma_CommercialMilestoneMember_d9d3e859-39d7-4d5c-8682-d30d906c9b75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_daf3f4af-4699-4a3f-b827-fb91cbc9f76c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_us-gaap_FinancialInstrumentAxis_daf3f4af-4699-4a3f-b827-fb91cbc9f76c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_78749a67-65fc-4230-81be-6034b03d3728" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_daf3f4af-4699-4a3f-b827-fb91cbc9f76c" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_78749a67-65fc-4230-81be-6034b03d3728" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_JDRFAgreementMember_5170351c-2671-49a7-89a3-7e1a4917a701" xlink:href="huma-20250930.xsd#huma_JDRFAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_78749a67-65fc-4230-81be-6034b03d3728" xlink:to="loc_huma_JDRFAgreementMember_5170351c-2671-49a7-89a3-7e1a4917a701" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PaymentInstallmentAxis_177f324f-abc0-4475-8153-41fd5680bf6a" xlink:href="huma-20250930.xsd#huma_PaymentInstallmentAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_huma_PaymentInstallmentAxis_177f324f-abc0-4475-8153-41fd5680bf6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_PaymentInstallmentDomain_edbb51a1-33fe-4671-ac48-5d109a5fd14c" xlink:href="huma-20250930.xsd#huma_PaymentInstallmentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_PaymentInstallmentAxis_177f324f-abc0-4475-8153-41fd5680bf6a" xlink:to="loc_huma_PaymentInstallmentDomain_edbb51a1-33fe-4671-ac48-5d109a5fd14c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FirstMilestonePaymentMember_100a3b88-31ad-4b14-a62e-ef7e6c33faa2" xlink:href="huma-20250930.xsd#huma_FirstMilestonePaymentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_PaymentInstallmentDomain_edbb51a1-33fe-4671-ac48-5d109a5fd14c" xlink:to="loc_huma_FirstMilestonePaymentMember_100a3b88-31ad-4b14-a62e-ef7e6c33faa2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_SecondMilestonePaymentMember_c688a400-ee1f-4383-b404-1e2acfb12529" xlink:href="huma-20250930.xsd#huma_SecondMilestonePaymentMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_PaymentInstallmentDomain_edbb51a1-33fe-4671-ac48-5d109a5fd14c" xlink:to="loc_huma_SecondMilestonePaymentMember_c688a400-ee1f-4383-b404-1e2acfb12529" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ThirdMilestonePaymentMember_90716b0e-e1b4-4c08-a087-27de2ca2e0f0" xlink:href="huma-20250930.xsd#huma_ThirdMilestonePaymentMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_huma_PaymentInstallmentDomain_edbb51a1-33fe-4671-ac48-5d109a5fd14c" xlink:to="loc_huma_ThirdMilestonePaymentMember_90716b0e-e1b4-4c08-a087-27de2ca2e0f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_dbd4e81a-7337-4ea2-b3fd-8fde18592713" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_dbd4e81a-7337-4ea2-b3fd-8fde18592713" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_ddf409e0-bb18-41a9-8aea-9ef250c19201" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_dbd4e81a-7337-4ea2-b3fd-8fde18592713" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_ddf409e0-bb18-41a9-8aea-9ef250c19201" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_0ce04745-e3b1-4412-8c26-bb82e54b2613" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ddf409e0-bb18-41a9-8aea-9ef250c19201" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_0ce04745-e3b1-4412-8c26-bb82e54b2613" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_3c61092b-d9fe-4d1f-9145-3ecae16031a5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ddf409e0-bb18-41a9-8aea-9ef250c19201" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_3c61092b-d9fe-4d1f-9145-3ecae16031a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_f62d6a43-6c3f-4c25-bcd9-02a655b407b0" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_LitigationCaseAxis"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_srt_LitigationCaseAxis_f62d6a43-6c3f-4c25-bcd9-02a655b407b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_dbf47513-714f-4832-ae62-7baad4f95209" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_LitigationCaseTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_f62d6a43-6c3f-4c25-bcd9-02a655b407b0" xlink:to="loc_srt_LitigationCaseTypeDomain_dbf47513-714f-4832-ae62-7baad4f95209" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ConsolidatedDerivativeActionMember_fba7f243-46a4-4976-bba5-a87572b63126" xlink:href="huma-20250930.xsd#huma_ConsolidatedDerivativeActionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_dbf47513-714f-4832-ae62-7baad4f95209" xlink:to="loc_huma_ConsolidatedDerivativeActionMember_fba7f243-46a4-4976-bba5-a87572b63126" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationStatusAxis_e7da4a49-864c-45a3-b2c2-b01cd6d33f98" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LitigationStatusAxis"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_us-gaap_LitigationStatusAxis_e7da4a49-864c-45a3-b2c2-b01cd6d33f98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationStatusDomain_56a8443c-be00-40f6-8eab-d56f6149e103" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LitigationStatusDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusAxis_e7da4a49-864c-45a3-b2c2-b01cd6d33f98" xlink:to="loc_us-gaap_LitigationStatusDomain_56a8443c-be00-40f6-8eab-d56f6149e103" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PendingLitigationMember_d8c227c4-9609-4eb3-80be-31d5ad43366e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PendingLitigationMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusDomain_56a8443c-be00-40f6-8eab-d56f6149e103" xlink:to="loc_us-gaap_PendingLitigationMember_d8c227c4-9609-4eb3-80be-31d5ad43366e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_fae5693a-330b-4a8f-a464-fad150a8a147" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementSharesIssued_a688b13e-327b-47ab-a8cd-c22bd56fe9fe" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementSharesIssued"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementSharesIssued_a688b13e-327b-47ab-a8cd-c22bd56fe9fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementExpirationPeriod_a4e90e5e-e513-4e19-b17f-671c1167dfed" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementExpirationPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementExpirationPeriod_a4e90e5e-e513-4e19-b17f-671c1167dfed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_TerminationPeriod_8312b61f-b0ff-44b6-9cc0-bf823097ade4" xlink:href="huma-20250930.xsd#huma_TerminationPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_TerminationPeriod_8312b61f-b0ff-44b6-9cc0-bf823097ade4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementLicenseFeePaid_05fb5488-6bfc-46c5-af85-224d39cf0247" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementLicenseFeePaid"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementLicenseFeePaid_05fb5488-6bfc-46c5-af85-224d39cf0247" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementLicenseFeePayable_76207d58-0373-4d30-98cc-1a31b474757b" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementLicenseFeePayable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementLicenseFeePayable_76207d58-0373-4d30-98cc-1a31b474757b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementMaximumAnnualMaintenanceFee_894780e9-c7bd-4e50-9076-21e03c0aa7ae" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementMaximumAnnualMaintenanceFee"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementMaximumAnnualMaintenanceFee_894780e9-c7bd-4e50-9076-21e03c0aa7ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CollaborativeArrangementMilestonePayments_7f89e3a6-09f4-4ad5-8e51-9ea78a2c02e3" xlink:href="huma-20250930.xsd#huma_CollaborativeArrangementMilestonePayments"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CollaborativeArrangementMilestonePayments_7f89e3a6-09f4-4ad5-8e51-9ea78a2c02e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MilestonePaymentPotentiallyReceivable_9129745d-13a0-43ca-aa83-929a21f7f011" xlink:href="huma-20250930.xsd#huma_MilestonePaymentPotentiallyReceivable"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_MilestonePaymentPotentiallyReceivable_9129745d-13a0-43ca-aa83-929a21f7f011" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_MilestonePaymentsReceived_efa086ef-7bea-413c-8bb6-365e805be16b" xlink:href="huma-20250930.xsd#huma_MilestonePaymentsReceived"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_MilestonePaymentsReceived_efa086ef-7bea-413c-8bb6-365e805be16b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_OneTimeRoyaltyAmountActualAwardMultiplier_51032333-298e-424c-a8d8-945889dada12" xlink:href="huma-20250930.xsd#huma_OneTimeRoyaltyAmountActualAwardMultiplier"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_OneTimeRoyaltyAmountActualAwardMultiplier_51032333-298e-424c-a8d8-945889dada12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_NumberOfInstallments_65f8909a-ee9e-485b-89dc-c8173b9ff5b1" xlink:href="huma-20250930.xsd#huma_NumberOfInstallments"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_NumberOfInstallments_65f8909a-ee9e-485b-89dc-c8173b9ff5b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_NetSalesMinimumThresholdForAdditionalRoyalty_aa171e22-bc07-496e-8e8b-9fc944e55e86" xlink:href="huma-20250930.xsd#huma_NetSalesMinimumThresholdForAdditionalRoyalty"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_NetSalesMinimumThresholdForAdditionalRoyalty_aa171e22-bc07-496e-8e8b-9fc944e55e86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DispositionPaymentPercentage_080f7ff3-93ad-40b3-bbd6-158545623876" xlink:href="huma-20250930.xsd#huma_DispositionPaymentPercentage"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_DispositionPaymentPercentage_080f7ff3-93ad-40b3-bbd6-158545623876" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_CurePeriod_2b82626e-06f6-4827-bd72-f580575619f0" xlink:href="huma-20250930.xsd#huma_CurePeriod"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_CurePeriod_2b82626e-06f6-4827-bd72-f580575619f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_3c39c026-38b9-442a-9bbf-32d8ff2e75f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_3c39c026-38b9-442a-9bbf-32d8ff2e75f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_8935292e-4a28-441e-9c71-9496ecf6fb1e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_8935292e-4a28-441e-9c71-9496ecf6fb1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeveranceCosts1_2df45543-9680-4552-9557-1c9e94e2731e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SeveranceCosts1"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_us-gaap_SeveranceCosts1_2df45543-9680-4552-9557-1c9e94e2731e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRestructuring_6404b12f-7f4f-485b-9b18-da1b245c7080" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRestructuring"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_us-gaap_PaymentsForRestructuring_6404b12f-7f4f-485b-9b18-da1b245c7080" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserve_e999e776-50d4-4c82-8241-204304f14b5c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringReserve"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_us-gaap_RestructuringReserve_e999e776-50d4-4c82-8241-204304f14b5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_NumberOfVerifiedStockholderDerivativeActions_4ab6cb4a-06f0-450f-8b87-cd1e5b256704" xlink:href="huma-20250930.xsd#huma_NumberOfVerifiedStockholderDerivativeActions"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_f404a02b-234f-4283-91b7-e7797b97e06b" xlink:to="loc_huma_NumberOfVerifiedStockholderDerivativeActions_4ab6cb4a-06f0-450f-8b87-cd1e5b256704" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/RelatedPartyTransactionsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#RelatedPartyTransactionsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/RelatedPartyTransactionsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_c9f38f75-6821-477c-ab78-2b7df4493ea9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_5033ac5f-53a4-4d27-92e3-58c1c28a4ea1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_c9f38f75-6821-477c-ab78-2b7df4493ea9" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_5033ac5f-53a4-4d27-92e3-58c1c28a4ea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_92b5c845-8b22-46e1-b047-7ecca78a691f" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_5033ac5f-53a4-4d27-92e3-58c1c28a4ea1" xlink:to="loc_srt_CounterpartyNameAxis_92b5c845-8b22-46e1-b047-7ecca78a691f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8195c241-29d3-48a8-877d-942cdb8fc4f1" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_92b5c845-8b22-46e1-b047-7ecca78a691f" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8195c241-29d3-48a8-877d-942cdb8fc4f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FreseniusMedicalCareMember_1f25938e-e55a-42d8-8795-d739b2c3d78e" xlink:href="huma-20250930.xsd#huma_FreseniusMedicalCareMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8195c241-29d3-48a8-877d-942cdb8fc4f1" xlink:to="loc_huma_FreseniusMedicalCareMember_1f25938e-e55a-42d8-8795-d739b2c3d78e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FreseniusMedicalCareDeutschlandGmbHMember_a9db6722-d251-4a2a-8478-461c02bc4c18" xlink:href="huma-20250930.xsd#huma_FreseniusMedicalCareDeutschlandGmbHMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8195c241-29d3-48a8-877d-942cdb8fc4f1" xlink:to="loc_huma_FreseniusMedicalCareDeutschlandGmbHMember_a9db6722-d251-4a2a-8478-461c02bc4c18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_FrenovaRenalResearchMember_0983fce3-87df-4fe4-9a80-7f1347efa5be" xlink:href="huma-20250930.xsd#huma_FrenovaRenalResearchMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8195c241-29d3-48a8-877d-942cdb8fc4f1" xlink:to="loc_huma_FrenovaRenalResearchMember_0983fce3-87df-4fe4-9a80-7f1347efa5be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_87ff9581-a972-4857-aa1d-34ccbaf9936f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_5033ac5f-53a4-4d27-92e3-58c1c28a4ea1" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_87ff9581-a972-4857-aa1d-34ccbaf9936f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_a3751608-fe45-4ce5-8fee-da9c0a85ac40" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_87ff9581-a972-4857-aa1d-34ccbaf9936f" xlink:to="loc_us-gaap_RelatedPartyDomain_a3751608-fe45-4ce5-8fee-da9c0a85ac40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyMember_b9d95e17-57a8-4d8d-8962-3a71de0f025b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_a3751608-fe45-4ce5-8fee-da9c0a85ac40" xlink:to="loc_us-gaap_RelatedPartyMember_b9d95e17-57a8-4d8d-8962-3a71de0f025b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RelatedPartyTransactionLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_5033ac5f-53a4-4d27-92e3-58c1c28a4ea1" xlink:to="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOrSaleOfEquity_e7810e12-da78-45cb-be69-91df2a265df4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOrSaleOfEquity"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_ProceedsFromIssuanceOrSaleOfEquity_e7810e12-da78-45cb-be69-91df2a265df4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConversionOfStockSharesIssued1_37136d84-60a1-4210-9f5d-f1524ed98633" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConversionOfStockSharesIssued1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_ConversionOfStockSharesIssued1_37136d84-60a1-4210-9f5d-f1524ed98633" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfPrivatePlacement_96c30b84-b8bc-4d88-a891-fd2e66981860" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfPrivatePlacement"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfPrivatePlacement_96c30b84-b8bc-4d88-a891-fd2e66981860" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_2715dbf8-3909-4e1b-b88b-acd66ac7aea1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_CommonStockSharesIssued_2715dbf8-3909-4e1b-b88b-acd66ac7aea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_DistributionAgreementTerminationPeriod_79cf1869-dfb4-4aa2-b279-344a9e72c953" xlink:href="huma-20250930.xsd#huma_DistributionAgreementTerminationPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_huma_DistributionAgreementTerminationPeriod_79cf1869-dfb4-4aa2-b279-344a9e72c953" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_b1c4e3eb-8f90-409d-bf5c-64c43d75da79" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_AccountsPayableCurrent_b1c4e3eb-8f90-409d-bf5c-64c43d75da79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_ClinicalResearchServicesExpense_e80c8a4e-4d56-47be-9984-96bc2716d6a6" xlink:href="huma-20250930.xsd#huma_ClinicalResearchServicesExpense"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_huma_ClinicalResearchServicesExpense_e80c8a4e-4d56-47be-9984-96bc2716d6a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_8a5c794b-9192-402f-a6ab-663de7bb9c35" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_bdd1da95-4d0a-45c4-87e0-0846da9ba334" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_8a5c794b-9192-402f-a6ab-663de7bb9c35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.humacyte.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="huma-20250930.xsd#SubsequentEventsDetails"/>
  <link:presentationLink xlink:role="http://www.humacyte.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_68ca29cf-90b9-4942-8c3d-6ebfebea6bcb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_68ca29cf-90b9-4942-8c3d-6ebfebea6bcb" xlink:to="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_87ecb362-c797-4925-8404-c97cc82f2645" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_87ecb362-c797-4925-8404-c97cc82f2645" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_92e39d15-804e-4543-a873-62b48e104196" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_87ecb362-c797-4925-8404-c97cc82f2645" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_92e39d15-804e-4543-a873-62b48e104196" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_6a07d383-8ae9-4a0e-adba-07480c51cb4e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_92e39d15-804e-4543-a873-62b48e104196" xlink:to="loc_us-gaap_SubsequentEventMember_6a07d383-8ae9-4a0e-adba-07480c51cb4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_91a34a4a-4c19-4a2d-aeb1-aecb1898de24" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_91a34a4a-4c19-4a2d-aeb1-aecb1898de24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d0749346-36e2-4479-8e52-53cd11fc2e7c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_91a34a4a-4c19-4a2d-aeb1-aecb1898de24" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d0749346-36e2-4479-8e52-53cd11fc2e7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingMember_cc760b03-6371-4c3f-a8b3-e1a631973726" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_d0749346-36e2-4479-8e52-53cd11fc2e7c" xlink:to="loc_huma_October2025RegisteredDirectOfferingMember_cc760b03-6371-4c3f-a8b3-e1a631973726" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_34df09d5-011a-4c4a-a251-2fba2c2bf611" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_34df09d5-011a-4c4a-a251-2fba2c2bf611" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_97845644-9129-40bd-b814-60421536d474" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_34df09d5-011a-4c4a-a251-2fba2c2bf611" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_97845644-9129-40bd-b814-60421536d474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_596ae061-6445-461d-b29e-947a0c06d51d" xlink:href="huma-20250930.xsd#huma_October2025RegisteredDirectOfferingWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_97845644-9129-40bd-b814-60421536d474" xlink:to="loc_huma_October2025RegisteredDirectOfferingWarrantsMember_596ae061-6445-461d-b29e-947a0c06d51d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_huma_RegisteredDirectWarrants180DayOctober2025Member_a8ce3262-ab41-4115-8327-c62c95fc7959" xlink:href="huma-20250930.xsd#huma_RegisteredDirectWarrants180DayOctober2025Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_97845644-9129-40bd-b814-60421536d474" xlink:to="loc_huma_RegisteredDirectWarrants180DayOctober2025Member_a8ce3262-ab41-4115-8327-c62c95fc7959" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_86cbdbc6-c41e-46c7-a8fb-68f9067fa3a9" xlink:to="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_e9a1c447-6cd1-4819-aa4a-d256160b3b78" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_e9a1c447-6cd1-4819-aa4a-d256160b3b78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_fe814ee5-4a2d-4320-9bdf-e9232a8c844f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_fe814ee5-4a2d-4320-9bdf-e9232a8c844f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_7f8c57c2-cb7d-46a8-a8ac-0753f03b7a72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_7f8c57c2-cb7d-46a8-a8ac-0753f03b7a72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_b94f5986-80b7-4f31-b4fd-f7be3cf317bd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_b94f5986-80b7-4f31-b4fd-f7be3cf317bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_f5cc22ff-c2ff-43fb-8044-512387dc43b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_f5cc22ff-c2ff-43fb-8044-512387dc43b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_bbe35544-0a90-4e81-a66e-35c8c4c8bd24" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_91621cf0-5b28-4839-b9f1-9872b37ad364" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_bbe35544-0a90-4e81-a66e-35c8c4c8bd24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/AwardTimingDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#AwardTimingDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/AwardTimingDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgDiscLineItems" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgDiscLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMnpiDiscTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgMnpiDiscTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMnpiDiscTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMethodTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgMethodTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMethodTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgPredtrmndFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgPredtrmndFlag"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgPredtrmndFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMnpiCnsdrdFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgMnpiCnsdrdFlag"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMnpiCnsdrdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgHowMnpiCnsdrdTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardTmgHowMnpiCnsdrdTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgHowMnpiCnsdrdTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MnpiDiscTimedForCompValFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_MnpiDiscTimedForCompValFlag"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_MnpiDiscTimedForCompValFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardsCloseToMnpiDiscTableTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardsCloseToMnpiDiscTable"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:to="loc_us-gaap_AwardTypeAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_us-gaap_EmployeeStockOptionMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockAppreciationRightsSARSMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscIndName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardsCloseToMnpiDiscIndName"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardUndrlygSecuritiesAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardUndrlygSecuritiesAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardUndrlygSecuritiesAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardExrcPrice" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardExrcPrice"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardExrcPrice" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardGrantDateFairValue" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AwardGrantDateFairValue"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardGrantDateFairValue" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_UndrlygSecurityMktPriceChngPct" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_UndrlygSecurityMktPriceChngPct"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_UndrlygSecurityMktPriceChngPct" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/ErrCompDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ErrCompDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/ErrCompDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_RecoveryOfErrCompDisclosureLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ErrCompRecoveryTable" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ErrCompRecoveryTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ErrCompRecoveryTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDateAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_RestatementDateAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ErrCompRecoveryTable" xlink:to="loc_ecd_RestatementDateAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ErrCompRecoveryTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonNeosMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonNeosMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllIndividualsMember" xlink:to="loc_ecd_NonNeosMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDeterminationDate" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_RestatementDeterminationDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_RestatementDeterminationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtErrCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AggtErrCompAmt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_AggtErrCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ErrCompAnalysisTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ErrCompAnalysisTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ErrCompAnalysisTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_StkPrcOrTsrEstimationMethodTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_StkPrcOrTsrEstimationMethodTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_StkPrcOrTsrEstimationMethodTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingAggtErrCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_OutstandingAggtErrCompAmt"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingAggtErrCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtErrCompNotYetDeterminedTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AggtErrCompNotYetDeterminedTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_AggtErrCompNotYetDeterminedTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryIndName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ForgoneRecoveryIndName"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingRecoveryIndName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_OutstandingRecoveryIndName"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingRecoveryIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingRecoveryCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_OutstandingRecoveryCompAmt"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingRecoveryCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDoesNotRequireRecoveryTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_RestatementDoesNotRequireRecoveryTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_RestatementDoesNotRequireRecoveryTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/PvpDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#PvpDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/PvpDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PayVsPerformanceDisclosureLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PvpTable" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PvpTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PvpTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ExecutiveCategoryAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ExecutiveCategoryAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_ExecutiveCategoryAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllExecutiveCategoriesMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllExecutiveCategoriesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ExecutiveCategoryAxis" xlink:to="loc_ecd_AllExecutiveCategoriesMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeoMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllExecutiveCategoriesMember" xlink:to="loc_ecd_PeoMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonPeoNeoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllExecutiveCategoriesMember" xlink:to="loc_ecd_NonPeoNeoMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToCompAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AdjToCompAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_AdjToCompAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllAdjToCompMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllAdjToCompMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AdjToCompAxis" xlink:to="loc_ecd_AllAdjToCompMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AggtPnsnAdjsSvcCstMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnAdjsSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PnsnAdjsSvcCstMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:to="loc_ecd_PnsnAdjsSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnAdjsPrrSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PnsnAdjsPrrSvcCstMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:to="loc_ecd_PnsnAdjsPrrSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_EqtyAwrdsAdjsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_EqtyAwrdsAdjsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsMember" xlink:to="loc_ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsMember" xlink:to="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MeasureAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_MeasureAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_MeasureAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PvpTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PvpTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PvpTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CoSelectedMeasureName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CoSelectedMeasureName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CoSelectedMeasureName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NamedExecutiveOfficersFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NamedExecutiveOfficersFnTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NamedExecutiveOfficersFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeerGroupIssuersFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeerGroupIssuersFnTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeerGroupIssuersFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChangedPeerGroupFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_ChangedPeerGroupFnTextBlock"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_ChangedPeerGroupFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoTotalCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeoTotalCompAmt"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoTotalCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoActuallyPaidCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeoActuallyPaidCompAmt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoActuallyPaidCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToPeoCompFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AdjToPeoCompFnTextBlock"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToPeoCompFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoAvgTotalCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonPeoNeoAvgTotalCompAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonPeoNeoAvgTotalCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoAvgCompActuallyPaidAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonPeoNeoAvgCompActuallyPaidAmt"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonPeoNeoAvgCompActuallyPaidAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToNonPeoNeoCompFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AdjToNonPeoNeoCompFnTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToNonPeoNeoCompFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EquityValuationAssumptionDifferenceFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_EquityValuationAssumptionDifferenceFnTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_EquityValuationAssumptionDifferenceFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsNetIncomeTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CompActuallyPaidVsNetIncomeTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsNetIncomeTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TotalShareholderRtnVsPeerGroupTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TotalShareholderRtnVsPeerGroupTextBlock"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TotalShareholderRtnVsPeerGroupTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsOtherMeasureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CompActuallyPaidVsOtherMeasureTextBlock"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsOtherMeasureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TabularListTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TabularListTableTextBlock"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TabularListTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TotalShareholderRtnAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TotalShareholderRtnAmt"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TotalShareholderRtnAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeerGroupTotalShareholderRtnAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeerGroupTotalShareholderRtnAmt"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeerGroupTotalShareholderRtnAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CoSelectedMeasureAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_CoSelectedMeasureAmt"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CoSelectedMeasureAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OtherPerfMeasureAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_OtherPerfMeasureAmt"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_OtherPerfMeasureAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AdjToCompAmt"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PeoName"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MeasureName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_MeasureName"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_MeasureName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonGaapMeasureDescriptionTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonGaapMeasureDescriptionTextBlock"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonGaapMeasureDescriptionTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Additional402vDisclosureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_Additional402vDisclosureTextBlock"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_Additional402vDisclosureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnBnftsAdjFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_PnsnBnftsAdjFnTextBlock"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PnsnBnftsAdjFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_EqtyAwrdsAdjFnTextBlock"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_EqtyAwrdsAdjFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#InsiderTradingArrangements"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTradingArrLineItems" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_InsiderTradingArrLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TradingArrByIndTable" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TradingArrByIndTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TradingArrByIndTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TradingArrAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TradingArrAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrByIndTable" xlink:to="loc_ecd_TradingArrAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllTradingArrangementsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllTradingArrangementsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrAxis" xlink:to="loc_ecd_AllTradingArrangementsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrByIndTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MtrlTermsOfTrdArrTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_MtrlTermsOfTrdArrTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_MtrlTermsOfTrdArrTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrIndName" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrIndName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrIndTitle" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrIndTitle"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrIndTitle" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Rule10b51ArrAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_Rule10b51ArrAdoptedFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_Rule10b51ArrAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonRule10b51ArrAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonRule10b51ArrAdoptedFlag"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_NonRule10b51ArrAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrAdoptionDate" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrAdoptionDate"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrAdoptionDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Rule10b51ArrTrmntdFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_Rule10b51ArrTrmntdFlag"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_Rule10b51ArrTrmntdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonRule10b51ArrTrmntdFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_NonRule10b51ArrTrmntdFlag"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_NonRule10b51ArrTrmntdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrTerminationDate" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrTerminationDate"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrTerminationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrExpirationDate" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrExpirationDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrExpirationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrDuration" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrDuration"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrDuration" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrSecuritiesAggAvailAmt" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_TrdArrSecuritiesAggAvailAmt"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrSecuritiesAggAvailAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/InsiderTradingPoliciesProc" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#InsiderTradingPoliciesProc"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/InsiderTradingPoliciesProc" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_InsiderTradingPoliciesProcLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTrdPoliciesProcAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_InsiderTrdPoliciesProcAdoptedFlag"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:to="loc_ecd_InsiderTrdPoliciesProcAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd#ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:to="loc_ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
